| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 4EGI-1 perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 4EGI-1_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.0465152 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0448969 |
| DST | dystonin | 0.041059 |
| HDAC9 | histone deacetylase 9 | 0.0403287 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0338707 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0301731 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0290041 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0284289 |
| ANK2 | ankyrin 2, neuronal | 0.0282685 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0247347 |
| UBN2 | ubinuclein 2 | 0.0239772 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0232299 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0223693 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0222996 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0216125 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.021244 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.020865 |
| SMYD3 | SET and MYND domain containing 3 | 0.0208027 |
| NCKAP1 | NCK-associated protein 1 | 0.0205731 |
| PARD3 | par-3 family cell polarity regulator | 0.020507 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0204344 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0202444 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0197312 |
| VMP1 | vacuole membrane protein 1 | 0.0195852 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.019511 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0190428 |
| COL11A1 | collagen, type XI, alpha 1 | 0.0188752 |
| HMGA2 | high mobility group AT-hook 2 | 0.0181997 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0179687 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0177996 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0177572 |
| FN1 | fibronectin 1 | 0.0177242 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0176764 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0173384 |
| APP | amyloid beta (A4) precursor protein | 0.017174 |
| BRD2 | bromodomain containing 2 | 0.0169017 |
| INTS6 | integrator complex subunit 6 | 0.0161768 |
| PARD3B | par-3 family cell polarity regulator beta | 0.016124 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | 0.0161196 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0157395 |
| CTBP2 | C-terminal binding protein 2 | 0.0156073 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0152989 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 0.0152972 |
| HYOU1 | hypoxia up-regulated 1 | 0.0152155 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0151682 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0151133 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0150388 |
| FIGN | fidgetin | 0.0149416 |
| PCDH18 | protocadherin 18 | 0.0148804 |
| RUNX1 | runt-related transcription factor 1 | 0.0147645 |
| ZNF608 | zinc finger protein 608 | 0.0146965 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0146777 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0145304 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0145057 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0143614 |
| SERTAD2 | SERTA domain containing 2 | 0.0142847 |
| RYK | receptor-like tyrosine kinase | 0.0141557 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0139416 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0138777 |
| IGF2R | insulin-like growth factor 2 receptor | 0.01371 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0135862 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0134806 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0134664 |
| CDC73 | cell division cycle 73 | 0.013397 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0133394 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0130724 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0130672 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0127912 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0127609 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0126658 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0126505 |
| FOXO1 | forkhead box O1 | 0.0126064 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.0125791 |
| NEK7 | NIMA-related kinase 7 | 0.0124615 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0124599 |
| DNAH11 | dynein, axonemal, heavy chain 11 | 0.012451 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0124311 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0124206 |
| RANBP9 | RAN binding protein 9 | 0.0124101 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0123576 |
| DICER1 | dicer 1, ribonuclease type III | 0.012355 |
| NCOA2 | nuclear receptor coactivator 2 | 0.0122614 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0122028 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0121822 |
| PCMTD1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 | 0.012002 |
| JMJD1C | jumonji domain containing 1C | 0.0119512 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0118726 |
| CEP112 | centrosomal protein 112kDa | 0.0118668 |
| EP300 | E1A binding protein p300 | 0.0117951 |
| HSPA8 | heat shock 70kDa protein 8 | 0.011741 |
| RPL3 | ribosomal protein L3 | 0.0117373 |
| NDUFAF2 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 | 0.0116563 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0116137 |
| CXXC4 | CXXC finger protein 4 | 0.0116041 |
| ZNF451 | zinc finger protein 451 | 0.0114954 |
| UBL3 | ubiquitin-like 3 | 0.0114338 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0114277 |
