4-hydroxyphenazone-4095 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the 4-hydroxyphenazone-4095 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AKAP8L A kinase (PRKA) anchor protein 8-like
ANKH ANKH inorganic pyrophosphate transport regulator
APOC4 apolipoprotein C-IV
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
BCL2L10 BCL2-like 10 (apoptosis facilitator)
C1QTNF3 C1q and tumor necrosis factor related protein 3
C2CD2L C2CD2-like
CADM1 cell adhesion molecule 1
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CCDC64 coiled-coil domain containing 64
CCKBR cholecystokinin B receptor
CD7 CD7 molecule
CDC14B cell division cycle 14B
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CNTN1 contactin 1
CPN2 carboxypeptidase N, polypeptide 2
CTRC chymotrypsin C (caldecrin)
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DOK2 docking protein 2, 56kDa
DSCR4 Down syndrome critical region 4
EDNRA endothelin receptor type A
EHD2 EH-domain containing 2
EIF3F eukaryotic translation initiation factor 3, subunit F
FAS Fas cell surface death receptor
FRMD1 FERM domain containing 1
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GH1 growth hormone 1
GLP1R glucagon-like peptide 1 receptor
GPX3 glutathione peroxidase 3
GRB7 growth factor receptor-bound protein 7
GRM7 glutamate receptor, metabotropic 7
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
HABP2 hyaluronan binding protein 2
HBB hemoglobin, beta
HPSE2 heparanase 2 (inactive)
ICOSLG inducible T-cell co-stimulator ligand
IQCC IQ motif containing C
IRF4 interferon regulatory factor 4
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB8 integrin, beta 8
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCNIP2 Kv channel interacting protein 2
KLHL25 kelch-like family member 25
LEFTY2 left-right determination factor 2
LMNA lamin A/C
LOC1720 dihydrofolate reductase pseudogene
MEOX2 mesenchyme homeobox 2
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MSX2 msh homeobox 2
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYH2 myosin, heavy chain 2, skeletal muscle, adult
NCOR2 nuclear receptor corepressor 2
NF1 neurofibromin 1
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRIP3 nuclear receptor interacting protein 3
NRXN3 neurexin 3
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PART1 prostate androgen-regulated transcript 1 (non-protein coding)
PBX1 pre-B-cell leukemia homeobox 1
PCDHB17P protocadherin beta 17 pseudogene
PDE12 phosphodiesterase 12
PHF3 PHD finger protein 3
PHF8 PHD finger protein 8
PIGR polymeric immunoglobulin receptor
PLA2G5 phospholipase A2, group V
PPARA peroxisome proliferator-activated receptor alpha
PRB3 proline-rich protein BstNI subfamily 3
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RFPL3S RFPL3 antisense
RGS4 regulator of G-protein signaling 4
RIF1 replication timing regulatory factor 1
RPLP2 ribosomal protein, large, P2
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
SLC16A4 solute carrier family 16, member 4
SLCO1A2 solute carrier organic anion transporter family, member 1A2
SLIT3 slit homolog 3 (Drosophila)
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SP1 Sp1 transcription factor
SPATA2L spermatogenesis associated 2-like
STAB1 stabilin 1
TAS2R16 taste receptor, type 2, member 16
TBX5 T-box 5
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TFCP2L1 transcription factor CP2-like 1
TRAF3IP3 TRAF3 interacting protein 3
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TSPY1 testis specific protein, Y-linked 1
TTC12 tetratricopeptide repeat domain 12
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
ZNF235 zinc finger protein 235
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ACE angiotensin I converting enzyme
AKAP5 A kinase (PRKA) anchor protein 5
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ALG12 ALG12, alpha-1,6-mannosyltransferase
AMH anti-Mullerian hormone
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ANP32A-IT1 ANP32A intronic transcript 1
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARRB2 arrestin, beta 2
ASAP1-IT1 ASAP1 intronic transcript 1
ATG10 autophagy related 10
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
BMP15 bone morphogenetic protein 15
C22ORF29 chromosome 22 open reading frame 29
C3AR1 complement component 3a receptor 1
CD70 CD70 molecule
CD82 CD82 molecule
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNGB3 cyclic nucleotide gated channel beta 3
CNN1 calponin 1, basic, smooth muscle
CNTFR ciliary neurotrophic factor receptor
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DSPP dentin sialophosphoprotein
ELP6 elongator acetyltransferase complex subunit 6
EPN1 epsin 1
EYA3 EYA transcriptional coactivator and phosphatase 3
FBRS fibrosin
FBXO31 F-box protein 31
FLCN folliculin
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GRTP1 growth hormone regulated TBC protein 1
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
HIST1H3F histone cluster 1, H3f
HOXC4 homeobox C4
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
IL18R1 interleukin 18 receptor 1
IL22 interleukin 22
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KIAA0319L KIAA0319-like
KIFC3 kinesin family member C3
KLC2 kinesin light chain 2
KLF1 Kruppel-like factor 1 (erythroid)
KLHL28 kelch-like family member 28
LIFR leukemia inhibitory factor receptor alpha
LIME1 Lck interacting transmembrane adaptor 1
LMTK1 lemur tail kinase 1
LOXL3 lysyl oxidase-like 3
LRP4 low density lipoprotein receptor-related protein 4
LRRC2 leucine rich repeat containing 2
LY86 lymphocyte antigen 86
MAP3K7CL MAP3K7 C-terminal like
MFSD11 major facilitator superfamily domain containing 11
MMP9 matrix metallopeptidase 9
MRPL41 mitochondrial ribosomal protein L41
MXRA8 matrix-remodelling associated 8
MYLIP myosin regulatory light chain interacting protein
NGF nerve growth factor (beta polypeptide)
NOTCH1 notch 1
NPVF neuropeptide VF precursor
NT5M 5',3'-nucleotidase, mitochondrial
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OXCT2 3-oxoacid CoA transferase 2
PCDHA5 protocadherin alpha 5
PCDHGA10 protocadherin gamma subfamily A, 10
PDE8B phosphodiesterase 8B
PLBD1 phospholipase B domain containing 1
PRICKLE3 prickle homolog 3 (Drosophila)
PRSS22 protease, serine, 22
PSORS1C1 psoriasis susceptibility 1 candidate 1
PTPN7 protein tyrosine phosphatase, non-receptor type 7
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RPL10L ribosomal protein L10-like
RPS17P5 ribosomal protein S17 pseudogene 5
S100A3 S100 calcium binding protein A3
SCGB2A1 secretoglobin, family 2A, member 1
SIX3 SIX homeobox 3
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
TAGLN3 transgelin 3
TAS2R10 taste receptor, type 2, member 10
TBC1D8B TBC1 domain family, member 8B (with GRAM domain)
TCEAL2 transcription elongation factor A (SII)-like 2
THSD4 thrombospondin, type I, domain containing 4
TSPAN2 tetraspanin 2
TUBA4B tubulin, alpha 4b
VWA1 von Willebrand factor A domain containing 1
WDR62 WD repeat domain 62
ZIC3 Zic family member 3
ZMAT4 zinc finger, matrin-type 4
ZNF219 zinc finger protein 219
ZNF268 zinc finger protein 268
ZNF528 zinc finger protein 528
ZNF768 zinc finger protein 768