| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 4EGI-1 perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 4EGI-1_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD44 | CD44 molecule (Indian blood group) | 0.134214 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0955531 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0742734 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0686979 |
| HMGA2 | high mobility group AT-hook 2 | 0.0671835 |
| NAV2 | neuron navigator 2 | 0.0659361 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0603753 |
| VEGFA | vascular endothelial growth factor A | 0.0549515 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0518378 |
| MT2A | metallothionein 2A | 0.0496575 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0437703 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0433677 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0427996 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0416214 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0415177 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.039233 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0387601 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0335968 |
| SQSTM1 | sequestosome 1 | 0.0332922 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0298584 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0294989 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0294314 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.029062 |
| RPS12 | ribosomal protein S12 | 0.0287326 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0285539 |
| PLEC | plectin | 0.0285322 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0282559 |
| CAPRIN2 | caprin family member 2 | 0.0282017 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.027627 |
| RPS8 | ribosomal protein S8 | 0.0276081 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0264048 |
| WWOX | WW domain containing oxidoreductase | 0.0259513 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.025193 |
| RPL12 | ribosomal protein L12 | 0.0249795 |
| CDCP1 | CUB domain containing protein 1 | 0.0244838 |
| SMAD3 | SMAD family member 3 | 0.023927 |
| RND3 | Rho family GTPase 3 | 0.0238306 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0236523 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0235598 |
| RPS2 | ribosomal protein S2 | 0.0233902 |
| MT1E | metallothionein 1E | 0.0229921 |
| PODXL | podocalyxin-like | 0.0229466 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.022597 |
| MLPH | melanophilin | 0.0223127 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0220061 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0219458 |
| TGFB1 | transforming growth factor, beta 1 | 0.021632 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0212238 |
| B2M | beta-2-microglobulin | 0.0210486 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0208665 |
| ANKRD28 | ankyrin repeat domain 28 | 0.02071 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0201642 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0200203 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0197963 |
| RACK1 | receptor for activated C kinase 1 | 0.0196866 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0196317 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0195789 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0190727 |
| FHIT | fragile histidine triad | 0.0188414 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0188282 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0186643 |
| EMP1 | epithelial membrane protein 1 | 0.0185715 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0180572 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0179378 |
| GPC5 | glypican 5 | 0.0178945 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0178023 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0177492 |
| GLRX | glutaredoxin (thioltransferase) | 0.0177041 |
| FNIP1 | folliculin interacting protein 1 | 0.0176216 |
| RPL3 | ribosomal protein L3 | 0.0174761 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0174413 |
| GPC6 | glypican 6 | 0.017381 |
| IL11 | interleukin 11 | 0.0173573 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0173283 |
| TNS1 | tensin 1 | 0.0172775 |
| RPS6 | ribosomal protein S6 | 0.0169765 |
| RPS3 | ribosomal protein S3 | 0.0169302 |
| RPL23 | ribosomal protein L23 | 0.0167083 |
| APP | amyloid beta (A4) precursor protein | 0.0165325 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0164912 |
| SVIL | supervillin | 0.0164017 |
| RPL5 | ribosomal protein L5 | 0.0163323 |
| NRP1 | neuropilin 1 | 0.0163155 |
| PCBP2 | poly(rC) binding protein 2 | 0.0160367 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0158947 |
| JAG1 | jagged 1 | 0.0158738 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0158303 |
| RPS17 | ribosomal protein S17 | 0.0155162 |
| SFTPA2 | surfactant protein A2 | 0.0154954 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.014753 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0142729 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0142447 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0141714 |
| IDS | iduronate 2-sulfatase | 0.0140917 |
| RPL37 | ribosomal protein L37 | 0.0140547 |
| HMGA1 | high mobility group AT-hook 1 | 0.0139565 |
| CTSB | cathepsin B | 0.0138763 |
