| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 4EGI-1 perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 4EGI-1_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.112992 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0791563 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0724112 |
| ACTG1 | actin gamma 1 | 0.053409 |
| NAV2 | neuron navigator 2 | 0.0449147 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0441526 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.040621 |
| FMN1 | formin 1 | 0.0383074 |
| INTS6 | integrator complex subunit 6 | 0.0361957 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0360279 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0346502 |
| LRRC23 | leucine rich repeat containing 23 | 0.0340189 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0329582 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0311085 |
| APP | amyloid beta (A4) precursor protein | 0.0310943 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.030573 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.029256 |
| CUX1 | cut-like homeobox 1 | 0.0281168 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0269403 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0263086 |
| MYO1E | myosin IE | 0.026045 |
| ANO6 | anoctamin 6 | 0.0258535 |
| TLE4 | transducin-like enhancer of split 4 | 0.0252845 |
| ACTN1 | actinin, alpha 1 | 0.0248685 |
| TBC1D22A | TBC1 domain family, member 22A | 0.024773 |
| EXOC4 | exocyst complex component 4 | 0.0237709 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0228353 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0228132 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0224399 |
| VCL | vinculin | 0.0220447 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0218289 |
| SHISA5 | shisa family member 5 | 0.021713 |
| UTRN | utrophin | 0.0216717 |
| PRKCE | protein kinase C, epsilon | 0.0216491 |
| GPC6 | glypican 6 | 0.0206322 |
| EFCAB13 | EF-hand calcium binding domain 13 | 0.0205748 |
| SECISBP2 | SECIS binding protein 2 | 0.020446 |
| EGR1 | early growth response 1 | 0.0203853 |
| SQSTM1 | sequestosome 1 | 0.0203213 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0202908 |
| DST | dystonin | 0.0202066 |
| SETBP1 | SET binding protein 1 | 0.0197136 |
| SEPTIN9 | septin 9 | 0.0197126 |
| KDM3B | lysine (K)-specific demethylase 3B | 0.0196111 |
| ADORA1 | adenosine A1 receptor | 0.0194924 |
| MCL1 | myeloid cell leukemia 1 | 0.0194634 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0194048 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0193627 |
| EHBP1 | EH domain binding protein 1 | 0.0193152 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0189665 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0187869 |
| GOLGB1 | golgin B1 | 0.018732 |
| NAV1 | neuron navigator 1 | 0.0186297 |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 | 0.0185053 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0184297 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | 0.0183334 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.018173 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0180734 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0180176 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0179149 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0178134 |
| HMGA2 | high mobility group AT-hook 2 | 0.0177022 |
| METTL2B | methyltransferase like 2B | 0.0176177 |
| DENND1A | DENN/MADD domain containing 1A | 0.0174187 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0174149 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0172182 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.0171968 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0170807 |
| MYO9A | myosin IXA | 0.0168799 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0166764 |
| CCDC138 | coiled-coil domain containing 138 | 0.0165253 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0164592 |
| USP34 | ubiquitin specific peptidase 34 | 0.0163421 |
| AEBP2 | AE binding protein 2 | 0.0162506 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0162351 |
| RASA3 | RAS p21 protein activator 3 | 0.016201 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0160741 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | 0.0159871 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0157911 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0157259 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0157152 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0156951 |
| PAX3 | paired box 3 | 0.0156936 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0156446 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.0154097 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0152818 |
| SKI | SKI proto-oncogene | 0.0152407 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0152347 |
| GPATCH2L | G patch domain containing 2-like | 0.0152293 |
| PDE10A | phosphodiesterase 10A | 0.0152261 |
| PILRA | paired immunoglobin-like type 2 receptor alpha | 0.0151873 |
| SOX13 | SRY (sex determining region Y)-box 13 | 0.0151426 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0150818 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0150404 |
| TEX14 | testis expressed 14 | 0.0150364 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0149181 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0148359 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0148012 |
