| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 4EGI-1 perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 4EGI-1_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.116268 |
| B2M | beta-2-microglobulin | 0.0950232 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0756553 |
| POTEF | POTE ankyrin domain family, member F | 0.0755722 |
| MT2A | metallothionein 2A | 0.0725318 |
| KRT8 | keratin 8, type II | 0.0720555 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0683816 |
| ERBIN | erbb2 interacting protein | 0.0651952 |
| CD44 | CD44 molecule (Indian blood group) | 0.0635585 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0631028 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.0603916 |
| PTK2 | protein tyrosine kinase 2 | 0.0570835 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0522755 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0493322 |
| MT1X | metallothionein 1X | 0.0490539 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0482783 |
| TPM3 | tropomyosin 3 | 0.0473706 |
| MSN | moesin | 0.0469954 |
| FOSL1 | FOS-like antigen 1 | 0.0467301 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0455308 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0454235 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0447981 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0405536 |
| ATP13A3 | ATPase type 13A3 | 0.0397769 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0391918 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0378824 |
| SMAD3 | SMAD family member 3 | 0.0364045 |
| KRT7 | keratin 7, type II | 0.036124 |
| ANXA5 | annexin A5 | 0.0360338 |
| NAV2 | neuron navigator 2 | 0.0357875 |
| PCBP2 | poly(rC) binding protein 2 | 0.034429 |
| ANKRD33B | ankyrin repeat domain 33B | 0.034285 |
| SET | SET nuclear proto-oncogene | 0.034237 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.03396 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0332681 |
| AXL | AXL receptor tyrosine kinase | 0.0327668 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0310205 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0309689 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0307351 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0306791 |
| NUP153 | nucleoporin 153kDa | 0.0303085 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0299489 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0299383 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0282563 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.0282244 |
| KRT18 | keratin 18, type I | 0.0279895 |
| ZNF148 | zinc finger protein 148 | 0.0279876 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0271624 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0270765 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0261839 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0259353 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.025627 |
| TPM1 | tropomyosin 1 (alpha) | 0.0250281 |
| STK24 | serine/threonine kinase 24 | 0.0245408 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.0245007 |
| UBQLN1 | ubiquilin 1 | 0.0238008 |
| ANO6 | anoctamin 6 | 0.0232564 |
| TXNRD1 | thioredoxin reductase 1 | 0.0230818 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.0229499 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0227885 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.022063 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0220188 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0218389 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0217966 |
| NEK7 | NIMA-related kinase 7 | 0.0216257 |
| VEGFA | vascular endothelial growth factor A | 0.021497 |
| CCNL1 | cyclin L1 | 0.0208728 |
| NUP58 | nucleoporin 58 | 0.0206559 |
| JMJD1C | jumonji domain containing 1C | 0.020645 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0205558 |
| NCKAP1 | NCK-associated protein 1 | 0.0202406 |
| PLSCR1 | phospholipid scramblase 1 | 0.0202017 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0201819 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0200931 |
| VEGFC | vascular endothelial growth factor C | 0.0199616 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.0199151 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0198324 |
| UBC | ubiquitin C | 0.0197277 |
| DIAPH1 | diaphanous-related formin 1 | 0.0196884 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0196786 |
| TPD52 | tumor protein D52 | 0.0195923 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0193467 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0191198 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | 0.0190992 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0190275 |
| RASA2 | RAS p21 protein activator 2 | 0.0189113 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0185692 |
| CALD1 | caldesmon 1 | 0.0184221 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0182349 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.018173 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0181066 |
| VMP1 | vacuole membrane protein 1 | 0.0180778 |
| ANXA1 | annexin A1 | 0.0180204 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0179637 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0179492 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0179435 |
| LMO7 | LIM domain 7 | 0.0176416 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.017622 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0175823 |