| ZNF638 | zinc finger protein 638 | 0.0137874 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0136632 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0133193 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.384008 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.212586 |
| VIM | vimentin | -0.176768 |
| TMSB10 | thymosin beta 10 | -0.166486 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.119662 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.117056 |
| PTMA | prothymosin, alpha | -0.108277 |
| COL5A1 | collagen, type V, alpha 1 | -0.103914 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.103759 |
| IGF2 | insulin-like growth factor 2 | -0.0986158 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0954727 |
| CDH13 | cadherin 13 | -0.0890763 |
| TENM2 | teneurin transmembrane protein 2 | -0.0821609 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0815329 |
| PGK1 | phosphoglycerate kinase 1 | -0.0790438 |
| RRBP1 | ribosome binding protein 1 | -0.0749405 |
| LOX | lysyl oxidase | -0.0701385 |
| COL1A1 | collagen, type I, alpha 1 | -0.0684916 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0682312 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0674262 |
| ASPH | aspartate beta-hydroxylase | -0.0650551 |
| FMN1 | formin 1 | -0.060184 |
| CCND1 | cyclin D1 | -0.0596914 |
| CANX | calnexin | -0.0581154 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0576937 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0571346 |
| CALU | calumenin | -0.0557426 |
| LAMB3 | laminin, beta 3 | -0.0554988 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0551862 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0534895 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0525112 |
| GLIS3 | GLIS family zinc finger 3 | -0.0516249 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0507216 |
| NGLY1 | N-glycanase 1 | -0.0474191 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0469168 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0460774 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0457815 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0435187 |
| CAVIN1 | caveolae associated protein 1 | -0.0432578 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0408236 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0406453 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0396871 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0396204 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0389377 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.038694 |
| PDE10A | phosphodiesterase 10A | -0.0383739 |
| ANXA2 | annexin A2 | -0.0382958 |
| FLNB | filamin B, beta | -0.0370671 |
| RAI14 | retinoic acid induced 14 | -0.0367923 |
| TNNC1 | troponin C type 1 (slow) | -0.0364373 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0349868 |
| RTN4 | reticulon 4 | -0.0346328 |
| COL6A1 | collagen, type VI, alpha 1 | -0.03408 |
| AHNAK | AHNAK nucleoprotein | -0.0339211 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0338739 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0337599 |
| GNAS | GNAS complex locus | -0.0337138 |
| NF1 | neurofibromin 1 | -0.0332404 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0328638 |
| SETD5 | SET domain containing 5 | -0.0325251 |
| CLMP | CXADR-like membrane protein | -0.032347 |
| FAM13A | family with sequence similarity 13, member A | -0.0319638 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0319548 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0317595 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0314797 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0314064 |
| HDLBP | high density lipoprotein binding protein | -0.0313021 |
| TMEM263 | transmembrane protein 263 | -0.031166 |
| DIAPH2 | diaphanous-related formin 2 | -0.0309777 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0308784 |
| MYO10 | myosin X | -0.0308622 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0307764 |
| MAP4 | microtubule-associated protein 4 | -0.0306377 |
| SBF2 | SET binding factor 2 | -0.0295762 |
| COL6A3 | collagen, type VI, alpha 3 | -0.029201 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0291824 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0291462 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0288977 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0288691 |
| TPM4 | tropomyosin 4 | -0.0287492 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0284175 |
| DST | dystonin | -0.0279707 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0276484 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0274743 |
| SPAG9 | sperm associated antigen 9 | -0.0274348 |
| GLG1 | golgi glycoprotein 1 | -0.0273225 |
| FSTL1 | follistatin-like 1 | -0.0270889 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0270468 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0267326 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0265554 |
| COL6A2 | collagen, type VI, alpha 2 | -0.026383 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0260372 |
| SEC24D | SEC24 family member D | -0.0255773 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0255089 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0252415 |
| ABLIM3 | actin binding LIM protein family, member 3 | -0.025113 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0250367 |
| CALD1 | caldesmon 1 | -0.0248511 |
| PCBP3 | poly(rC) binding protein 3 | -0.0246728 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0246464 |
