| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 4EGI-1 perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 4EGI-1_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MEST | mesoderm specific transcript | 0.371589 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.147845 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.130761 |
| VIM | vimentin | 0.124348 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.097347 |
| VEGFA | vascular endothelial growth factor A | 0.0958961 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.089912 |
| HMGA2 | high mobility group AT-hook 2 | 0.0769559 |
| CADM2 | cell adhesion molecule 2 | 0.0755454 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0664756 |
| ENO1 | enolase 1, (alpha) | 0.0660078 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0636361 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0622619 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0618669 |
| UTRN | utrophin | 0.056703 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0546155 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0538592 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0526327 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0510998 |
| UBC | ubiquitin C | 0.0497835 |
| GSE1 | Gse1 coiled-coil protein | 0.0497683 |
| EGFR | epidermal growth factor receptor | 0.0489101 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.048783 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0441377 |
| METTL15 | methyltransferase like 15 | 0.0436894 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0420067 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0403857 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0398272 |
| RPS2 | ribosomal protein S2 | 0.0390708 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.038572 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0378088 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0370634 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0369043 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0364683 |
| PCDH7 | protocadherin 7 | 0.0361412 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0349576 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0344042 |
| EGR1 | early growth response 1 | 0.0334965 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0330776 |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) | 0.0327633 |
| VCL | vinculin | 0.032598 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0325451 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0325035 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0324739 |
| MYOF | myoferlin | 0.0322552 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0315636 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0313944 |
| GPHN | gephyrin | 0.0313393 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0311462 |
| RPL3 | ribosomal protein L3 | 0.0308051 |
| RACK1 | receptor for activated C kinase 1 | 0.0302566 |
| RPS4X | ribosomal protein S4, X-linked | 0.0302341 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0302288 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0301793 |
| DST | dystonin | 0.0299808 |
| VMP1 | vacuole membrane protein 1 | 0.0299429 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0296651 |
| SFTPA2 | surfactant protein A2 | 0.0292861 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0289299 |
| SEM1 | SEM1 26S proteasome subunit | 0.0288685 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | 0.0283472 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0278377 |
| COPA | coatomer protein complex, subunit alpha | 0.0274971 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0273263 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0268826 |
| EXOC6B | exocyst complex component 6B | 0.0268776 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | 0.0268568 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0266468 |
| RAD51B | RAD51 paralog B | 0.0264792 |
| RPS12 | ribosomal protein S12 | 0.0263909 |
| POTEF | POTE ankyrin domain family, member F | 0.0262949 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.0261847 |
| PKM | pyruvate kinase, muscle | 0.0260974 |
| PCBP2 | poly(rC) binding protein 2 | 0.0259897 |
| SIK3 | SIK family kinase 3 | 0.0258839 |
| MED13 | mediator complex subunit 13 | 0.0257306 |
| THBS1 | thrombospondin 1 | 0.0255727 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0255075 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0254933 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0253824 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0251315 |
| FOXP1 | forkhead box P1 | 0.0248874 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0248295 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0244083 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | 0.0243026 |
| CLIC4 | chloride intracellular channel 4 | 0.024289 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | 0.0242264 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0237426 |
| CDK6 | cyclin-dependent kinase 6 | 0.0237131 |
| INTS6 | integrator complex subunit 6 | 0.023357 |
| MYO9A | myosin IXA | 0.0232634 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0230463 |
| BPTF | bromodomain PHD finger transcription factor | 0.0230233 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0230196 |
| ITGAV | integrin, alpha V | 0.0229547 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0229248 |
| PARD3 | par-3 family cell polarity regulator | 0.0228149 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0227997 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0227934 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0226931 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PEG10 | paternally expressed 10 | -0.146124 |
