| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 4EGI-1 perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 4EGI-1_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.198807 |
| EXT1 | exostosin glycosyltransferase 1 | 0.142806 |
| HMGA2 | high mobility group AT-hook 2 | 0.12477 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.11687 |
| HDAC9 | histone deacetylase 9 | 0.107057 |
| ACTG1 | actin gamma 1 | 0.102859 |
| RPS12 | ribosomal protein S12 | 0.0983249 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0911723 |
| RPS2 | ribosomal protein S2 | 0.0842235 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0772101 |
| EFNA5 | ephrin-A5 | 0.073369 |
| DTNA | dystrobrevin, alpha | 0.0730672 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0715979 |
| LSAMP | limbic system-associated membrane protein | 0.0705761 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0694524 |
| FTL | ferritin, light polypeptide | 0.067554 |
| ASPH | aspartate beta-hydroxylase | 0.0632933 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0615762 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0613644 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.060163 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0579932 |
| RPS3 | ribosomal protein S3 | 0.0578187 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0572368 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0546317 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0509426 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.050841 |
| RPL5 | ribosomal protein L5 | 0.0492742 |
| RACK1 | receptor for activated C kinase 1 | 0.0479254 |
| RPS17 | ribosomal protein S17 | 0.0476059 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0464445 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0463184 |
| DOCK4 | dedicator of cytokinesis 4 | 0.045932 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0455229 |
| PRKCE | protein kinase C, epsilon | 0.0453093 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0448084 |
| INTS6 | integrator complex subunit 6 | 0.0445052 |
| RPL37A | ribosomal protein L37a | 0.0406862 |
| USP34 | ubiquitin specific peptidase 34 | 0.040228 |
| ENO1 | enolase 1, (alpha) | 0.0400082 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0392533 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0371234 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0365502 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0362434 |
| BPTF | bromodomain PHD finger transcription factor | 0.0360774 |
| SAMD3 | sterile alpha motif domain containing 3 | 0.0360465 |
| RPS8 | ribosomal protein S8 | 0.0359283 |
| GPHN | gephyrin | 0.0358375 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0357373 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0355624 |
| RPL21 | ribosomal protein L21 | 0.0355183 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0352027 |
| ZNF638 | zinc finger protein 638 | 0.0347912 |
| RUNX1 | runt-related transcription factor 1 | 0.0345367 |
| TPM3 | tropomyosin 3 | 0.0342783 |
| RPL12 | ribosomal protein L12 | 0.034049 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0339606 |
| RPL7 | ribosomal protein L7 | 0.0338462 |
| NAV3 | neuron navigator 3 | 0.0336853 |
| BRD2 | bromodomain containing 2 | 0.0329769 |
| FLNA | filamin A, alpha | 0.0327844 |
| SET | SET nuclear proto-oncogene | 0.0323945 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0319042 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0317227 |
| RPL3 | ribosomal protein L3 | 0.0314401 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0312487 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.031128 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0305641 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0305196 |
| EGR1 | early growth response 1 | 0.0294383 |
| ADAM32 | ADAM metallopeptidase domain 32 | 0.0293861 |
| LIMA1 | LIM domain and actin binding 1 | 0.0293111 |
| DGKI | diacylglycerol kinase, iota | 0.0285204 |
| SFPQ | splicing factor proline/glutamine-rich | 0.028473 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0283243 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0282952 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0281722 |
| RPL23 | ribosomal protein L23 | 0.0281472 |
| MSR1 | macrophage scavenger receptor 1 | 0.0278652 |
| RPL31 | ribosomal protein L31 | 0.0272286 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0270555 |
| PLEC | plectin | 0.026913 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0265351 |
| ARFGEF3 | ARFGEF family member 3 | 0.0264937 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.026386 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0263129 |
| RPS18 | ribosomal protein S18 | 0.0262603 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0258704 |
| AEBP2 | AE binding protein 2 | 0.0255578 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0254857 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0254781 |
| NTM | neurotrimin | 0.025447 |
| PUM3 | pumilio RNA binding family member 3 | 0.0254352 |
| KLHL29 | kelch-like family member 29 | 0.0251191 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0247469 |
| EGFR | epidermal growth factor receptor | 0.0247419 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.024554 |
| RPS6 | ribosomal protein S6 | 0.0243553 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0242533 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0242512 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0240478 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.212186 |