| MIPOL1 | mirror-image polydactyly 1 | 0.0113241 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0113094 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0113043 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.263337 |
| TMSB10 | thymosin beta 10 | -0.173899 |
| PTMA | prothymosin, alpha | -0.167845 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.132498 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.130838 |
| PCDH9 | protocadherin 9 | -0.12656 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.119013 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.110418 |
| GPC3 | glypican 3 | -0.0988614 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0948741 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0920488 |
| COL1A2 | collagen, type I, alpha 2 | -0.087354 |
| COL3A1 | collagen, type III, alpha 1 | -0.0845799 |
| GNAS | GNAS complex locus | -0.0843541 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0826017 |
| RPS6 | ribosomal protein S6 | -0.0810358 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0779529 |
| PHIP | pleckstrin homology domain interacting protein | -0.0772246 |
| COL5A2 | collagen, type V, alpha 2 | -0.0764609 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0760485 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0740521 |
| RPL35A | ribosomal protein L35a | -0.0700349 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0638899 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.063842 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0636913 |
| RPLP1 | ribosomal protein, large, P1 | -0.0584931 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.056702 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0559049 |
| ACTG1 | actin gamma 1 | -0.0550305 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0541111 |
| RPS21 | ribosomal protein S21 | -0.0534955 |
| PFN1 | profilin 1 | -0.0532194 |
| RPS8 | ribosomal protein S8 | -0.0531716 |
| ANKRD12 | ankyrin repeat domain 12 | -0.051887 |
| PEG10 | paternally expressed 10 | -0.0517309 |
| RPS16 | ribosomal protein S16 | -0.0510914 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0485243 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0466605 |
| PGK1 | phosphoglycerate kinase 1 | -0.0460681 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0458208 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0451927 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0446414 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0444821 |
| SFRP4 | secreted frizzled-related protein 4 | -0.0438077 |
| TMSB4X | thymosin beta 4, X-linked | -0.0436933 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0428529 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0418936 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0415216 |
| MKI67 | marker of proliferation Ki-67 | -0.0414513 |
| RPLP0 | ribosomal protein, large, P0 | -0.0399749 |
| SOX2 | SRY (sex determining region Y)-box 2 | -0.039514 |
| EMP1 | epithelial membrane protein 1 | -0.0394817 |
| FTL | ferritin, light polypeptide | -0.0388518 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0385526 |
| RPS19 | ribosomal protein S19 | -0.038324 |
| RAI1 | retinoic acid induced 1 | -0.0379118 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0377865 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0372401 |
| S100A10 | S100 calcium binding protein A10 | -0.0368605 |
| H1-0 | H1.0 linker histone | -0.0365635 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0365377 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0363513 |
| TOX | thymocyte selection-associated high mobility group box | -0.0361888 |
| NRG1 | neuregulin 1 | -0.0361241 |
| RPL19 | ribosomal protein L19 | -0.036067 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0356187 |
| RPS24 | ribosomal protein S24 | -0.0354461 |
| RPL12 | ribosomal protein L12 | -0.0354034 |
| RPL11 | ribosomal protein L11 | -0.0353471 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0352629 |
| METAP2 | methionyl aminopeptidase 2 | -0.0346792 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0345423 |
| SEPTIN7 | septin 7 | -0.0343149 |
| POTEF | POTE ankyrin domain family, member F | -0.0341593 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0336212 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0332892 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0331738 |
| MAP4 | microtubule-associated protein 4 | -0.0330577 |
| THOC2 | THO complex 2 | -0.0330477 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0329909 |
| DEK | DEK proto-oncogene | -0.0327315 |
| RPL34 | ribosomal protein L34 | -0.032728 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.0325195 |
| PRELID2 | PRELI domain containing 2 | -0.032167 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0321401 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0318753 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0317537 |
| RFPL4B | ret finger protein-like 4B | -0.0317154 |
| RPL23 | ribosomal protein L23 | -0.0315771 |
| RPS13 | ribosomal protein S13 | -0.0315293 |
| RPL5 | ribosomal protein L5 | -0.0313186 |
| TUBA1B | tubulin, alpha 1b | -0.0312614 |
| SNX6 | sorting nexin 6 | -0.0311538 |
| TENM3 | teneurin transmembrane protein 3 | -0.0309421 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.03087 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0306312 |
| CBX3 | chromobox homolog 3 | -0.0304067 |
| YBX1 | Y box binding protein 1 | -0.0303824 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 | -0.0302074 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0300577 |
