| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 4EGI-1 perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 4EGI-1_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FRMD4A | FERM domain containing 4A | 0.202244 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.200124 |
| VIM | vimentin | 0.11936 |
| B2M | beta-2-microglobulin | 0.119118 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.103742 |
| CD44 | CD44 molecule (Indian blood group) | 0.092392 |
| NAV2 | neuron navigator 2 | 0.0908404 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0907795 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0894552 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0890661 |
| RND3 | Rho family GTPase 3 | 0.08639 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0825103 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0759553 |
| FNDC3B | fibronectin type III domain containing 3B | 0.073799 |
| VEGFA | vascular endothelial growth factor A | 0.0710944 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0681421 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0671048 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0627042 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0608722 |
| ANXA5 | annexin A5 | 0.0582865 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0567217 |
| MYADM | myeloid-associated differentiation marker | 0.0564541 |
| EGFR | epidermal growth factor receptor | 0.0550072 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0548386 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0527698 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0527101 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0522743 |
| OPTN | optineurin | 0.0521755 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0521156 |
| LDHA | lactate dehydrogenase A | 0.0502816 |
| GPC5 | glypican 5 | 0.0494116 |
| TPM3 | tropomyosin 3 | 0.0478152 |
| OSMR | oncostatin M receptor | 0.0435372 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0422876 |
| SFTPA2 | surfactant protein A2 | 0.0417997 |
| ATP13A3 | ATPase type 13A3 | 0.0410909 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0404542 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0402901 |
| SEPTIN9 | septin 9 | 0.0400353 |
| MT2A | metallothionein 2A | 0.0391631 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0389195 |
| MSN | moesin | 0.0381477 |
| CDCP1 | CUB domain containing protein 1 | 0.0374386 |
| COG5 | component of oligomeric golgi complex 5 | 0.0369949 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0365928 |
| RPS2 | ribosomal protein S2 | 0.0361022 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0358637 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0354985 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0348923 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0345583 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0340712 |
| MX1 | MX dynamin-like GTPase 1 | 0.0340525 |
| GPR176 | G protein-coupled receptor 176 | 0.0340171 |
| GOLGB1 | golgin B1 | 0.0339014 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0328776 |
| APP | amyloid beta (A4) precursor protein | 0.0322291 |
| DSPP | dentin sialophosphoprotein | 0.0317718 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0313 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0311241 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0310747 |
| TAOK1 | TAO kinase 1 | 0.030205 |
| ADAR | adenosine deaminase, RNA-specific | 0.030153 |
| MSR1 | macrophage scavenger receptor 1 | 0.0300738 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0296569 |
| PLEC | plectin | 0.029513 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.029411 |
| RPL3 | ribosomal protein L3 | 0.0293346 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0283261 |
| ARRDC3 | arrestin domain containing 3 | 0.028256 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0280638 |
| SLC22A3 | solute carrier family 22 (organic cation transporter), member 3 | 0.0279816 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0278104 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0276612 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0274458 |
| ITSN2 | intersectin 2 | 0.0273758 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0271687 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0269657 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0269199 |
| UBC | ubiquitin C | 0.0266554 |
| RAI14 | retinoic acid induced 14 | 0.0260868 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0259709 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0259614 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0251748 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0251327 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0250011 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0249492 |
| EHBP1 | EH domain binding protein 1 | 0.0249017 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0248876 |
| RPL7 | ribosomal protein L7 | 0.0248149 |
| PLK2 | polo-like kinase 2 | 0.0246874 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | 0.0242688 |
| RPL12 | ribosomal protein L12 | 0.0241507 |
| WASL | Wiskott-Aldrich syndrome-like | 0.024093 |
| JMJD1C | jumonji domain containing 1C | 0.0239293 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0239233 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0238427 |
| HIPK3 | homeodomain interacting protein kinase 3 | 0.0237334 |
| LYST | lysosomal trafficking regulator | 0.0236485 |
| PCBP3 | poly(rC) binding protein 3 | 0.0232953 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0232913 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | -0.263562 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.239974 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0991286 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0928575 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.0887081 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0868617 |
| RRBP1 | ribosome binding protein 1 | -0.0815613 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0788395 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0762672 |
| GPC6 | glypican 6 | -0.0731769 |
| TXNRD1 | thioredoxin reductase 1 | -0.0720585 |
| TMSB10 | thymosin beta 10 | -0.0662624 |
| GLIS3 | GLIS family zinc finger 3 | -0.0585606 |
| CSF1 | colony stimulating factor 1 (macrophage) | -0.05852 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0555079 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0545291 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0502599 |
| DIAPH3 | diaphanous-related formin 3 | -0.0496561 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0495472 |
| CP | ceruloplasmin (ferroxidase) | -0.0477942 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0477738 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0472051 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0467717 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0457209 |
| FTL | ferritin, light polypeptide | -0.0455178 |
| PTMA | prothymosin, alpha | -0.0449372 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0438895 |
| NFIB | nuclear factor I/B | -0.0432359 |
| RBM39 | RNA binding motif protein 39 | -0.0416502 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0410067 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0404668 |
| GNAS | GNAS complex locus | -0.0382653 |
| ANLN | anillin, actin binding protein | -0.038001 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0379016 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0369623 |
| RRM2 | ribonucleotide reductase M2 | -0.0367185 |
| RHEB | Ras homolog enriched in brain | -0.0361958 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0350962 |
| SDCBP | syndecan binding protein (syntenin) | -0.0350586 |
| HMGB1 | high mobility group box 1 | -0.0349543 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0341962 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0340043 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | -0.0338553 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0334035 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0333864 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0330507 |
| NDRG1 | N-myc downstream regulated 1 | -0.0322457 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0321598 |
| FUS | FUS RNA binding protein | -0.0319184 |
| CD70 | CD70 molecule | -0.031677 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0312317 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.030654 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0303875 |
| FRMD5 | FERM domain containing 5 | -0.0301262 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0300574 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0300504 |
| TMEM263 | transmembrane protein 263 | -0.0297562 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0297173 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0297147 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0293283 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0292341 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0291606 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0290706 |
| DENND2B | DENN domain containing 2B | -0.0290063 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.0282871 |
| TCEA1 | transcription elongation factor A (SII), 1 | -0.0282591 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0279157 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0278424 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0275607 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0273647 |
| PFN1 | profilin 1 | -0.027265 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0272491 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0271641 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0270829 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0269776 |
| GDF15 | growth differentiation factor 15 | -0.0268244 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0267483 |
| CAVIN1 | caveolae associated protein 1 | -0.0266328 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0266184 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -0.0264409 |
| ANKRD11 | ankyrin repeat domain 11 | -0.026246 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0259739 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0259485 |
| HKDC1 | hexokinase domain containing 1 | -0.0258698 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0258629 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0255765 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | -0.0254209 |
| ANXA4 | annexin A4 | -0.0252602 |
| ACTN4 | actinin, alpha 4 | -0.0251929 |
| PTGR1 | prostaglandin reductase 1 | -0.0251585 |
| CBX3 | chromobox homolog 3 | -0.0249222 |
| NOP58 | NOP58 ribonucleoprotein | -0.0249124 |
| HMGB2 | high mobility group box 2 | -0.0248886 |
| MAP1B | microtubule-associated protein 1B | -0.0248646 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.0247003 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0246631 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0244305 |
| LDHB | lactate dehydrogenase B | -0.0241294 |
| LAPTM4A | lysosomal protein transmembrane 4 alpha | -0.0238794 |
| MORF4L2 | mortality factor 4 like 2 | -0.0238622 |