| PTMA | prothymosin, alpha | -0.162266 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.109021 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.100655 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0999089 |
| GPC6 | glypican 6 | -0.0993103 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0983114 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0928959 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0902534 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0831964 |
| RTN4 | reticulon 4 | -0.0748425 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0744398 |
| ZNF292 | zinc finger protein 292 | -0.0722956 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0698906 |
| ANXA2 | annexin A2 | -0.0669925 |
| GNAS | GNAS complex locus | -0.0667182 |
| VIM | vimentin | -0.0658005 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0653976 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0644924 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0642313 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0632394 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0625131 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0621367 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0610702 |
| RBM39 | RNA binding motif protein 39 | -0.0606604 |
| PGK1 | phosphoglycerate kinase 1 | -0.0604654 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0591516 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0591142 |
| AHNAK | AHNAK nucleoprotein | -0.0588983 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.055336 |
| H1-0 | H1.0 linker histone | -0.0537728 |
| CDH13 | cadherin 13 | -0.050646 |
| CD109 | CD109 molecule | -0.0506046 |
| VCL | vinculin | -0.0503663 |
| QKI | QKI, KH domain containing, RNA binding | -0.0482142 |
| TMEM263 | transmembrane protein 263 | -0.0462245 |
| CAVIN1 | caveolae associated protein 1 | -0.0460615 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0453689 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0452738 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0449047 |
| SPAG9 | sperm associated antigen 9 | -0.0437454 |
| RLF | rearranged L-myc fusion | -0.0433903 |
| PTK2 | protein tyrosine kinase 2 | -0.0431811 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0427799 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0410763 |
| FAM162A | family with sequence similarity 162, member A | -0.04092 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.040871 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0404433 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0403676 |
| OGA | O-GlcNAcase | -0.0402346 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0401655 |
| USP3 | ubiquitin specific peptidase 3 | -0.0399395 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0399354 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0395707 |
| SEPTIN7 | septin 7 | -0.039497 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0394685 |
| NUP58 | nucleoporin 58 | -0.0391444 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0380977 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0369777 |
| RPL35A | ribosomal protein L35a | -0.0368126 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0365318 |
| MMP12 | matrix metallopeptidase 12 | -0.0363673 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0362355 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0360875 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0355458 |
| RPS24 | ribosomal protein S24 | -0.0350031 |
| PTCHD4 | patched domain containing 4 | -0.0349286 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.034809 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0343733 |
| KPNB1 | karyopherin (importin) beta 1 | -0.034304 |
| RNF145 | ring finger protein 145 | -0.0330877 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0330315 |
| HELZ | helicase with zinc finger | -0.0329703 |
| IER3 | immediate early response 3 | -0.0325567 |
| NDRG1 | N-myc downstream regulated 1 | -0.0325416 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0323815 |
| ANLN | anillin, actin binding protein | -0.0323363 |
| TPM4 | tropomyosin 4 | -0.0317483 |
| HAS2 | hyaluronan synthase 2 | -0.0316728 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0313366 |
| KLF6 | Kruppel-like factor 6 | -0.0308859 |
| DIAPH3 | diaphanous-related formin 3 | -0.0303488 |
| SETD5 | SET domain containing 5 | -0.0300159 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0288102 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0287216 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0286982 |
| RPL6 | ribosomal protein L6 | -0.0285735 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0285734 |
| ZNF217 | zinc finger protein 217 | -0.0285624 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0281358 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0281321 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0279374 |
| FN1 | fibronectin 1 | -0.0278182 |
| CD2AP | CD2-associated protein | -0.027814 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0276726 |
| TFG | TRK-fused gene | -0.0276714 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0274917 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0273839 |
| LMNA | lamin A/C | -0.0273403 |
| TMEM123 | transmembrane protein 123 | -0.0272791 |
