| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 4EGI-1 perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 4EGI-1_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.13454 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.104006 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.079904 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0624783 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0618217 |
| NAV2 | neuron navigator 2 | 0.0610698 |
| HDAC9 | histone deacetylase 9 | 0.0545984 |
| B2M | beta-2-microglobulin | 0.0469479 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0467191 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.046668 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0464569 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.046337 |
| CD44 | CD44 molecule (Indian blood group) | 0.0459682 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0456198 |
| APP | amyloid beta (A4) precursor protein | 0.0440018 |
| AUTS2 | autism susceptibility candidate 2 | 0.0423384 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0411129 |
| RND3 | Rho family GTPase 3 | 0.0410217 |
| SQSTM1 | sequestosome 1 | 0.0407327 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0393269 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0383118 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0348132 |
| CTSB | cathepsin B | 0.0343244 |
| GLIS3 | GLIS family zinc finger 3 | 0.0325639 |
| JMJD1C | jumonji domain containing 1C | 0.0320709 |
| SMYD3 | SET and MYND domain containing 3 | 0.0314856 |
| OPTN | optineurin | 0.0306682 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0301332 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0296475 |
| ERBIN | erbb2 interacting protein | 0.0289709 |
| MMP12 | matrix metallopeptidase 12 | 0.0286136 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0282851 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0273866 |
| SFTPA2 | surfactant protein A2 | 0.0266958 |
| DSG2 | desmoglein 2 | 0.0266579 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.026475 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0260956 |
| GPC6 | glypican 6 | 0.0259835 |
| BCL2L1 | BCL2-like 1 | 0.0251515 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0245887 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0237149 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0236305 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0236129 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0234851 |
| ANXA5 | annexin A5 | 0.0233079 |
| CDH13 | cadherin 13 | 0.0229415 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0224506 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0224219 |
| PRKCE | protein kinase C, epsilon | 0.0219971 |
| TM4SF19 | transmembrane 4 L six family member 19 | 0.0216929 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.021611 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.021577 |
| RPS3 | ribosomal protein S3 | 0.0213057 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0212876 |
| ANO6 | anoctamin 6 | 0.0207362 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0203497 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0202585 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.02019 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0199882 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0198065 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.019733 |
| DOCK9 | dedicator of cytokinesis 9 | 0.0197072 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0196622 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0196463 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0195343 |
| RPS2 | ribosomal protein S2 | 0.0193988 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0193011 |
| PCM1 | pericentriolar material 1 | 0.0190348 |
| BPTF | bromodomain PHD finger transcription factor | 0.0187805 |
| STC1 | stanniocalcin 1 | 0.0187588 |
| RASA2 | RAS p21 protein activator 2 | 0.0185845 |
| SMAD3 | SMAD family member 3 | 0.0185729 |
| FMNL2 | formin-like 2 | 0.018378 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0181901 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0181501 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0181297 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0181087 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0179366 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0179154 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0178308 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.017773 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0176408 |
| NLGN4Y | neuroligin 4, Y-linked | 0.0173944 |
| MT2A | metallothionein 2A | 0.0173755 |
| AXL | AXL receptor tyrosine kinase | 0.0173169 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0172827 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0171636 |
| CENPF | centromere protein F, 350/400kDa | 0.0170787 |
| CSTB | cystatin B (stefin B) | 0.0169719 |
| DSPP | dentin sialophosphoprotein | 0.0169242 |
| FNIP1 | folliculin interacting protein 1 | 0.016243 |
| ANKRD36 | ankyrin repeat domain 36 | 0.016156 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0161469 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0157724 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.015681 |
| DNMBP | dynamin binding protein | 0.0156607 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0156395 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0155749 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0154238 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0153106 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.306787 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.226052 |
| COL5A1 | collagen, type V, alpha 1 | -0.192219 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.184127 |
| TMSB10 | thymosin beta 10 | -0.163756 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.160803 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.156689 |
| LOX | lysyl oxidase | -0.135013 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.12038 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.115159 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.107085 |
| FN1 | fibronectin 1 | -0.101215 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0988278 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0962608 |
| VIM | vimentin | -0.0907595 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0878572 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0862933 |
| AHNAK | AHNAK nucleoprotein | -0.0848712 |
| SUCNR1 | succinate receptor 1 | -0.067395 |
| PRSS23 | protease, serine, 23 | -0.0673202 |
| NAV1 | neuron navigator 1 | -0.0672842 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0659215 |
| MAP1B | microtubule-associated protein 1B | -0.0624069 |
| LMNA | lamin A/C | -0.061863 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0616865 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0595197 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0578693 |
| DCLK2 | doublecortin-like kinase 2 | -0.0571289 |
| CANX | calnexin | -0.0567267 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0567259 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0561741 |
| MX2 | MX dynamin-like GTPase 2 | -0.0561669 |
| COL1A2 | collagen, type I, alpha 2 | -0.055028 |
| FBN1 | fibrillin 1 | -0.0543368 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0537769 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0531913 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0530349 |
| RIGI | RNA sensor RIG-I | -0.0484017 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0460344 |
| TAGLN2 | transgelin 2 | -0.0454661 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0447561 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0443175 |
| POTEF | POTE ankyrin domain family, member F | -0.0440853 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0434796 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0427531 |
| FLNB | filamin B, beta | -0.042727 |
| RRBP1 | ribosome binding protein 1 | -0.0418257 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0408478 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0406517 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0397206 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.0393347 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0384728 |
| PKM | pyruvate kinase, muscle | -0.0383618 |
| COL5A2 | collagen, type V, alpha 2 | -0.0377367 |
| PGK1 | phosphoglycerate kinase 1 | -0.0373553 |
| LRRC17 | leucine rich repeat containing 17 | -0.0357636 |
| LDHA | lactate dehydrogenase A | -0.0352182 |
| TENM3 | teneurin transmembrane protein 3 | -0.0348487 |
| COL3A1 | collagen, type III, alpha 1 | -0.0344712 |
| S100A10 | S100 calcium binding protein A10 | -0.0344183 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0340931 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0329891 |
| FSTL1 | follistatin-like 1 | -0.0327194 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | -0.0324669 |
| UBC | ubiquitin C | -0.032259 |
| CUX1 | cut-like homeobox 1 | -0.0320017 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0316922 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0312949 |
| HLA-C | major histocompatibility complex, class I, C | -0.0311617 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0310345 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0309463 |
| TPM1 | tropomyosin 1 (alpha) | -0.0308432 |
| RUNX1 | runt-related transcription factor 1 | -0.0305368 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0304334 |
| SPAG9 | sperm associated antigen 9 | -0.0301415 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0299196 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.0298869 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0297137 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0295549 |
| IL7R | interleukin 7 receptor | -0.0292172 |
| LOXL2 | lysyl oxidase-like 2 | -0.0290943 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0289554 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.028615 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.028517 |
| SP3 | Sp3 transcription factor | -0.0283784 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0281001 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0273603 |
| MEIS2 | Meis homeobox 2 | -0.0272979 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0272901 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0270046 |
| ACTN4 | actinin, alpha 4 | -0.0269661 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.026806 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0267753 |
| SYTL3 | synaptotagmin-like 3 | -0.026598 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0265909 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0264844 |
| HLA-B | major histocompatibility complex, class I, B | -0.0263659 |
| PTMA | prothymosin, alpha | -0.0263378 |
| PLAT | plasminogen activator, tissue | -0.0263248 |
| COL1A1 | collagen, type I, alpha 1 | -0.0261461 |
