| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 4EGI-1 perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 4EGI-1_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.072161 |
| RPS12 | ribosomal protein S12 | 0.0486325 |
| GDA | guanine deaminase | 0.0460029 |
| FMNL2 | formin-like 2 | 0.0341161 |
| RPS2 | ribosomal protein S2 | 0.0333684 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0333426 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0320384 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0312356 |
| SQSTM1 | sequestosome 1 | 0.0311082 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.030685 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0279614 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0267918 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0256682 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0249229 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.024194 |
| RPL3 | ribosomal protein L3 | 0.0239809 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0216203 |
| CD109 | CD109 molecule | 0.0215054 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0213123 |
| RPS3 | ribosomal protein S3 | 0.0211348 |
| NTN4 | netrin 4 | 0.0203298 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0202337 |
| JMJD1C | jumonji domain containing 1C | 0.0192945 |
| HSPA8 | heat shock 70kDa protein 8 | 0.019285 |
| TPM3 | tropomyosin 3 | 0.0189763 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0184295 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0182835 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0181512 |
| RPS8 | ribosomal protein S8 | 0.0180249 |
| STC1 | stanniocalcin 1 | 0.0167771 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0167604 |
| RACK1 | receptor for activated C kinase 1 | 0.016643 |
| CTSL | cathepsin L | 0.0165854 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0165851 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0164124 |
| RPS27 | ribosomal protein S27 | 0.0161554 |
| CD44 | CD44 molecule (Indian blood group) | 0.0161052 |
| PCBP2 | poly(rC) binding protein 2 | 0.0151705 |
| SMAD2 | SMAD family member 2 | 0.0151602 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.015074 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0150455 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0143882 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0138837 |
| ANXA5 | annexin A5 | 0.0137632 |
| MCL1 | myeloid cell leukemia 1 | 0.01376 |
| ESM1 | endothelial cell-specific molecule 1 | 0.0133934 |
| BPTF | bromodomain PHD finger transcription factor | 0.0129114 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0128897 |
| BMP6 | bone morphogenetic protein 6 | 0.0127489 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0124715 |
| GOLGB1 | golgin B1 | 0.0123818 |
| VMP1 | vacuole membrane protein 1 | 0.0122451 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0121232 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0118739 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0118292 |
| RPS7 | ribosomal protein S7 | 0.0117148 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.011702 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0115926 |
| RPS17 | ribosomal protein S17 | 0.0114566 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | 0.0114253 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0113051 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0112782 |
| COPA | coatomer protein complex, subunit alpha | 0.0109037 |
| SLK | STE20-like kinase | 0.0109021 |
| KYNU | kynureninase | 0.0106879 |
| RPS18 | ribosomal protein S18 | 0.0103897 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0103627 |
| MFSD12 | major facilitator superfamily domain containing 12 | 0.0102045 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0101437 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.00988546 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.00980057 |
| CUL4A | cullin 4A | 0.00979586 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.00973904 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.00970774 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.00969323 |
| FNBP4 | formin binding protein 4 | 0.009547 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.00953396 |
| GPATCH2L | G patch domain containing 2-like | 0.00937488 |
| DSPP | dentin sialophosphoprotein | 0.00935341 |
| DST | dystonin | 0.00933525 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.00928099 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.00916434 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.00910684 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.00905119 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0088982 |
| RPL14 | ribosomal protein L14 | 0.00878427 |
| LITAF | lipopolysaccharide-induced TNF factor | 0.00878397 |
| SEPTIN9 | septin 9 | 0.00877381 |
| LMO7 | LIM domain 7 | 0.00873875 |
| ENAH | enabled homolog (Drosophila) | 0.00867135 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.00866887 |
| APP | amyloid beta (A4) precursor protein | 0.00863638 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.00862567 |
| FNIP1 | folliculin interacting protein 1 | 0.00861943 |
| WDR43 | WD repeat domain 43 | 0.00855049 |
| RPL4 | ribosomal protein L4 | 0.00838639 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.00830497 |
| RAB3B | RAB3B, member RAS oncogene family | 0.0082195 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.00818494 |