| BCL2L1 | BCL2-like 1 | 0.0175034 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.271381 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.266762 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.15362 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.150176 |
| HLA-B | major histocompatibility complex, class I, B | -0.1303 |
| FTL | ferritin, light polypeptide | -0.124238 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.116031 |
| NDRG1 | N-myc downstream regulated 1 | -0.107133 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0993818 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0988264 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0915401 |
| AHNAK | AHNAK nucleoprotein | -0.0857867 |
| CANX | calnexin | -0.076385 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0747698 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0697837 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0618587 |
| CAVIN1 | caveolae associated protein 1 | -0.0605634 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0578598 |
| PGK1 | phosphoglycerate kinase 1 | -0.0572419 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.056523 |
| PTMA | prothymosin, alpha | -0.0527956 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0520407 |
| VIM | vimentin | -0.0516619 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0491753 |
| PLIN2 | perilipin 2 | -0.0447023 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0433193 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0430647 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0428483 |
| INTS6 | integrator complex subunit 6 | -0.0423056 |
| SQSTM1 | sequestosome 1 | -0.0418519 |
| ZNF804A | zinc finger protein 804A | -0.0413034 |
| LOX | lysyl oxidase | -0.0406416 |
| GNAS | GNAS complex locus | -0.0380434 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0379168 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0366026 |
| TMSB10 | thymosin beta 10 | -0.0360815 |
| RPL35A | ribosomal protein L35a | -0.0360391 |
| CTSD | cathepsin D | -0.0359334 |
| STK4 | serine/threonine kinase 4 | -0.0357074 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0342427 |
| RPLP2 | ribosomal protein, large, P2 | -0.0342033 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0340973 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0336831 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0335272 |
| ANXA2 | annexin A2 | -0.0330785 |
| HLA-A | major histocompatibility complex, class I, A | -0.032742 |
| RND3 | Rho family GTPase 3 | -0.0325929 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.032554 |
| GLIS3 | GLIS family zinc finger 3 | -0.031933 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0318751 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.0311771 |
| DTNA | dystrobrevin, alpha | -0.031118 |
| HLA-E | major histocompatibility complex, class I, E | -0.0307702 |
| RPS8 | ribosomal protein S8 | -0.0297999 |
| RAI14 | retinoic acid induced 14 | -0.0297955 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0293302 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0285421 |
| ZNF432 | zinc finger protein 432 | -0.0280238 |
| IER3 | immediate early response 3 | -0.0278123 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0275976 |
| RPS24 | ribosomal protein S24 | -0.0274985 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0269588 |
| RPL26 | ribosomal protein L26 | -0.0269023 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0268796 |
| ASPH | aspartate beta-hydroxylase | -0.0267177 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0264732 |
| RPS27A | ribosomal protein S27a | -0.0264286 |
| TUBB | tubulin, beta class I | -0.025943 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0257336 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.025551 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0248976 |
| ZXDC | ZXD family zinc finger C | -0.0245449 |
| RTN3 | reticulon 3 | -0.0245348 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0243866 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0243204 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0240847 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0240821 |
| HLA-C | major histocompatibility complex, class I, C | -0.0236533 |
| FSTL1 | follistatin-like 1 | -0.0232479 |
| RRBP1 | ribosome binding protein 1 | -0.0227982 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0225737 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0225619 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0224834 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0223549 |
| CCBE1 | collagen and calcium binding EGF domains 1 | -0.0222328 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0222298 |
| DIPK2A | divergent protein kinase domain 2A | -0.022029 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0220042 |
| CD63 | CD63 molecule | -0.0219168 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0216723 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0215042 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0213847 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0210055 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0209879 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0207682 |
| ADM | adrenomedullin | -0.0207533 |
| LOXL2 | lysyl oxidase-like 2 | -0.0206873 |
| RPL12 | ribosomal protein L12 | -0.020669 |
| RPS6 | ribosomal protein S6 | -0.0205857 |
| AEBP2 | AE binding protein 2 | -0.0204316 |
