| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 4EGI-1 perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 4EGI-1_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RAI14 | retinoic acid induced 14 | 0.0831846 |
| MYOF | myoferlin | 0.058354 |
| PDLIM5 | PDZ and LIM domain 5 | 0.055595 |
| LMO7 | LIM domain 7 | 0.052855 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0466198 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0463363 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0445475 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0390072 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.03776 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.037239 |
| NAV2 | neuron navigator 2 | 0.0371821 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0365445 |
| SMAD3 | SMAD family member 3 | 0.0350201 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0349777 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0341119 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0339381 |
| OSBPL6 | oxysterol binding protein-like 6 | 0.0334108 |
| MTSS1 | metastasis suppressor 1 | 0.0316327 |
| CNTNAP3 | contactin associated protein-like 3 | 0.0283457 |
| AOPEP | aminopeptidase O (putative) | 0.0261424 |
| PRSS23 | protease, serine, 23 | 0.0256965 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0255222 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0244548 |
| HMGA2 | high mobility group AT-hook 2 | 0.0234758 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0233729 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0232399 |
| OSMR | oncostatin M receptor | 0.0227419 |
| AHNAK | AHNAK nucleoprotein | 0.0226955 |
| PLEC | plectin | 0.0226108 |
| PTK2 | protein tyrosine kinase 2 | 0.0225259 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.0222054 |
| LAMC2 | laminin, gamma 2 | 0.0212592 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0210844 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0210164 |
| PLS3 | plastin 3 | 0.0205925 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0204285 |
| BARX2 | BARX homeobox 2 | 0.0204264 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0196187 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.019506 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0193286 |
| CLIC4 | chloride intracellular channel 4 | 0.018024 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0179478 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.0178095 |
| SVIL | supervillin | 0.0176354 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0173833 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0172681 |
| DOK5 | docking protein 5 | 0.0171783 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.017151 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0171154 |
| RNF217 | ring finger protein 217 | 0.0169778 |
| UTRN | utrophin | 0.0165069 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0164459 |
| EFCAB13 | EF-hand calcium binding domain 13 | 0.0161114 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0160461 |
| CUL4B | cullin 4B | 0.0156443 |
| TMEM65 | transmembrane protein 65 | 0.0151477 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0145694 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0144445 |
| CDHR3 | cadherin-related family member 3 | 0.0144129 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0142082 |
| KAT6A | K(lysine) acetyltransferase 6A | 0.0140525 |
| FOXP1 | forkhead box P1 | 0.0138891 |
| MED13L | mediator complex subunit 13-like | 0.013669 |
| DUSP4 | dual specificity phosphatase 4 | 0.0134824 |
| LYST | lysosomal trafficking regulator | 0.0134818 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0134724 |
| VCL | vinculin | 0.0134476 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0134388 |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 | 0.0134085 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0133021 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.013288 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0131605 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0129605 |
| SETBP1 | SET binding protein 1 | 0.0126842 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 0.0126296 |
| ANO6 | anoctamin 6 | 0.0125704 |
| IL6ST | interleukin 6 signal transducer | 0.0124727 |
| FRMD6 | FERM domain containing 6 | 0.0124037 |
| ASPH | aspartate beta-hydroxylase | 0.0121576 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0120956 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0120441 |
| EFNA5 | ephrin-A5 | 0.0120352 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0119638 |
| JAG1 | jagged 1 | 0.011795 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0116492 |
| ADAMTS17 | ADAM metallopeptidase with thrombospondin type 1 motif, 17 | 0.0115435 |
| MTAP | methylthioadenosine phosphorylase | 0.0114444 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0114174 |
| RALGAPB | Ral GTPase activating protein, beta subunit (non-catalytic) | 0.0113053 |
| FMNL2 | formin-like 2 | 0.0112676 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0112398 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0112355 |
| CAPRIN2 | caprin family member 2 | 0.0111667 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0111626 |
| APP | amyloid beta (A4) precursor protein | 0.0109401 |
| FAM3C | family with sequence similarity 3, member C | 0.0107626 |
