| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 4EGI-1 perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 4EGI-1_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | 0.237375 |
| VCL | vinculin | 0.10277 |
| IGF2 | insulin-like growth factor 2 | 0.0852246 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0782263 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0766122 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.0711302 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0663944 |
| PLAT | plasminogen activator, tissue | 0.063865 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0606479 |
| LSAMP | limbic system-associated membrane protein | 0.058802 |
| ACTG1 | actin gamma 1 | 0.0575899 |
| FMN1 | formin 1 | 0.0568716 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0549427 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | 0.0535553 |
| VMP1 | vacuole membrane protein 1 | 0.0533012 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0526127 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0525529 |
| ITGA1 | integrin, alpha 1 | 0.0519848 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0519402 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0513805 |
| SYT1 | synaptotagmin I | 0.0503298 |
| BPTF | bromodomain PHD finger transcription factor | 0.049852 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0483342 |
| PDE10A | phosphodiesterase 10A | 0.0475849 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0470992 |
| PLPP1 | phospholipid phosphatase 1 | 0.0470442 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.046586 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0465147 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0455716 |
| KLHL13 | kelch-like family member 13 | 0.0449056 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0445688 |
| MEIS2 | Meis homeobox 2 | 0.0439765 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0435609 |
| GLCCI1 | glucocorticoid induced 1 | 0.0433538 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0421955 |
| ZNF804A | zinc finger protein 804A | 0.0412206 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0405954 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0403001 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0389932 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0382359 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | 0.038082 |
| DST | dystonin | 0.0378131 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0371125 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0368696 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0367158 |
| PRKCA | protein kinase C, alpha | 0.0353814 |
| AUTS2 | autism susceptibility candidate 2 | 0.0347398 |
| TPM4 | tropomyosin 4 | 0.0345394 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0338271 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0335502 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0334492 |
| CCDC57 | coiled-coil domain containing 57 | 0.0334181 |
| CADM2 | cell adhesion molecule 2 | 0.0331413 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0327842 |
| SP100 | SP100 nuclear antigen | 0.0322574 |
| UNC5C | unc-5 homolog C (C. elegans) | 0.0322524 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0322095 |
| STK38L | serine/threonine kinase 38 like | 0.0315435 |
| EFNA5 | ephrin-A5 | 0.0314459 |
| RIGI | RNA sensor RIG-I | 0.0313209 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0310833 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0309564 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0309303 |
| EGR1 | early growth response 1 | 0.0304892 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0300251 |
| DIAPH2 | diaphanous-related formin 2 | 0.0299888 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | 0.0296119 |
| MAPK10 | mitogen-activated protein kinase 10 | 0.0283264 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.028287 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0275698 |
| GAB2 | GRB2-associated binding protein 2 | 0.0273434 |
| SIK2 | salt-inducible kinase 2 | 0.0266967 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0264538 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0263803 |
| EXOC4 | exocyst complex component 4 | 0.026029 |
| THBS1 | thrombospondin 1 | 0.0259657 |
| AMOTL1 | angiomotin like 1 | 0.0257466 |
| RPS3 | ribosomal protein S3 | 0.0255566 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0254678 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0251893 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | 0.0248796 |
| DGKH | diacylglycerol kinase, eta | 0.0247428 |
| DNM3 | dynamin 3 | 0.0244663 |
| TCF12 | transcription factor 12 | 0.0243824 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0242318 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0240577 |
| TLE4 | transducin-like enhancer of split 4 | 0.0240416 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0239833 |
| FHIT | fragile histidine triad | 0.0234799 |
| DACH2 | dachshund family transcription factor 2 | 0.0234353 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0233569 |
| FRMD4A | FERM domain containing 4A | 0.0232039 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0231505 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0230405 |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 | 0.0228752 |
| ATRNL1 | attractin-like 1 | 0.0227318 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0226974 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0224602 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0221492 |
