| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 4EGI-1 perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 4EGI-1_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.231089 |
| EXT1 | exostosin glycosyltransferase 1 | 0.201318 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.154132 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.120648 |
| TJP1 | tight junction protein 1 | 0.11698 |
| SMAD3 | SMAD family member 3 | 0.113146 |
| KRT8 | keratin 8, type II | 0.108601 |
| KRT18 | keratin 18, type I | 0.102894 |
| KRT20 | keratin 20, type I | 0.101989 |
| MYO1E | myosin IE | 0.100783 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0985733 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0961601 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0855752 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0803694 |
| EXPH5 | exophilin 5 | 0.0743933 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0743851 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0708138 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0692853 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0687508 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0634802 |
| PLK2 | polo-like kinase 2 | 0.0624049 |
| LYZ | lysozyme | 0.0615353 |
| POF1B | premature ovarian failure, 1B | 0.0610323 |
| AFF1 | AF4/FMR2 family, member 1 | 0.059904 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0582622 |
| ATXN1 | ataxin 1 | 0.0581578 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0562011 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0555472 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0533493 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0533475 |
| CTBP2 | C-terminal binding protein 2 | 0.0505754 |
| SGMS2 | sphingomyelin synthase 2 | 0.0489958 |
| PDZD8 | PDZ domain containing 8 | 0.0485497 |
| SIK3 | SIK family kinase 3 | 0.0476052 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0462427 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0458839 |
| BCL2L1 | BCL2-like 1 | 0.0458612 |
| FOXP1 | forkhead box P1 | 0.044732 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0443725 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0428956 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0426436 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0425802 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0424497 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0421382 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0420766 |
| FAT1 | FAT atypical cadherin 1 | 0.041776 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0410888 |
| ETV6 | ets variant 6 | 0.039806 |
| RPS12 | ribosomal protein S12 | 0.0396701 |
| EMP1 | epithelial membrane protein 1 | 0.0392839 |
| UTRN | utrophin | 0.0392284 |
| INTS6 | integrator complex subunit 6 | 0.0389304 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0385716 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0383743 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0380718 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0380503 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0372402 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0363243 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0361259 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0358673 |
| ASTN2 | astrotactin 2 | 0.0358106 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0356908 |
| FOXO1 | forkhead box O1 | 0.0355763 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0348744 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.034641 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0346224 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0344974 |
| TLE4 | transducin-like enhancer of split 4 | 0.0344225 |
| MYADM | myeloid-associated differentiation marker | 0.0344119 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0341051 |
| MYO5B | myosin VB | 0.0338729 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0338048 |
| VMP1 | vacuole membrane protein 1 | 0.0338048 |
| FHL2 | four and a half LIM domains 2 | 0.0334697 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0333522 |
| TRIB1 | tribbles pseudokinase 1 | 0.0330453 |
| EGFR | epidermal growth factor receptor | 0.0330098 |
| CCNYL1 | cyclin Y-like 1 | 0.0326222 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0326128 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0325138 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0324235 |
| PRR5L | proline rich 5 like | 0.0318063 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.031635 |
| LIMA1 | LIM domain and actin binding 1 | 0.031489 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0314404 |
| RPS16 | ribosomal protein S16 | 0.0311663 |
| NEBL | nebulette | 0.0311598 |
| PGCKA1 | PDCD10 and GCKIII kinases associated 1 | 0.0310633 |
| TMC5 | transmembrane channel-like 5 | 0.0308748 |
| RPS2 | ribosomal protein S2 | 0.030705 |
| RPS3 | ribosomal protein S3 | 0.030555 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0302638 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0302324 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0299867 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0299255 |
| GOLGB1 | golgin B1 | 0.0298834 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0295905 |
| LAMA4 | laminin, alpha 4 | 0.0294877 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0293733 |
| DST | dystonin | 0.0292857 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.136273 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0798049 |
| PTMA | prothymosin, alpha | -0.068454 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.065027 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0590463 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0556626 |
| OGA | O-GlcNAcase | -0.0552127 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0549971 |
| RBM39 | RNA binding motif protein 39 | -0.053162 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0509348 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0505988 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0468605 |
| ZNF292 | zinc finger protein 292 | -0.0459558 |
| VIM | vimentin | -0.0442369 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0434951 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0430909 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0429965 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0407008 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0399608 |
| TMSB10 | thymosin beta 10 | -0.0379094 |
| THOC2 | THO complex 2 | -0.0377561 |
| RTN4 | reticulon 4 | -0.0374369 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0367612 |
| GOLGA4 | golgin A4 | -0.0340209 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0336739 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0335642 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0331718 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.030837 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0303286 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0298953 |
| PTK2 | protein tyrosine kinase 2 | -0.0295174 |
| SBF2 | SET binding factor 2 | -0.0290367 |
| TMEM41B | transmembrane protein 41B | -0.0288793 |
| TXNRD1 | thioredoxin reductase 1 | -0.0287583 |
| PGK1 | phosphoglycerate kinase 1 | -0.0286903 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0285945 |
| ANLN | anillin, actin binding protein | -0.0284768 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0281819 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0280787 |
| USP3 | ubiquitin specific peptidase 3 | -0.0276287 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0272308 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0271381 |
| FAM13A | family with sequence similarity 13, member A | -0.0267365 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0261607 |
| CENPF | centromere protein F, 350/400kDa | -0.026072 |
| HELZ | helicase with zinc finger | -0.0260492 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0255816 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0252302 |
| RLF | rearranged L-myc fusion | -0.0248077 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0247667 |
| TPD52 | tumor protein D52 | -0.0235805 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0234631 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0233384 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0233357 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0231926 |
| EZR | ezrin | -0.0231479 |
| H1-0 | H1.0 linker histone | -0.0230356 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0229355 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0228029 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.0226723 |
| POMP | proteasome maturation protein | -0.0225517 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0221907 |
| PTEN | phosphatase and tensin homolog | -0.0220987 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0220742 |
| CCNL1 | cyclin L1 | -0.0220296 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.022007 |
| RNF145 | ring finger protein 145 | -0.0218046 |
| FOSL1 | FOS-like antigen 1 | -0.0217494 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.021619 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.0215157 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0215023 |
| DENND4C | DENN/MADD domain containing 4C | -0.0213982 |
| GNAS | GNAS complex locus | -0.0213616 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0212711 |
| FAM162A | family with sequence similarity 162, member A | -0.0212031 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | -0.0211252 |
| PDS5B | PDS5 cohesin associated factor B | -0.020855 |
| SETD5 | SET domain containing 5 | -0.0207984 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.020696 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0205304 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.020505 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0203535 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0201889 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0201835 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0201808 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0201135 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0201 |
| RSBN1L | round spermatid basic protein 1-like | -0.0200584 |
| WASF2 | WAS protein family, member 2 | -0.0199963 |
| NIBAN2 | niban apoptosis regulator 2 | -0.0198859 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0198347 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0196049 |
| CTTNBP2NL | CTTNBP2 N-terminal like | -0.0195513 |
| MATR3 | matrin 3 | -0.0194895 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0193817 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0192907 |
| ATP11B | ATPase, class VI, type 11B | -0.0192722 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.0192233 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.019149 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0191305 |
