| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 4EGI-1 perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 4EGI-1_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.224389 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.147947 |
| SMAD3 | SMAD family member 3 | 0.131538 |
| TSC22D1 | TSC22 domain family, member 1 | 0.110098 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.109152 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.108179 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0922978 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0919451 |
| VCL | vinculin | 0.0912103 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0855096 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0845965 |
| MAP7 | microtubule-associated protein 7 | 0.0841073 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0837408 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0802145 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0761976 |
| MYO1E | myosin IE | 0.0725597 |
| VMP1 | vacuole membrane protein 1 | 0.0724074 |
| B2M | beta-2-microglobulin | 0.0711839 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0704978 |
| PHF3 | PHD finger protein 3 | 0.069491 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0660707 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0624528 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0618609 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0613037 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0597243 |
| FNDC3A | fibronectin type III domain containing 3A | 0.057697 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0570982 |
| YAP1 | Yes-associated protein 1 | 0.0538509 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0536579 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0535987 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0534911 |
| BCL2L1 | BCL2-like 1 | 0.0512081 |
| IFNGR1 | interferon gamma receptor 1 | 0.0492488 |
| FAT1 | FAT atypical cadherin 1 | 0.0469223 |
| STK24 | serine/threonine kinase 24 | 0.0467964 |
| ASPH | aspartate beta-hydroxylase | 0.0457888 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0453509 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0452407 |
| COPA | coatomer protein complex, subunit alpha | 0.0448668 |
| TMC5 | transmembrane channel-like 5 | 0.0443385 |
| AHI1 | Abelson helper integration site 1 | 0.0437472 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0437173 |
| PDZD8 | PDZ domain containing 8 | 0.0428861 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0426248 |
| CANX | calnexin | 0.0413503 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.040745 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0390978 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0377115 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0377014 |
| APP | amyloid beta (A4) precursor protein | 0.0375 |
| EREG | epiregulin | 0.0369489 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0368273 |
| TJP1 | tight junction protein 1 | 0.0366232 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0364397 |
| HM13 | histocompatibility (minor) 13 | 0.0360854 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0357246 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0354896 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0349173 |
| GOLGB1 | golgin B1 | 0.034415 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0342939 |
| RUNX1 | runt-related transcription factor 1 | 0.0342485 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0341895 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0335903 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0328991 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0322943 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0321171 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0319427 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0319217 |
| ETV6 | ets variant 6 | 0.0319158 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0302217 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0300255 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0299909 |
| ADAR | adenosine deaminase, RNA-specific | 0.029947 |
| KYNU | kynureninase | 0.0298823 |
| TMEM65 | transmembrane protein 65 | 0.0295606 |
| FHL2 | four and a half LIM domains 2 | 0.0294568 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.029409 |
| FNIP1 | folliculin interacting protein 1 | 0.0293423 |
| UBC | ubiquitin C | 0.0292717 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0291168 |
| DUSP16 | dual specificity phosphatase 16 | 0.0291055 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0289685 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0285464 |
| SIK3 | SIK family kinase 3 | 0.0282898 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0281663 |
| EFNB2 | ephrin-B2 | 0.0281625 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0280792 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0278547 |
| CALR | calreticulin | 0.0274904 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0273091 |
| DIAPH1 | diaphanous-related formin 1 | 0.0270604 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0270521 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0269848 |
| COG6 | component of oligomeric golgi complex 6 | 0.0267657 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0267321 |
| AFAP1L2 | actin filament associated protein 1-like 2 | 0.0263171 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | 0.0260386 |
| TXNRD1 | thioredoxin reductase 1 | 0.0260073 |
| EHBP1 | EH domain binding protein 1 | 0.0259654 |
| ATF6 | activating transcription factor 6 | 0.0255202 |