| RAI14 | retinoic acid induced 14 | 0.00811847 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.25524 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.191248 |
| TMSB10 | thymosin beta 10 | -0.164351 |
| PTMA | prothymosin, alpha | -0.0986544 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0871044 |
| EFNA5 | ephrin-A5 | -0.0798263 |
| RPLP1 | ribosomal protein, large, P1 | -0.0790701 |
| FN1 | fibronectin 1 | -0.0779807 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0662428 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.065519 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0629273 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0606603 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0564128 |
| PDE10A | phosphodiesterase 10A | -0.0561121 |
| GNAS | GNAS complex locus | -0.0540538 |
| FTL | ferritin, light polypeptide | -0.0528902 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0488418 |
| SRGN | serglycin | -0.0471259 |
| RPL35A | ribosomal protein L35a | -0.0462633 |
| PGK1 | phosphoglycerate kinase 1 | -0.0436875 |
| MYOF | myoferlin | -0.0415042 |
| COL5A2 | collagen, type V, alpha 2 | -0.0398452 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0396512 |
| RGS2 | regulator of G-protein signaling 2 | -0.03875 |
| PTGR1 | prostaglandin reductase 1 | -0.0385216 |
| S100A6 | S100 calcium binding protein A6 | -0.0374075 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0361531 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0347665 |
| PRELID2 | PRELI domain containing 2 | -0.0333723 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0332593 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0330163 |
| RPS21 | ribosomal protein S21 | -0.0327167 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0327027 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0323385 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0321996 |
| RPS19 | ribosomal protein S19 | -0.0321868 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0314481 |
| TXNRD1 | thioredoxin reductase 1 | -0.0313362 |
| LMNA | lamin A/C | -0.0309972 |
| MT2A | metallothionein 2A | -0.0307056 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0304515 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0300374 |
| KPNB1 | karyopherin (importin) beta 1 | -0.029635 |
| S100A10 | S100 calcium binding protein A10 | -0.0294224 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0290698 |
| ASPH | aspartate beta-hydroxylase | -0.0289412 |
| LOC112694756 | uncharaterized LOC112694756 | -0.028345 |
| NRCAM | neuronal cell adhesion molecule | -0.0272609 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0272433 |
| RPS6 | ribosomal protein S6 | -0.0270863 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0270239 |
| CANX | calnexin | -0.026872 |
| RPL19 | ribosomal protein L19 | -0.0267408 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.02647 |
| RPLP0 | ribosomal protein, large, P0 | -0.0259454 |
| OGA | O-GlcNAcase | -0.025913 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0254885 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0253163 |
| RPS23 | ribosomal protein S23 | -0.0253004 |
| HLA-A | major histocompatibility complex, class I, A | -0.0246356 |
| RPS24 | ribosomal protein S24 | -0.0238642 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0236405 |
| PALLD | palladin, cytoskeletal associated protein | -0.0231305 |
| IER3 | immediate early response 3 | -0.0231134 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0229911 |
| PFN1 | profilin 1 | -0.0229392 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0228777 |
| RRBP1 | ribosome binding protein 1 | -0.0227467 |
| PKM | pyruvate kinase, muscle | -0.0225347 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0221808 |
| PRDX1 | peroxiredoxin 1 | -0.0216315 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0213606 |
| MT1X | metallothionein 1X | -0.0209379 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0207311 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.020649 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | -0.0205631 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0203081 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0200911 |
| VDAC1 | voltage-dependent anion channel 1 | -0.019927 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.019493 |
| TUBA1B | tubulin, alpha 1b | -0.0190884 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0190207 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.019001 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.0189492 |
| RPLP2 | ribosomal protein, large, P2 | -0.0188814 |
| RPS28 | ribosomal protein S28 | -0.0187977 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0186288 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0184856 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0176572 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0176516 |
| TMSB4X | thymosin beta 4, X-linked | -0.0174452 |
| CDK6 | cyclin-dependent kinase 6 | -0.0172347 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0172119 |
| LDHA | lactate dehydrogenase A | -0.0171616 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.0171023 |
| MFF | mitochondrial fission factor | -0.0170872 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0170645 |
| HLA-B | major histocompatibility complex, class I, B | -0.0170433 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0169103 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0169075 |
