| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 4EGI-1 perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 4EGI-1_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EXT1 | exostosin glycosyltransferase 1 | 0.0802976 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0548124 |
| MT2A | metallothionein 2A | 0.0535012 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.050127 |
| LMO7 | LIM domain 7 | 0.0488309 |
| MYO1E | myosin IE | 0.0487233 |
| ONECUT3 | one cut homeobox 3 | 0.0466102 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0407499 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0371318 |
| MT1E | metallothionein 1E | 0.0340337 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0313638 |
| POF1B | premature ovarian failure, 1B | 0.0311713 |
| FAT1 | FAT atypical cadherin 1 | 0.0294432 |
| ATXN1 | ataxin 1 | 0.0276339 |
| RPLP1 | ribosomal protein, large, P1 | 0.0267199 |
| RAD51B | RAD51 paralog B | 0.0264771 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0261022 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0260957 |
| NEBL | nebulette | 0.0257651 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0249777 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0249585 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.0245561 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0245422 |
| CADPS2 | Ca++-dependent secretion activator 2 | 0.0244865 |
| ASPH | aspartate beta-hydroxylase | 0.0242592 |
| EGFR | epidermal growth factor receptor | 0.0238502 |
| KRT8 | keratin 8, type II | 0.0233389 |
| SMYD3 | SET and MYND domain containing 3 | 0.0221141 |
| CADPS | Ca++-dependent secretion activator | 0.0220536 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0217658 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0212379 |
| CUX1 | cut-like homeobox 1 | 0.0209187 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0206601 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0206191 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0206087 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.0204947 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0202184 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0202055 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0201598 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0200234 |
| AFF1 | AF4/FMR2 family, member 1 | 0.020019 |
| AEBP2 | AE binding protein 2 | 0.0199385 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0197526 |
| EXOC6B | exocyst complex component 6B | 0.0197253 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0196317 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0195157 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0193527 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0193259 |
| PDZD8 | PDZ domain containing 8 | 0.018727 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0185239 |
| GOLGB1 | golgin B1 | 0.0182083 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0182081 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0181809 |
| PRELID2 | PRELI domain containing 2 | 0.0180937 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.0180473 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0180056 |
| FOXP1 | forkhead box P1 | 0.0179839 |
| RPL34 | ribosomal protein L34 | 0.0179133 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0176176 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0173106 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0172413 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0164982 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0162211 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0161649 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0156314 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0156278 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0156204 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0155262 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0155137 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.015446 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0153161 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0152183 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0150349 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0149843 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.0148729 |
| RPS24 | ribosomal protein S24 | 0.0148586 |
| METTL15 | methyltransferase like 15 | 0.0143221 |
| COMMD10 | COMM domain containing 10 | 0.0139506 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0139307 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.013776 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0137617 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0137133 |
| RIGI | RNA sensor RIG-I | 0.0136703 |
| CRY1 | cryptochrome circadian clock 1 | 0.0135715 |
| RPL38 | ribosomal protein L38 | 0.0135708 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0134571 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0134438 |
| RPL14 | ribosomal protein L14 | 0.0134168 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.0133723 |
| PGM3 | phosphoglucomutase 3 | 0.0133498 |
| ATF6 | activating transcription factor 6 | 0.0132774 |
| PRDX1 | peroxiredoxin 1 | 0.0131361 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 | 0.0131169 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0130384 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0129733 |
| AHI1 | Abelson helper integration site 1 | 0.0129108 |
| TMEM14B | transmembrane protein 14B | 0.0128956 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0128582 |
| TMCO3 | transmembrane and coiled-coil domains 3 | 0.012807 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0128039 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.164048 |
| NDRG1 | N-myc downstream regulated 1 | -0.151798 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.122832 |
| PTMA | prothymosin, alpha | -0.117488 |
| TXNIP | thioredoxin interacting protein | -0.115771 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.105328 |
| ITGA6 | integrin, alpha 6 | -0.0924937 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0894491 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0879878 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0848764 |
| FAM13A | family with sequence similarity 13, member A | -0.08355 |
| TNS4 | tensin 4 | -0.0788459 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0779404 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0772523 |
| ANXA2 | annexin A2 | -0.0756946 |
| FLNB | filamin B, beta | -0.0740977 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0738282 |
| EZR | ezrin | -0.0716675 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0697454 |
| RNF145 | ring finger protein 145 | -0.0684405 |
| NPSR1 | neuropeptide S receptor 1 | -0.068235 |
| GPHN | gephyrin | -0.0666057 |
| MED13L | mediator complex subunit 13-like | -0.063503 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0626152 |
| GOLGA4 | golgin A4 | -0.0609308 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0602981 |
| SETD5 | SET domain containing 5 | -0.0597618 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0596323 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0596242 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0583061 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0565841 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0551058 |
| ZNF292 | zinc finger protein 292 | -0.0527902 |
| MLEC | malectin | -0.0524155 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0519647 |
| CCNY | cyclin Y | -0.0519636 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0507635 |
| HMGA1 | high mobility group AT-hook 1 | -0.0499786 |
| KRT18 | keratin 18, type I | -0.0484806 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0476131 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0469021 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0467277 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0464887 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0464295 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0462344 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0457717 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0451312 |
| CALB1 | calbindin 1, 28kDa | -0.0443996 |
| NUP58 | nucleoporin 58 | -0.0428361 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0421475 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.042027 |
| FNBP1L | formin binding protein 1-like | -0.0420266 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0415512 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0413497 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0409356 |
| INSIG1 | insulin induced gene 1 | -0.040746 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0407355 |
| WDR45B | WD repeat domain 45B | -0.0406882 |
| EPCAM | epithelial cell adhesion molecule | -0.0399926 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0395884 |
| USP3 | ubiquitin specific peptidase 3 | -0.0395456 |
| RREB1 | ras responsive element binding protein 1 | -0.0394018 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0393365 |
| TPM4 | tropomyosin 4 | -0.0382463 |
| FOSL1 | FOS-like antigen 1 | -0.0378853 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0376027 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.037308 |
| ITGB4 | integrin, beta 4 | -0.0370093 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0369507 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0369189 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | -0.0369068 |
| RBM39 | RNA binding motif protein 39 | -0.0362843 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0360614 |
| TFG | TRK-fused gene | -0.0359825 |
| POTEF | POTE ankyrin domain family, member F | -0.0359376 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.035713 |
| PERP | PERP, TP53 apoptosis effector | -0.0355516 |
| KRT19 | keratin 19, type I | -0.0353353 |
| CCNL1 | cyclin L1 | -0.0351841 |
| AREG | amphiregulin | -0.0351795 |
| EXOC1 | exocyst complex component 1 | -0.0351113 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | -0.0347073 |
| MUC17 | mucin 17, cell surface associated | -0.0346027 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0342402 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0339758 |
| ABHD2 | abhydrolase domain containing 2 | -0.0335885 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0328526 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0326404 |
| PIGR | polymeric immunoglobulin receptor | -0.0322931 |
| COPA | coatomer protein complex, subunit alpha | -0.0320585 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.031944 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0318867 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0317271 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0317044 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.0316894 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0314955 |
| RPS6 | ribosomal protein S6 | -0.0314378 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0313917 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.0308603 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0305763 |