| COMMD10 | COMM domain containing 10 | 0.0147178 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0147026 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.163454 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.159687 |
| VGF | VGF nerve growth factor inducible | -0.106799 |
| NDRG1 | N-myc downstream regulated 1 | -0.102251 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0976015 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0946452 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0872686 |
| TMSB10 | thymosin beta 10 | -0.0839795 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.080674 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0784896 |
| S100A6 | S100 calcium binding protein A6 | -0.0740413 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0719866 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0714812 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.070814 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0688599 |
| TAGLN2 | transgelin 2 | -0.064974 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.064007 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0622992 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0611333 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0552208 |
| DCT | dopachrome tautomerase | -0.0521914 |
| INSIG1 | insulin induced gene 1 | -0.0502401 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0488917 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0485631 |
| PTMA | prothymosin, alpha | -0.0474736 |
| PGK1 | phosphoglycerate kinase 1 | -0.0473424 |
| RNF145 | ring finger protein 145 | -0.0470674 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.0462544 |
| NUP58 | nucleoporin 58 | -0.0451361 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0440716 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0423288 |
| WDR45B | WD repeat domain 45B | -0.0420368 |
| MT2A | metallothionein 2A | -0.0420291 |
| CD109 | CD109 molecule | -0.04157 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0410086 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0408438 |
| RNF24 | ring finger protein 24 | -0.0407986 |
| GNAS | GNAS complex locus | -0.0406564 |
| NLGN1 | neuroligin 1 | -0.040496 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.040319 |
| HLA-B | major histocompatibility complex, class I, B | -0.0400076 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0399407 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0398258 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0397931 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0396997 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.039401 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -0.0388498 |
| RFX7 | regulatory factor X, 7 | -0.0386187 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0384718 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0383556 |
| RTN4 | reticulon 4 | -0.0379562 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.0365392 |
| CALD1 | caldesmon 1 | -0.0360603 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0359742 |
| MT1X | metallothionein 1X | -0.0349217 |
| ZNF292 | zinc finger protein 292 | -0.0348031 |
| PHF21A | PHD finger protein 21A | -0.0346844 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0346037 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0345726 |
| SETD5 | SET domain containing 5 | -0.0338056 |
| NBAS | neuroblastoma amplified sequence | -0.033655 |
| MACROD2 | MACRO domain containing 2 | -0.0330571 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0326581 |
| TNNC1 | troponin C type 1 (slow) | -0.0326534 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0307136 |
| OXR1 | oxidation resistance 1 | -0.030576 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0302947 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0301292 |
| TFG | TRK-fused gene | -0.0300141 |
| PKM | pyruvate kinase, muscle | -0.0295901 |
| FOXJ3 | forkhead box J3 | -0.0294187 |
| FOSL1 | FOS-like antigen 1 | -0.0293988 |
| AHR | aryl hydrocarbon receptor | -0.0290696 |
| POTEF | POTE ankyrin domain family, member F | -0.0290445 |
| XPO1 | exportin 1 | -0.0290406 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0289062 |
| YBX1 | Y box binding protein 1 | -0.0289049 |
| COPA | coatomer protein complex, subunit alpha | -0.0279254 |
| MTPN | myotrophin | -0.0277498 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0276056 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0266388 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.0266102 |
| S100A10 | S100 calcium binding protein A10 | -0.0264262 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0261563 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0258725 |
| GDF15 | growth differentiation factor 15 | -0.0254745 |
| SRPK2 | SRSF protein kinase 2 | -0.0252418 |
| CABIN1 | calcineurin binding protein 1 | -0.0251889 |
| CDC73 | cell division cycle 73 | -0.0251723 |
| CSNK1E | casein kinase 1, epsilon | -0.0250403 |
| USP3 | ubiquitin specific peptidase 3 | -0.0249404 |
| MEF2A | myocyte enhancer factor 2A | -0.0249317 |
| COL1A2 | collagen, type I, alpha 2 | -0.0249101 |
| PFN1 | profilin 1 | -0.0245446 |
| FMNL2 | formin-like 2 | -0.0244107 |
| PTMS | parathymosin | -0.024339 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0242482 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0242145 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0241453 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 | -0.0240946 |
