| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 4EGI-1 perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 4EGI-1_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NEBL | nebulette | 0.151297 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.122365 |
| TENM3 | teneurin transmembrane protein 3 | 0.109162 |
| ZNF608 | zinc finger protein 608 | 0.0904597 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0898129 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.086308 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0832464 |
| COL5A2 | collagen, type V, alpha 2 | 0.0782181 |
| VCL | vinculin | 0.0757907 |
| SMYD3 | SET and MYND domain containing 3 | 0.0736624 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0735599 |
| JMJD1C | jumonji domain containing 1C | 0.0694045 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0683122 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0661795 |
| AUTS2 | autism susceptibility candidate 2 | 0.0650949 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0633007 |
| DST | dystonin | 0.0611845 |
| VMP1 | vacuole membrane protein 1 | 0.061036 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0608188 |
| WLS | wntless Wnt ligand secretion mediator | 0.059448 |
| ATP11A | ATPase, class VI, type 11A | 0.0544555 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0500893 |
| DENND1A | DENN/MADD domain containing 1A | 0.0498139 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0485262 |
| BNC2 | basonuclin 2 | 0.048267 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0473818 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0455115 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0454346 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0442029 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0429212 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0423262 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0419954 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0416611 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0414364 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0411076 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0405447 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0404519 |
| CENPF | centromere protein F, 350/400kDa | 0.0402139 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0401652 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0394597 |
| NF1 | neurofibromin 1 | 0.0387699 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0383168 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0378803 |
| SIK3 | SIK family kinase 3 | 0.0376564 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0364526 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0357595 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0356779 |
| USP34 | ubiquitin specific peptidase 34 | 0.0354506 |
| DOCK3 | dedicator of cytokinesis 3 | 0.0353574 |
| SKIL | SKI-like proto-oncogene | 0.0352041 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0348233 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0348232 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0347165 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0337218 |
| EXOC4 | exocyst complex component 4 | 0.0336978 |
| AEBP2 | AE binding protein 2 | 0.0334425 |
| PCM1 | pericentriolar material 1 | 0.0327811 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0325879 |
| NBEA | neurobeachin | 0.0324737 |
| PCBP2 | poly(rC) binding protein 2 | 0.0323829 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0321861 |
| KIAA1328 | KIAA1328 | 0.0321397 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.032109 |
| ZNF638 | zinc finger protein 638 | 0.0318065 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0313953 |
| RPL3 | ribosomal protein L3 | 0.0313368 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0311198 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0309942 |
| ZNF407 | zinc finger protein 407 | 0.0309388 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0308765 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0308552 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0308153 |
| WWOX | WW domain containing oxidoreductase | 0.0306865 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0306438 |
| ENO1 | enolase 1, (alpha) | 0.0305128 |
| ENAH | enabled homolog (Drosophila) | 0.0302592 |
| CUX1 | cut-like homeobox 1 | 0.0302568 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) | 0.0300559 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0298166 |
| EXOC6B | exocyst complex component 6B | 0.0297114 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.029708 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0295957 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0295948 |
| ZNF609 | zinc finger protein 609 | 0.0295771 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0295301 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0294759 |
| RCOR1 | REST corepressor 1 | 0.0294576 |
| NFIB | nuclear factor I/B | 0.029225 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0291788 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0290062 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0289497 |
| ST3GAL3 | ST3 beta-galactoside alpha-2,3-sialyltransferase 3 | 0.0288985 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0282647 |
| GSE1 | Gse1 coiled-coil protein | 0.028223 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0281547 |
| TBL1X | transducin (beta)-like 1X-linked | 0.0279033 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0278514 |