| CENPF | centromere protein F, 350/400kDa | -0.0935147 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0744763 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0654405 |
| NFIB | nuclear factor I/B | -0.0575977 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0566852 |
| MGP | matrix Gla protein | -0.0553513 |
| PTMA | prothymosin, alpha | -0.054406 |
| ZFHX3 | zinc finger homeobox 3 | -0.053007 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0523577 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0489591 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0449199 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0447448 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0445568 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0430961 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0409472 |
| COL1A2 | collagen, type I, alpha 2 | -0.0403422 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0401923 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.040028 |
| FLNB | filamin B, beta | -0.0394177 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0393072 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.037556 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0375469 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0368774 |
| KIF20B | kinesin family member 20B | -0.0368459 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.0355744 |
| SOBP | sine oculis binding protein homolog (Drosophila) | -0.0345541 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.034367 |
| IGF2R | insulin-like growth factor 2 receptor | -0.0335885 |
| TPK1 | thiamin pyrophosphokinase 1 | -0.0329188 |
| RNF130 | ring finger protein 130 | -0.0328341 |
| MEOX2 | mesenchyme homeobox 2 | -0.0323475 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0320011 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0318168 |
| RSU1 | Ras suppressor protein 1 | -0.0317111 |
| PRLR | prolactin receptor | -0.0309905 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0309608 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0306661 |
| NFIA | nuclear factor I/A | -0.0306498 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0305906 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0305367 |
| MED13L | mediator complex subunit 13-like | -0.0303359 |
| TET2 | tet methylcytosine dioxygenase 2 | -0.0301234 |
| DIAPH3 | diaphanous-related formin 3 | -0.029934 |
| TMEM41B | transmembrane protein 41B | -0.0296275 |
| RBM25 | RNA binding motif protein 25 | -0.0291125 |
| SEPTIN7 | septin 7 | -0.0289292 |
| RHEB | Ras homolog enriched in brain | -0.0286896 |
| RPL35A | ribosomal protein L35a | -0.0284472 |
| HELZ | helicase with zinc finger | -0.0282909 |
| QKI | QKI, KH domain containing, RNA binding | -0.0282757 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.0281607 |
| PLS3 | plastin 3 | -0.028036 |
| INSIG2 | insulin induced gene 2 | -0.0279611 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0278968 |
| SEPTIN11 | septin 11 | -0.0278841 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.027778 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0276561 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.027613 |
| IER3 | immediate early response 3 | -0.0275611 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0273333 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0272743 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.0263806 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0263503 |
| CENPE | centromere protein E, 312kDa | -0.0261154 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0260257 |
| CREM | cAMP responsive element modulator | -0.0259109 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0258753 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0257423 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0254683 |
| TMSB10 | thymosin beta 10 | -0.0252734 |
| TET1 | tet methylcytosine dioxygenase 1 | -0.0248176 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0247756 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0246866 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0246067 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0246013 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0244901 |
| HMGB2 | high mobility group box 2 | -0.0244535 |
| KIF11 | kinesin family member 11 | -0.0243986 |
| NHSL1 | NHS-like 1 | -0.0242224 |
| GAS2L3 | growth arrest-specific 2 like 3 | -0.0239876 |
| JAM3 | junctional adhesion molecule 3 | -0.0239211 |
| PGK1 | phosphoglycerate kinase 1 | -0.0237311 |
| GNG2 | guanine nucleotide binding protein (G protein), gamma 2 | -0.0236891 |
| MTDH | metadherin | -0.0236307 |
| PRELID2 | PRELI domain containing 2 | -0.0234796 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0232194 |
| CLMP | CXADR-like membrane protein | -0.023153 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | -0.0227215 |
| MAP1B | microtubule-associated protein 1B | -0.0224454 |
| RBM27 | RNA binding motif protein 27 | -0.0223319 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 | -0.0221979 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0221636 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0221212 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0220471 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0219422 |
| BUB3 | BUB3 mitotic checkpoint protein | -0.0218673 |
| RFX7 | regulatory factor X, 7 | -0.0217789 |
| BRD8 | bromodomain containing 8 | -0.0217553 |
| RRBP1 | ribosome binding protein 1 | -0.0217552 |