| Symbol | Name | Standardized Value |
|---|---|---|
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.138461 |
| NPSR1 | neuropeptide S receptor 1 | -0.13818 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.125621 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.124846 |
| RIGI | RNA sensor RIG-I | -0.10783 |
| RNF213 | ring finger protein 213 | -0.0912578 |
| SQSTM1 | sequestosome 1 | -0.0863475 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0814578 |
| XAF1 | XIAP associated factor 1 | -0.0746999 |
| PRKCA | protein kinase C, alpha | -0.0715217 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0708178 |
| SP100 | SP100 nuclear antigen | -0.0705161 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.068898 |
| MX2 | MX dynamin-like GTPase 2 | -0.0653076 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0641405 |
| MX1 | MX dynamin-like GTPase 1 | -0.0631792 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0617285 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0612346 |
| NDRG1 | N-myc downstream regulated 1 | -0.0604695 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0603798 |
| INTS6 | integrator complex subunit 6 | -0.0585443 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0567167 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | -0.0562234 |
| PLSCR2 | phospholipid scramblase 2 | -0.0524585 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0521974 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0516678 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0490466 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0485985 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0483707 |
| SSH2 | slingshot protein phosphatase 2 | -0.0478554 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | -0.0440363 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0427371 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0424936 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0424145 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0421553 |
| PRELID2 | PRELI domain containing 2 | -0.0417676 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0414177 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0392704 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0388621 |
| PTMA | prothymosin, alpha | -0.0383972 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0380374 |
| AHNAK | AHNAK nucleoprotein | -0.0370354 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0356651 |
| APOL1 | apolipoprotein L, 1 | -0.0356036 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0341975 |
| JUN | jun proto-oncogene | -0.0340722 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0338852 |
| LYZ | lysozyme | -0.0333704 |
| B3GALT5 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 | -0.0333567 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0328893 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0326378 |
| FBXO39 | F-box protein 39 | -0.0325204 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0313767 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0313724 |
| DIAPH3 | diaphanous-related formin 3 | -0.0308878 |
| MECOM | MDS1 and EVI1 complex locus | -0.0304422 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.030157 |
| TMSB10 | thymosin beta 10 | -0.0298757 |
| SDCBP2 | syndecan binding protein (syntenin) 2 | -0.029653 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0289992 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.028767 |
| EGR1 | early growth response 1 | -0.0287022 |
| H1-0 | H1.0 linker histone | -0.0283104 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0282343 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0280709 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0274974 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0273336 |
| PERP | PERP, TP53 apoptosis effector | -0.02724 |
| CMIP | c-Maf inducing protein | -0.0269322 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0259224 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0257567 |
| HLA-E | major histocompatibility complex, class I, E | -0.025648 |
| HLA-B | major histocompatibility complex, class I, B | -0.0253015 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0250373 |
| CCDC146 | coiled-coil domain containing 146 | -0.0250024 |
| PMP22 | peripheral myelin protein 22 | -0.0248999 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0245928 |
| OXSR1 | oxidative stress responsive 1 | -0.0244312 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0243778 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.0241249 |
| SH3PXD2A | SH3 and PX domains 2A | -0.0239783 |
| PLSCR1 | phospholipid scramblase 1 | -0.0239513 |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | -0.0235229 |
| TFRC | transferrin receptor | -0.0232487 |
| CTSD | cathepsin D | -0.0232101 |
| TRIM25 | tripartite motif containing 25 | -0.0231977 |
| TXNIP | thioredoxin interacting protein | -0.0231586 |
| LAMA4 | laminin, alpha 4 | -0.0230869 |
| MUC20 | mucin 20, cell surface associated | -0.0227017 |
| ITGA6 | integrin, alpha 6 | -0.0225476 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa | -0.0224115 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0221619 |
| PTGR1 | prostaglandin reductase 1 | -0.0221269 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.022053 |
| ZBTB7C | zinc finger and BTB domain containing 7C | -0.0218664 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0218047 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | -0.021776 |
| RRM2 | ribonucleotide reductase M2 | -0.0217393 |
| ADIPOR2 | adiponectin receptor 2 | -0.0216981 |
| STK39 | serine threonine kinase 39 | -0.0216404 |
