| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 4EGI-1 perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 4EGI-1_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.123102 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.114909 |
| EGFR | epidermal growth factor receptor | 0.106874 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0795971 |
| EFNA5 | ephrin-A5 | 0.0769878 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0751691 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0640052 |
| BMP6 | bone morphogenetic protein 6 | 0.0621658 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0620283 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0611272 |
| HMGA2 | high mobility group AT-hook 2 | 0.0594736 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0588507 |
| MCL1 | myeloid cell leukemia 1 | 0.0546494 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0532182 |
| DSPP | dentin sialophosphoprotein | 0.0527178 |
| TGM2 | transglutaminase 2 | 0.0513767 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0505916 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0501568 |
| FMNL2 | formin-like 2 | 0.0498272 |
| LAMC2 | laminin, gamma 2 | 0.0491351 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0490477 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0472919 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0471509 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.046926 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0463823 |
| RASAL2 | RAS protein activator like 2 | 0.0456054 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.044946 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0442425 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0441519 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.0431696 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0421259 |
| SEPTIN9 | septin 9 | 0.0419508 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0417519 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0412022 |
| SMAD3 | SMAD family member 3 | 0.0407489 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0402681 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.039145 |
| PLEC | plectin | 0.0379463 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0371453 |
| SGMS2 | sphingomyelin synthase 2 | 0.0365052 |
| RCOR1 | REST corepressor 1 | 0.0363091 |
| RUNX1 | runt-related transcription factor 1 | 0.0354548 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0351591 |
| CLMP | CXADR-like membrane protein | 0.034627 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0344745 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0344329 |
| INTS6 | integrator complex subunit 6 | 0.0343824 |
| MMP1 | matrix metallopeptidase 1 | 0.0342177 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0340854 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.0329847 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0327699 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.0322909 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.031586 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0313367 |
| OSMR | oncostatin M receptor | 0.0309534 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0287997 |
| DIAPH1 | diaphanous-related formin 1 | 0.0285822 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.02855 |
| FLNB | filamin B, beta | 0.0282609 |
| CDCP1 | CUB domain containing protein 1 | 0.02784 |
| BCL2L1 | BCL2-like 1 | 0.0278214 |
| NDRG1 | N-myc downstream regulated 1 | 0.0277794 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0277323 |
| MSN | moesin | 0.0272094 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0269113 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0266095 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.0265978 |
| MED13L | mediator complex subunit 13-like | 0.0263962 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0263131 |
| CD44 | CD44 molecule (Indian blood group) | 0.0256058 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0252215 |
| STRIP2 | striatin interacting protein 2 | 0.0252184 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0249355 |
| RAB31 | RAB31, member RAS oncogene family | 0.0240673 |
| CREBBP | CREB binding protein | 0.0236845 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.02336 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0231324 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0229411 |
| EXOC6B | exocyst complex component 6B | 0.0229322 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0222356 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0221454 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0220799 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0220046 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0218257 |
| RAB10 | RAB10, member RAS oncogene family | 0.0217237 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0213981 |
| MYO5B | myosin VB | 0.0211938 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.021188 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0204407 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0198759 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0192759 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0192198 |
| MYO1E | myosin IE | 0.0191625 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0191119 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0189927 |
| TMEM164 | transmembrane protein 164 | 0.0189247 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0188953 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0187326 |
| STC1 | stanniocalcin 1 | 0.0186911 |
| GATAD2A | GATA zinc finger domain containing 2A | 0.0186894 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.210777 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.112589 |
| LAMB3 | laminin, beta 3 | -0.110943 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.0994555 |
| PTMA | prothymosin, alpha | -0.0945831 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.0860653 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0821517 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0779167 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0652712 |
| LMO7 | LIM domain 7 | -0.0650973 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0613701 |
| GOLGA4 | golgin A4 | -0.0597565 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0528811 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0526201 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0521579 |
| S100A6 | S100 calcium binding protein A6 | -0.0514536 |
| LMTK2 | lemur tyrosine kinase 2 | -0.051005 |
| PGK1 | phosphoglycerate kinase 1 | -0.0509766 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0504216 |
| FTL | ferritin, light polypeptide | -0.0502733 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0498872 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0496003 |
| RRBP1 | ribosome binding protein 1 | -0.049355 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0473764 |
| S100A10 | S100 calcium binding protein A10 | -0.0458301 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0438263 |
| RPL35A | ribosomal protein L35a | -0.0422004 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0420582 |
| S100A4 | S100 calcium binding protein A4 | -0.0416235 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.041576 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0415219 |
| GNAS | GNAS complex locus | -0.0414858 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0408933 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0388147 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.038193 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0374012 |
| B2M | beta-2-microglobulin | -0.0372808 |
| CD2AP | CD2-associated protein | -0.0369278 |
| VIM | vimentin | -0.0365684 |
| RBM39 | RNA binding motif protein 39 | -0.036567 |
| PLAUR | plasminogen activator, urokinase receptor | -0.036435 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0362874 |
| RPL34 | ribosomal protein L34 | -0.036002 |
| CALU | calumenin | -0.035875 |
| SDC4 | syndecan 4 | -0.0358097 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0355652 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.0353158 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0352533 |
| HMGA1 | high mobility group AT-hook 1 | -0.0350501 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.034765 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0333195 |
| MTDH | metadherin | -0.0324832 |
| RPLP1 | ribosomal protein, large, P1 | -0.0308032 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0304763 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.030415 |
| RPL30 | ribosomal protein L30 | -0.0302142 |
| SLMAP | sarcolemma associated protein | -0.0300334 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0299956 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.029863 |
| FAM107B | family with sequence similarity 107, member B | -0.029665 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0291446 |
| RPL11 | ribosomal protein L11 | -0.0286849 |
| TXNIP | thioredoxin interacting protein | -0.0285811 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0284915 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0283554 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0283083 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0280535 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0279677 |
| PERP | PERP, TP53 apoptosis effector | -0.0277307 |
| RPS21 | ribosomal protein S21 | -0.027593 |
| NOP58 | NOP58 ribonucleoprotein | -0.0275665 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0273717 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0272072 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0271666 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0271425 |
| SQSTM1 | sequestosome 1 | -0.0270779 |
| THOC2 | THO complex 2 | -0.0269425 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0267077 |
| RBM25 | RNA binding motif protein 25 | -0.0265782 |
| EPCAM | epithelial cell adhesion molecule | -0.0262866 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0260596 |
| TAOK3 | TAO kinase 3 | -0.0259422 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0258752 |
| IER3 | immediate early response 3 | -0.0257896 |
| RPS27A | ribosomal protein S27a | -0.0251428 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0251063 |
| RPS24 | ribosomal protein S24 | -0.0250638 |
| ZNF292 | zinc finger protein 292 | -0.0248948 |
| TMEM263 | transmembrane protein 263 | -0.024858 |
| NPSR1 | neuropeptide S receptor 1 | -0.0248074 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.024623 |
| SEPTIN7 | septin 7 | -0.0245529 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0245463 |
| EMP1 | epithelial membrane protein 1 | -0.0245453 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0244602 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0243811 |
| RPL12 | ribosomal protein L12 | -0.0242926 |
| FAM3C | family with sequence similarity 3, member C | -0.0241175 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0240841 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0240769 |
