| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 4EGI-1 perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 4EGI-1_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0886378 |
| NAV2 | neuron navigator 2 | 0.0745749 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0741493 |
| SQSTM1 | sequestosome 1 | 0.0614107 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0570272 |
| SMAD3 | SMAD family member 3 | 0.0556986 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0478505 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0464388 |
| NTN4 | netrin 4 | 0.0442516 |
| IL1B | interleukin 1, beta | 0.0436842 |
| RAD51B | RAD51 paralog B | 0.0430351 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0416208 |
| AADAC | arylacetamide deacetylase | 0.0411905 |
| RPS12 | ribosomal protein S12 | 0.039773 |
| KYNU | kynureninase | 0.0377355 |
| ECE1 | endothelin converting enzyme 1 | 0.0363241 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0359605 |
| VEGFA | vascular endothelial growth factor A | 0.0357337 |
| NRP1 | neuropilin 1 | 0.034018 |
| FAM20C | family with sequence similarity 20, member C | 0.0334108 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0331969 |
| INTS6 | integrator complex subunit 6 | 0.0324313 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0313996 |
| TGM2 | transglutaminase 2 | 0.0306888 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0295559 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0295149 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0286242 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0286038 |
| FNIP1 | folliculin interacting protein 1 | 0.0265634 |
| HDAC9 | histone deacetylase 9 | 0.0239317 |
| GLCCI1 | glucocorticoid induced 1 | 0.0237566 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0230773 |
| SVIL | supervillin | 0.0227816 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0218777 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0218356 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.0216347 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.021425 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0213105 |
| IFI44L | interferon-induced protein 44-like | 0.0209803 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0203754 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0203544 |
| RPS3 | ribosomal protein S3 | 0.020291 |
| CDH13 | cadherin 13 | 0.0201758 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0200826 |
| RPS2 | ribosomal protein S2 | 0.0200075 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0197045 |
| CDCP1 | CUB domain containing protein 1 | 0.0192243 |
| TGFB1 | transforming growth factor, beta 1 | 0.0188759 |
| GPHN | gephyrin | 0.0187992 |
| RPS8 | ribosomal protein S8 | 0.0182859 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0180613 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0179216 |
| R3HDM2 | R3H domain containing 2 | 0.0178896 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0177356 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0173293 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0171421 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.01709 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0169664 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0168765 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0168753 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0167134 |
| VMP1 | vacuole membrane protein 1 | 0.016692 |
| MEIS1 | Meis homeobox 1 | 0.0165641 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0162506 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0162371 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0161488 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0161226 |
| B2M | beta-2-microglobulin | 0.0158622 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0158023 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0157871 |
| LOXL2 | lysyl oxidase-like 2 | 0.0153809 |
| EGFR | epidermal growth factor receptor | 0.0152225 |
| AVIL | advillin | 0.0151 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0148698 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.014823 |
| ANK2 | ankyrin 2, neuronal | 0.0148056 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0146335 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.014629 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0145465 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0144764 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0143049 |
| SP100 | SP100 nuclear antigen | 0.0142555 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0142158 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.014175 |
| FMNL2 | formin-like 2 | 0.014124 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0140669 |
| NOTCH2 | notch 2 | 0.0140037 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.013973 |
| ITGA1 | integrin, alpha 1 | 0.0139113 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0137768 |
| CEP250 | centrosomal protein 250kDa | 0.0137593 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0137242 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0136856 |
| ATM | ATM serine/threonine kinase | 0.0136386 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0135225 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.0134722 |
| AUTS2 | autism susceptibility candidate 2 | 0.0133779 |
| HMGA1 | high mobility group AT-hook 1 | 0.0133663 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 | 0.0133607 |
| RORA | RAR-related orphan receptor A | 0.0133336 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.241346 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.195754 |
| FN1 | fibronectin 1 | -0.161352 |
| VIM | vimentin | -0.126236 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.12587 |
| LOX | lysyl oxidase | -0.113727 |
| PTMA | prothymosin, alpha | -0.0948817 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.09459 |
| S100A6 | S100 calcium binding protein A6 | -0.0914566 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.083828 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0829295 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0782567 |
| OSMR | oncostatin M receptor | -0.072909 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0694644 |
| LMAN1 | lectin, mannose-binding, 1 | -0.068087 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0669842 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0667567 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0661807 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0625443 |
| RBM39 | RNA binding motif protein 39 | -0.0586449 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0581178 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0572562 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0559663 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0533137 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0524618 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0515688 |
| RPLP1 | ribosomal protein, large, P1 | -0.0513532 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0499649 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0489832 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0475189 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0459366 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0456322 |
| RPS21 | ribosomal protein S21 | -0.0450411 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0440312 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.043983 |
| MEF2A | myocyte enhancer factor 2A | -0.0437413 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.043291 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0427265 |
| IER3 | immediate early response 3 | -0.0426555 |
| TMEM263 | transmembrane protein 263 | -0.0420977 |
| GNAS | GNAS complex locus | -0.0416019 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0413977 |
| S100A10 | S100 calcium binding protein A10 | -0.0413748 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0412444 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0396007 |
| ANXA2 | annexin A2 | -0.0394194 |
| CD44 | CD44 molecule (Indian blood group) | -0.0393643 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0391678 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0380247 |
| CALU | calumenin | -0.0375789 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0375579 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.037186 |
| NDRG1 | N-myc downstream regulated 1 | -0.0370744 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0368072 |
| GOLGA4 | golgin A4 | -0.0363193 |
| FLNB | filamin B, beta | -0.0355755 |
| FTL | ferritin, light polypeptide | -0.0351159 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0350263 |
| PRRC2C | proline-rich coiled-coil 2C | -0.034778 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.034622 |
| MT2A | metallothionein 2A | -0.0343099 |
| RPS19 | ribosomal protein S19 | -0.034244 |
| RPL34 | ribosomal protein L34 | -0.0331757 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0330235 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0329719 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0329547 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0323005 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0320899 |
| H1-0 | H1.0 linker histone | -0.0320579 |
| RPL35A | ribosomal protein L35a | -0.0316373 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0314545 |
| PRSS23 | protease, serine, 23 | -0.0312888 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0311237 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0310004 |
| TMSB4X | thymosin beta 4, X-linked | -0.0306098 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0303673 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0301924 |
| MAP1B | microtubule-associated protein 1B | -0.0300751 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0299772 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0298949 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0296246 |
| TNNC1 | troponin C type 1 (slow) | -0.0295762 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0293447 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0291762 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0291039 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.028881 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0287148 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0286022 |
| RIOK3 | RIO kinase 3 | -0.0285162 |
| ADM | adrenomedullin | -0.0282212 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0282161 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0279864 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0279061 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0278673 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0276802 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0276694 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0276533 |
| HAS2 | hyaluronan synthase 2 | -0.0276065 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0276037 |
| RAI1 | retinoic acid induced 1 | -0.0274628 |