| PRELID2 | PRELI domain containing 2 | 0.0107189 |
| KIAA1217 | KIAA1217 | 0.0106531 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0106126 |
| NOTCH2 | notch 2 | 0.0106003 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.14853 |
| FLNB | filamin B, beta | -0.147899 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.131333 |
| PTMA | prothymosin, alpha | -0.104437 |
| NDRG1 | N-myc downstream regulated 1 | -0.101559 |
| B2M | beta-2-microglobulin | -0.0788834 |
| TMSB10 | thymosin beta 10 | -0.0779572 |
| MT2A | metallothionein 2A | -0.0742882 |
| POTEF | POTE ankyrin domain family, member F | -0.0700301 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0692814 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0663584 |
| RPS21 | ribosomal protein S21 | -0.0657719 |
| S100A10 | S100 calcium binding protein A10 | -0.0638657 |
| HLA-B | major histocompatibility complex, class I, B | -0.0597529 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0596443 |
| RPS6 | ribosomal protein S6 | -0.0595159 |
| RPS8 | ribosomal protein S8 | -0.0569352 |
| RPLP2 | ribosomal protein, large, P2 | -0.0547869 |
| LDHA | lactate dehydrogenase A | -0.0496301 |
| PGK1 | phosphoglycerate kinase 1 | -0.0484451 |
| LMNA | lamin A/C | -0.0469454 |
| RPS13 | ribosomal protein S13 | -0.0465493 |
| SULF1 | sulfatase 1 | -0.0454149 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0448269 |
| RPL11 | ribosomal protein L11 | -0.0446806 |
| ITGA6 | integrin, alpha 6 | -0.044483 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0438217 |
| RPLP1 | ribosomal protein, large, P1 | -0.0437339 |
| GNAS | GNAS complex locus | -0.042945 |
| ENO1 | enolase 1, (alpha) | -0.0425359 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0418073 |
| RPL35A | ribosomal protein L35a | -0.0403118 |
| CLU | clusterin | -0.0385495 |
| EMP1 | epithelial membrane protein 1 | -0.0382328 |
| FTL | ferritin, light polypeptide | -0.0376215 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0375972 |
| RPS25 | ribosomal protein S25 | -0.0370651 |
| RPS19 | ribosomal protein S19 | -0.0366992 |
| S100A9 | S100 calcium binding protein A9 | -0.0351147 |
| RPL37A | ribosomal protein L37a | -0.0347482 |
| ANXA2 | annexin A2 | -0.0346684 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.034399 |
| IGF2 | insulin-like growth factor 2 | -0.0343113 |
| RPS24 | ribosomal protein S24 | -0.0338364 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0332158 |
| PKM | pyruvate kinase, muscle | -0.0329262 |
| RPL8 | ribosomal protein L8 | -0.0328657 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0321422 |
| RPL31 | ribosomal protein L31 | -0.0318303 |
| S100A11 | S100 calcium binding protein A11 | -0.0318092 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.031678 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0314964 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0311678 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0311544 |
| RPS3 | ribosomal protein S3 | -0.0310599 |
| EZR | ezrin | -0.0310575 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0308803 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0303826 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0303542 |
| TMSB4X | thymosin beta 4, X-linked | -0.0302184 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0301649 |
| S100A6 | S100 calcium binding protein A6 | -0.0301246 |
| HM13 | histocompatibility (minor) 13 | -0.0295928 |
| RPL34 | ribosomal protein L34 | -0.0293756 |
| CALU | calumenin | -0.0293255 |
| RPL37 | ribosomal protein L37 | -0.0288656 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0287632 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.028551 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0283165 |
| RPL23 | ribosomal protein L23 | -0.0280931 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0279681 |
| S100A2 | S100 calcium binding protein A2 | -0.0279575 |
| RPS27A | ribosomal protein S27a | -0.0278314 |
| RPS12 | ribosomal protein S12 | -0.0276974 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0271454 |
| SQLE | squalene epoxidase | -0.0270493 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0265252 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0261469 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | -0.0260453 |
| RPS23 | ribosomal protein S23 | -0.0259687 |
| RPS14 | ribosomal protein S14 | -0.0257047 |
| RPL12 | ribosomal protein L12 | -0.025193 |
| RPS27 | ribosomal protein S27 | -0.0251518 |
| MKI67 | marker of proliferation Ki-67 | -0.0251217 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0250715 |
| RPS29 | ribosomal protein S29 | -0.0247102 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0246389 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0245748 |
| GOLGA4 | golgin A4 | -0.0243735 |
| RPL19 | ribosomal protein L19 | -0.0243523 |
| RPL36 | ribosomal protein L36 | -0.0238914 |
| WASF2 | WAS protein family, member 2 | -0.0238872 |
| RPL36A | ribosomal protein L36a | -0.0238239 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0236125 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0235538 |
| HLA-A | major histocompatibility complex, class I, A | -0.0235144 |
| TAGLN2 | transgelin 2 | -0.0233944 |
| RPL26 | ribosomal protein L26 | -0.0233849 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0233465 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0232191 |
