| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 4EGI-1 perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 4EGI-1_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.306189 |
| VCL | vinculin | 0.253888 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.152089 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.138406 |
| SLC35F3 | solute carrier family 35, member F3 | 0.122847 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.121188 |
| DST | dystonin | 0.107962 |
| EGFR | epidermal growth factor receptor | 0.101219 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0989959 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0901528 |
| AHNAK | AHNAK nucleoprotein | 0.083938 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0827423 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0822411 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0773651 |
| HMGA2 | high mobility group AT-hook 2 | 0.0767618 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0741471 |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | 0.066206 |
| NAV2 | neuron navigator 2 | 0.0595979 |
| PTK2 | protein tyrosine kinase 2 | 0.0593768 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0571623 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0567614 |
| ACTG1 | actin gamma 1 | 0.0558817 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0531236 |
| SAMD4B | sterile alpha motif domain containing 4B | 0.0520656 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0508283 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0508061 |
| ASPH | aspartate beta-hydroxylase | 0.0506286 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0500751 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0500567 |
| INTS6 | integrator complex subunit 6 | 0.0484519 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0483179 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.047781 |
| MYO1E | myosin IE | 0.0477521 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.047466 |
| SMYD3 | SET and MYND domain containing 3 | 0.047141 |
| EXOC4 | exocyst complex component 4 | 0.0465071 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0461875 |
| MCL1 | myeloid cell leukemia 1 | 0.0461324 |
| TPM1 | tropomyosin 1 (alpha) | 0.0457105 |
| APP | amyloid beta (A4) precursor protein | 0.0455121 |
| ANO6 | anoctamin 6 | 0.0449865 |
| MYOF | myoferlin | 0.0448121 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0442118 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0438629 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0435948 |
| CD44 | CD44 molecule (Indian blood group) | 0.043511 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0434486 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0430808 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0429055 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0424754 |
| SMAD3 | SMAD family member 3 | 0.0410702 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0406851 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0406416 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0401675 |
| ATXN1 | ataxin 1 | 0.0401317 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0401302 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0400316 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0400019 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0386407 |
| ZNF780B | zinc finger protein 780B | 0.0385414 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0384376 |
| TNS3 | tensin 3 | 0.0384031 |
| EHBP1 | EH domain binding protein 1 | 0.0379185 |
| RASAL2 | RAS protein activator like 2 | 0.0378655 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0377487 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0373323 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0369777 |
| EGR1 | early growth response 1 | 0.0368145 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0367329 |
| SBF2 | SET binding factor 2 | 0.0364236 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0358639 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0355058 |
| VMP1 | vacuole membrane protein 1 | 0.035483 |
| SFTPA2 | surfactant protein A2 | 0.0351127 |
| NUP98 | nucleoporin 98kDa | 0.034908 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0340393 |
| EFNA5 | ephrin-A5 | 0.0337838 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0337599 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0337304 |
| RAD51B | RAD51 paralog B | 0.0332056 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0331465 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0331028 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0330619 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0327192 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0326117 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0325834 |
| PDE10A | phosphodiesterase 10A | 0.0325719 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0324515 |
| RPS12 | ribosomal protein S12 | 0.0319232 |
| SQSTM1 | sequestosome 1 | 0.0318882 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.031872 |
| ATG7 | autophagy related 7 | 0.0317331 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0312151 |
| WDR27 | WD repeat domain 27 | 0.0310837 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0310382 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.030911 |
| ZNF407 | zinc finger protein 407 | 0.0300061 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0299337 |