| RET | ret proto-oncogene | 0.0220851 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.164844 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.148481 |
| PTMA | prothymosin, alpha | -0.08409 |
| COL1A1 | collagen, type I, alpha 1 | -0.0561177 |
| H3-3B | H3.3 histone B | -0.0514447 |
| VIM | vimentin | -0.0509708 |
| TMSB10 | thymosin beta 10 | -0.0475758 |
| RPLP1 | ribosomal protein, large, P1 | -0.0470562 |
| RPL35A | ribosomal protein L35a | -0.0386281 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0324056 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0318261 |
| RPL23 | ribosomal protein L23 | -0.0313038 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0304234 |
| LMNA | lamin A/C | -0.0294485 |
| GOLGA4 | golgin A4 | -0.0279574 |
| RPL34 | ribosomal protein L34 | -0.0272683 |
| HELZ | helicase with zinc finger | -0.0267847 |
| RPL19 | ribosomal protein L19 | -0.0267486 |
| OGA | O-GlcNAcase | -0.0261623 |
| S100A6 | S100 calcium binding protein A6 | -0.026128 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0260969 |
| NDRG1 | N-myc downstream regulated 1 | -0.0256069 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0251985 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0244414 |
| WDR45B | WD repeat domain 45B | -0.0240109 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0240028 |
| ANXA2 | annexin A2 | -0.0233231 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0231913 |
| FNBP1 | formin binding protein 1 | -0.0231697 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0231001 |
| RPS21 | ribosomal protein S21 | -0.0226064 |
| CCDC47 | coiled-coil domain containing 47 | -0.0225089 |
| FAM13A | family with sequence similarity 13, member A | -0.0224021 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0221392 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0219817 |
| RPL38 | ribosomal protein L38 | -0.0218782 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0215731 |
| RPS20 | ribosomal protein S20 | -0.0214304 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0213121 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0207614 |
| HMGB2 | high mobility group box 2 | -0.0205576 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0205026 |
| XPO1 | exportin 1 | -0.0204243 |
| PKM | pyruvate kinase, muscle | -0.0201948 |
| RAD21 | RAD21 homolog (S. pombe) | -0.019892 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0195641 |
| SEPTIN2 | septin 2 | -0.0193378 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.018892 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0187655 |
| S100A9 | S100 calcium binding protein A9 | -0.0187132 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0184878 |
| FTL | ferritin, light polypeptide | -0.0183915 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0182861 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) | -0.0182753 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0182322 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0178101 |
| FOXK2 | forkhead box K2 | -0.0175568 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0174243 |
| RPLP0 | ribosomal protein, large, P0 | -0.0174179 |
| GDF15 | growth differentiation factor 15 | -0.017389 |
| PFN1 | profilin 1 | -0.0171102 |
| ZNF292 | zinc finger protein 292 | -0.0169184 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0168355 |
| RTN4 | reticulon 4 | -0.0168031 |
| RPS6 | ribosomal protein S6 | -0.0166286 |
| RPS13 | ribosomal protein S13 | -0.0165232 |
| CDC27 | cell division cycle 27 | -0.0165172 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0164524 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0161864 |
| FAM162A | family with sequence similarity 162, member A | -0.0159867 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0159485 |
| RPL32 | ribosomal protein L32 | -0.0159143 |
| GNAS | GNAS complex locus | -0.01591 |
| SEPTIN7 | septin 7 | -0.0158357 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.015812 |
| RBM25 | RNA binding motif protein 25 | -0.0155061 |
| UBB | ubiquitin B | -0.0154886 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0154527 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0153415 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0153321 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0153319 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0151469 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0151058 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0150127 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0149743 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0149436 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0147977 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.014698 |
| RPS19 | ribosomal protein S19 | -0.0146745 |
| TCERG1 | transcription elongation regulator 1 | -0.0146261 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0144328 |
| VDAC1 | voltage-dependent anion channel 1 | -0.014347 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0143001 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0142865 |
| RPS24 | ribosomal protein S24 | -0.0141995 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0141702 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0140622 |
| RRBP1 | ribosome binding protein 1 | -0.0140579 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0139963 |
| RPL31 | ribosomal protein L31 | -0.013854 |