| TAOK1 | TAO kinase 1 | 0.0275341 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0273931 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0272438 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.122714 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0874067 |
| PTMA | prothymosin, alpha | -0.068319 |
| TMSB10 | thymosin beta 10 | -0.0523267 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0454013 |
| RPS8 | ribosomal protein S8 | -0.0441908 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0430778 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | -0.0420098 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0419729 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0409793 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0381582 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0375715 |
| RPS6 | ribosomal protein S6 | -0.0346957 |
| WDR45B | WD repeat domain 45B | -0.0346141 |
| SOX2 | SRY (sex determining region Y)-box 2 | -0.0345061 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0340353 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0333575 |
| RPS19 | ribosomal protein S19 | -0.0331257 |
| RPLP1 | ribosomal protein, large, P1 | -0.0328797 |
| RPS24 | ribosomal protein S24 | -0.0326234 |
| RPS29 | ribosomal protein S29 | -0.0325823 |
| RPL23 | ribosomal protein L23 | -0.0315622 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0309738 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0307753 |
| RPL19 | ribosomal protein L19 | -0.0305655 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0303426 |
| RPL26 | ribosomal protein L26 | -0.0301541 |
| RPL12 | ribosomal protein L12 | -0.0293839 |
| RBM25 | RNA binding motif protein 25 | -0.0287804 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0282727 |
| RPL36 | ribosomal protein L36 | -0.0279965 |
| RPS5 | ribosomal protein S5 | -0.0274411 |
| RPL34 | ribosomal protein L34 | -0.0272185 |
| RPLP2 | ribosomal protein, large, P2 | -0.0266751 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0259719 |
| GRID2 | glutamate receptor, ionotropic, delta 2 | -0.0251501 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0251047 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0244802 |
| HMGB1 | high mobility group box 1 | -0.024058 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0231912 |
| RPL32 | ribosomal protein L32 | -0.0231264 |
| RPS23 | ribosomal protein S23 | -0.0230746 |
| RPL35A | ribosomal protein L35a | -0.0229801 |
| RPS12 | ribosomal protein S12 | -0.0228323 |
| NOP58 | NOP58 ribonucleoprotein | -0.0226903 |
| RPS11 | ribosomal protein S11 | -0.022618 |
| RPL11 | ribosomal protein L11 | -0.0225846 |
| FTL | ferritin, light polypeptide | -0.0223694 |
| RPL37A | ribosomal protein L37a | -0.0220669 |
| RPL36A | ribosomal protein L36a | -0.0218961 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.021819 |
| YBX1 | Y box binding protein 1 | -0.021764 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0216876 |
| RPL31 | ribosomal protein L31 | -0.0214841 |
| RPS16 | ribosomal protein S16 | -0.0213961 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0211717 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.0210898 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0209129 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0206756 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0206091 |
| TUBB | tubulin, beta class I | -0.0205146 |
| RPS27A | ribosomal protein S27a | -0.0204538 |
| FAM162A | family with sequence similarity 162, member A | -0.0204473 |
| RPS14 | ribosomal protein S14 | -0.0201402 |
| RBM39 | RNA binding motif protein 39 | -0.0195463 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0193983 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0189643 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0189583 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0189393 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.018514 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -0.0184836 |
| RPS21 | ribosomal protein S21 | -0.0182898 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0181357 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.0180976 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0178195 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | -0.0177109 |
| RAB2A | RAB2A, member RAS oncogene family | -0.017304 |
| RHEB | Ras homolog enriched in brain | -0.0172458 |
| RAD51B | RAD51 paralog B | -0.016996 |
| RPS25 | ribosomal protein S25 | -0.0169187 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0169145 |
| RPL35 | ribosomal protein L35 | -0.016911 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0168648 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0168553 |
| TPD52 | tumor protein D52 | -0.0167868 |
| GOLGA4 | golgin A4 | -0.0167847 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0166605 |
| RACK1 | receptor for activated C kinase 1 | -0.0166046 |
| EGR1 | early growth response 1 | -0.0164324 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0161472 |
| TMEM41B | transmembrane protein 41B | -0.0161227 |
| FOXO3 | forkhead box O3 | -0.0160802 |
| EFNA5 | ephrin-A5 | -0.016054 |
| CAVIN1 | caveolae associated protein 1 | -0.0160111 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0159389 |
| RPL38 | ribosomal protein L38 | -0.0158855 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0157953 |
| RPL28 | ribosomal protein L28 | -0.0156112 |
| RPL8 | ribosomal protein L8 | -0.0155168 |
| DDX18 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | -0.015475 |