| ATP9B | ATPase, class II, type 9B | 0.0298273 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0289674 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.192347 |
| PTMA | prothymosin, alpha | -0.170848 |
| VIM | vimentin | -0.0850054 |
| TMSB10 | thymosin beta 10 | -0.0846375 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0776423 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0713468 |
| FBL | fibrillarin | -0.0672276 |
| S100A6 | S100 calcium binding protein A6 | -0.0605279 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.055461 |
| RTN4 | reticulon 4 | -0.0506679 |
| TXNRD1 | thioredoxin reductase 1 | -0.0496992 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0460878 |
| TMEM41B | transmembrane protein 41B | -0.0459238 |
| FTL | ferritin, light polypeptide | -0.0452902 |
| RPL35A | ribosomal protein L35a | -0.0449054 |
| RPS16 | ribosomal protein S16 | -0.0440159 |
| YBX1 | Y box binding protein 1 | -0.0422336 |
| SNX14 | sorting nexin 14 | -0.0419995 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0419022 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0397033 |
| FOSL1 | FOS-like antigen 1 | -0.0383494 |
| RPLP0 | ribosomal protein, large, P0 | -0.0363219 |
| RPLP1 | ribosomal protein, large, P1 | -0.0353878 |
| TMEM123 | transmembrane protein 123 | -0.0352053 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0349276 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0345478 |
| ZNF292 | zinc finger protein 292 | -0.033595 |
| PFN1 | profilin 1 | -0.0324448 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0321769 |
| WDR45B | WD repeat domain 45B | -0.0316057 |
| ANLN | anillin, actin binding protein | -0.0314423 |
| GOLGA4 | golgin A4 | -0.0314318 |
| SPAG9 | sperm associated antigen 9 | -0.030696 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0298124 |
| NOP58 | NOP58 ribonucleoprotein | -0.0294035 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0291848 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0289573 |
| USP3 | ubiquitin specific peptidase 3 | -0.0288638 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0285559 |
| S100A10 | S100 calcium binding protein A10 | -0.0279051 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0278215 |
| GNAS | GNAS complex locus | -0.0273052 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.026314 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0262965 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0254952 |
| ADM | adrenomedullin | -0.0253885 |
| RPS5 | ribosomal protein S5 | -0.0251946 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0247962 |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | -0.0243365 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0242287 |
| ANXA2 | annexin A2 | -0.0237496 |
| MATR3 | matrin 3 | -0.0237329 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0235981 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0235707 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0235302 |
| CD109 | CD109 molecule | -0.0232859 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0231653 |
| SEPTIN7 | septin 7 | -0.0231083 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0227838 |
| EIF3K | eukaryotic translation initiation factor 3, subunit K | -0.0222908 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.0221049 |
| RPS6 | ribosomal protein S6 | -0.0218188 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0215521 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0214922 |
| RPLP2 | ribosomal protein, large, P2 | -0.0213312 |
| MORF4L2 | mortality factor 4 like 2 | -0.021141 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0211154 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0210291 |
| RBM25 | RNA binding motif protein 25 | -0.0209913 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0207704 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0206907 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0204928 |
| WASF2 | WAS protein family, member 2 | -0.0204685 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0203486 |
| NUP58 | nucleoporin 58 | -0.0203385 |
| SRP54 | signal recognition particle 54kDa | -0.0200666 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | -0.0200167 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.0199726 |
| ZFP36 | ZFP36 ring finger protein | -0.019967 |
| INSIG1 | insulin induced gene 1 | -0.0199562 |
| RPS19 | ribosomal protein S19 | -0.0198622 |
| FDPS | farnesyl diphosphate synthase | -0.0198179 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.0197603 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0197286 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0196567 |
| CBX3 | chromobox homolog 3 | -0.019412 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0192981 |
| ARRDC3 | arrestin domain containing 3 | -0.0189077 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0187249 |
| PGK1 | phosphoglycerate kinase 1 | -0.0184412 |
| SUCO | SUN domain containing ossification factor | -0.018297 |
| OGA | O-GlcNAcase | -0.0181859 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0181699 |
| CTDSPL2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 | -0.0180342 |
| SQLE | squalene epoxidase | -0.0177921 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.01763 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.017462 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0174581 |
| RPS21 | ribosomal protein S21 | -0.0174423 |
| FAM162A | family with sequence similarity 162, member A | -0.017439 |
