| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 4EGI-1 perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 4EGI-1_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.106543 |
| ASPH | aspartate beta-hydroxylase | 0.106499 |
| LAMC2 | laminin, gamma 2 | 0.10542 |
| ACTG1 | actin gamma 1 | 0.0928904 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0858839 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0798647 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0789897 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0714898 |
| HMGA2 | high mobility group AT-hook 2 | 0.0672574 |
| RAD51B | RAD51 paralog B | 0.0637547 |
| SVIL | supervillin | 0.0637296 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0631383 |
| ATXN1 | ataxin 1 | 0.0612861 |
| PLEC | plectin | 0.0601791 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0586077 |
| AEBP2 | AE binding protein 2 | 0.0561194 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0557077 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0539307 |
| LAMB3 | laminin, beta 3 | 0.0532796 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0524151 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.052358 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0517219 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0514003 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0507452 |
| APP | amyloid beta (A4) precursor protein | 0.0494644 |
| EGFR | epidermal growth factor receptor | 0.0490332 |
| SMAD3 | SMAD family member 3 | 0.0464877 |
| CD44 | CD44 molecule (Indian blood group) | 0.0449039 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0448238 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0446767 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0440791 |
| GOLGB1 | golgin B1 | 0.0433579 |
| KRT7 | keratin 7, type II | 0.0433351 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0431952 |
| AHNAK | AHNAK nucleoprotein | 0.0425018 |
| RPL13A | ribosomal protein L13a | 0.0424469 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.042218 |
| LAMA4 | laminin, alpha 4 | 0.0415382 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.041451 |
| RPS3 | ribosomal protein S3 | 0.0412754 |
| MACROD2 | MACRO domain containing 2 | 0.0411255 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.041121 |
| DSPP | dentin sialophosphoprotein | 0.0406207 |
| RPS2 | ribosomal protein S2 | 0.04048 |
| INTS6 | integrator complex subunit 6 | 0.0402326 |
| MYO1D | myosin ID | 0.0399607 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0398057 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0394326 |
| RACK1 | receptor for activated C kinase 1 | 0.0383374 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0379334 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0378112 |
| SPATA13 | spermatogenesis associated 13 | 0.0377039 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.037681 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0374212 |
| EHBP1 | EH domain binding protein 1 | 0.0372582 |
| RPL5 | ribosomal protein L5 | 0.0371014 |
| RPS8 | ribosomal protein S8 | 0.0366087 |
| TJP1 | tight junction protein 1 | 0.0365609 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0351627 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0350294 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.034923 |
| FLNA | filamin A, alpha | 0.0348784 |
| RPL37A | ribosomal protein L37a | 0.0344676 |
| THSD7A | thrombospondin, type I, domain containing 7A | 0.0344628 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0344189 |
| VCL | vinculin | 0.0342725 |
| SMYD3 | SET and MYND domain containing 3 | 0.0341031 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0339955 |
| DSG2 | desmoglein 2 | 0.0339114 |
| RPL31 | ribosomal protein L31 | 0.033229 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0331752 |
| CCDC138 | coiled-coil domain containing 138 | 0.0331262 |
| SUMF1 | sulfatase modifying factor 1 | 0.0331255 |
| SGMS2 | sphingomyelin synthase 2 | 0.0328952 |
| DOCK1 | dedicator of cytokinesis 1 | 0.032465 |
| SSH2 | slingshot protein phosphatase 2 | 0.0320829 |
| SEPTIN9 | septin 9 | 0.0317867 |
| FNIP1 | folliculin interacting protein 1 | 0.0317756 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0313084 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | 0.0311272 |
| RPS12 | ribosomal protein S12 | 0.030812 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0306811 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0306232 |
| MYOF | myoferlin | 0.0305808 |
| ENO1 | enolase 1, (alpha) | 0.0302341 |
| KRT86 | keratin 86, type II | 0.0300578 |
| FHIT | fragile histidine triad | 0.0300001 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0298979 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.02989 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0294927 |
| ANXA1 | annexin A1 | 0.0294052 |
| KRT18 | keratin 18, type I | 0.029309 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.029019 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0289708 |
| SET | SET nuclear proto-oncogene | 0.0288487 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0288066 |
| DOCK3 | dedicator of cytokinesis 3 | 0.0283648 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0280512 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0275468 |
| ZRANB3 | zinc finger, RAN-binding domain containing 3 | 0.0274656 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.108157 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0974337 |
| FTL | ferritin, light polypeptide | -0.0927701 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.084974 |
| ZNF292 | zinc finger protein 292 | -0.0809945 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0715678 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0698846 |
| RNF145 | ring finger protein 145 | -0.0682158 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0680316 |
| GOLGA4 | golgin A4 | -0.0564457 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0554408 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0545433 |
| HELZ | helicase with zinc finger | -0.0539172 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0534579 |
| SETD5 | SET domain containing 5 | -0.0531693 |
| WDR45B | WD repeat domain 45B | -0.0495631 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0494041 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0490552 |
| POTEF | POTE ankyrin domain family, member F | -0.0486633 |
| PGK1 | phosphoglycerate kinase 1 | -0.0483543 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0467097 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0463208 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0459592 |
| PTMA | prothymosin, alpha | -0.0455517 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0450463 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0449442 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0448134 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0436319 |
| NUP58 | nucleoporin 58 | -0.043308 |
| RTN4 | reticulon 4 | -0.0430519 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0420347 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0418131 |
| INSIG2 | insulin induced gene 2 | -0.0417894 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0417391 |
| RLF | rearranged L-myc fusion | -0.0416525 |
| MT2A | metallothionein 2A | -0.0412237 |
| TUBA1B | tubulin, alpha 1b | -0.0405278 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0391771 |
| MATR3 | matrin 3 | -0.0375148 |
| FOSL1 | FOS-like antigen 1 | -0.0375002 |
| NKTR | natural killer cell triggering receptor | -0.0373376 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0366603 |
| HMGA1 | high mobility group AT-hook 1 | -0.0366274 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0362628 |
| MT1X | metallothionein 1X | -0.0358915 |
| ANLN | anillin, actin binding protein | -0.0358526 |
| GAS2L3 | growth arrest-specific 2 like 3 | -0.0354096 |
| SEPTIN7 | septin 7 | -0.0353513 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0349201 |
| FAM162A | family with sequence similarity 162, member A | -0.0348114 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0348029 |
| PLS3 | plastin 3 | -0.0347267 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0344377 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0344349 |
| TFG | TRK-fused gene | -0.0342144 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0341817 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0338746 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.033804 |
| TMSB10 | thymosin beta 10 | -0.033314 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0333129 |
| TPD52 | tumor protein D52 | -0.0328933 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0325203 |
| OGA | O-GlcNAcase | -0.0322043 |
| SFXN1 | sideroflexin 1 | -0.0321549 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0320264 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0320069 |
| CBX3 | chromobox homolog 3 | -0.0319592 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | -0.031644 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0313433 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0312731 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0312011 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0309547 |
| RBM39 | RNA binding motif protein 39 | -0.0309106 |
| PHIP | pleckstrin homology domain interacting protein | -0.0309095 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0306792 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0306254 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0305513 |
| PCBP2 | poly(rC) binding protein 2 | -0.0304582 |
| YBX1 | Y box binding protein 1 | -0.0303763 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0301054 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0300208 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0299869 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | -0.0299742 |
| PERP | PERP, TP53 apoptosis effector | -0.0296698 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.029603 |
| S100A6 | S100 calcium binding protein A6 | -0.0293014 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0291903 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.0287236 |
| FLNB | filamin B, beta | -0.02866 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0285881 |
| PFN1 | profilin 1 | -0.028233 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | -0.0280652 |
| AZIN1 | antizyme inhibitor 1 | -0.0279772 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0278638 |
| GNAS | GNAS complex locus | -0.0277587 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0277367 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0277185 |
| MTF2 | metal response element binding transcription factor 2 | -0.0275337 |
| SNX9 | sorting nexin 9 | -0.0274988 |
| XPO1 | exportin 1 | -0.0274273 |
