| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 4EGI-1 perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 4EGI-1_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ACTG1 | actin gamma 1 | 0.178097 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.165443 |
| LMO7 | LIM domain 7 | 0.137227 |
| LAMB3 | laminin, beta 3 | 0.114443 |
| LAMC2 | laminin, gamma 2 | 0.0932665 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0766173 |
| SQSTM1 | sequestosome 1 | 0.0757545 |
| INTS6 | integrator complex subunit 6 | 0.0747409 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0737422 |
| EGFR | epidermal growth factor receptor | 0.0734991 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0728348 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0725304 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0702002 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.070103 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0698865 |
| SVIL | supervillin | 0.069756 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.068537 |
| DSPP | dentin sialophosphoprotein | 0.0666377 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0632941 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0569392 |
| MYO5B | myosin VB | 0.0555916 |
| SMAD3 | SMAD family member 3 | 0.0554661 |
| HDAC9 | histone deacetylase 9 | 0.0548199 |
| GOLGB1 | golgin B1 | 0.0543631 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0542677 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0529423 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0519451 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0506653 |
| PATJ | PATJ crumbs cell polarity complex component | 0.049697 |
| RPS8 | ribosomal protein S8 | 0.0488181 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0478449 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0469056 |
| TJP1 | tight junction protein 1 | 0.0464506 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0460316 |
| SYT14 | synaptotagmin XIV | 0.0457464 |
| KRT8 | keratin 8, type II | 0.0449745 |
| RPS12 | ribosomal protein S12 | 0.0428347 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0421079 |
| PLSCR1 | phospholipid scramblase 1 | 0.0412254 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0406902 |
| CD44 | CD44 molecule (Indian blood group) | 0.0403432 |
| VEGFA | vascular endothelial growth factor A | 0.0402105 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0401185 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0396476 |
| FMNL2 | formin-like 2 | 0.0383576 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0382806 |
| HMGA2 | high mobility group AT-hook 2 | 0.0377089 |
| MYO1E | myosin IE | 0.0371311 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0370109 |
| RPS3 | ribosomal protein S3 | 0.0369226 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0362968 |
| NAV2 | neuron navigator 2 | 0.0358971 |
| FN1 | fibronectin 1 | 0.0358016 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0337391 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0335592 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.033547 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0330004 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0326474 |
| DOCK9 | dedicator of cytokinesis 9 | 0.032331 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0322944 |
| SLC35F3 | solute carrier family 35, member F3 | 0.032078 |
| RACK1 | receptor for activated C kinase 1 | 0.0318043 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0313265 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0312521 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0312249 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0311385 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0309031 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0309024 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0298943 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0297785 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0295347 |
| RPL37A | ribosomal protein L37a | 0.0294482 |
| MUC16 | mucin 16, cell surface associated | 0.0292341 |
| MUC4 | mucin 4, cell surface associated | 0.029165 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0291214 |
| RAD51B | RAD51 paralog B | 0.0290734 |
| BRD2 | bromodomain containing 2 | 0.0288625 |
| KLF6 | Kruppel-like factor 6 | 0.0287547 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0287361 |
| RPS17 | ribosomal protein S17 | 0.0284842 |
| SEPTIN9 | septin 9 | 0.0280733 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0279439 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0278668 |
| KRT18 | keratin 18, type I | 0.0278197 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.027775 |
| RASAL2 | RAS protein activator like 2 | 0.0277217 |
| DOCK1 | dedicator of cytokinesis 1 | 0.027537 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.027175 |
| SIK3 | SIK family kinase 3 | 0.0269555 |
| RPS2 | ribosomal protein S2 | 0.0268955 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.026665 |
| BPTF | bromodomain PHD finger transcription factor | 0.0264198 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0263935 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0263746 |
| SMYD3 | SET and MYND domain containing 3 | 0.0261784 |
| VMP1 | vacuole membrane protein 1 | 0.0258797 |
| FNIP1 | folliculin interacting protein 1 | 0.0257442 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0256154 |
| RPL31 | ribosomal protein L31 | 0.0254158 |
| PLEC | plectin | 0.0253567 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.347096 |
| PTMA | prothymosin, alpha | -0.166124 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.140471 |
| TMSB10 | thymosin beta 10 | -0.109447 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0818381 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0789318 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0776845 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.076115 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0744904 |
| ANLN | anillin, actin binding protein | -0.0699678 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0652486 |
| KRT19 | keratin 19, type I | -0.0651971 |
| FAM3C | family with sequence similarity 3, member C | -0.0623292 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0588532 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0585647 |
| TMEM123 | transmembrane protein 123 | -0.0564723 |
| LDHA | lactate dehydrogenase A | -0.0528037 |
| NDRG1 | N-myc downstream regulated 1 | -0.0525859 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0506401 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0504324 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.049126 |
| S100A6 | S100 calcium binding protein A6 | -0.0490531 |
| PGK1 | phosphoglycerate kinase 1 | -0.0477806 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0446638 |
| FOSL1 | FOS-like antigen 1 | -0.0445986 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.042973 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0428863 |
| RLF | rearranged L-myc fusion | -0.0407256 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0398881 |
| DIAPH3 | diaphanous-related formin 3 | -0.0397581 |
| MKI67 | marker of proliferation Ki-67 | -0.0396765 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0396201 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0394813 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0387223 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0387003 |
| RBM39 | RNA binding motif protein 39 | -0.0378687 |
| OGA | O-GlcNAcase | -0.0377205 |
| GOLGA4 | golgin A4 | -0.0376934 |
| CD2AP | CD2-associated protein | -0.0376685 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0375782 |
| TFG | TRK-fused gene | -0.0372645 |
| HMGB2 | high mobility group box 2 | -0.0355092 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0354527 |
| ECT2 | epithelial cell transforming 2 | -0.0354324 |
| XPO1 | exportin 1 | -0.0340523 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0338861 |
| WDR45B | WD repeat domain 45B | -0.0335239 |
| TPI1 | triosephosphate isomerase 1 | -0.0330091 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0329492 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0326497 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0326166 |
| TMSB4X | thymosin beta 4, X-linked | -0.032571 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0323604 |
| NFIB | nuclear factor I/B | -0.0323172 |
| CENPF | centromere protein F, 350/400kDa | -0.0320969 |
| S100A10 | S100 calcium binding protein A10 | -0.0317602 |
| MT2A | metallothionein 2A | -0.0316972 |
| RPLP1 | ribosomal protein, large, P1 | -0.0315755 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0315467 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0314224 |
| CALR | calreticulin | -0.0313293 |
| RTN4 | reticulon 4 | -0.0312307 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0311803 |
| RBM25 | RNA binding motif protein 25 | -0.0310681 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0308866 |
| EPCAM | epithelial cell adhesion molecule | -0.0303366 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0301014 |
| PKM | pyruvate kinase, muscle | -0.0299482 |
| FCHSD2 | FCH and double SH3 domains 2 | -0.0293653 |
| TXNIP | thioredoxin interacting protein | -0.0289221 |
| DEK | DEK proto-oncogene | -0.0285672 |
| CANX | calnexin | -0.028375 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0282079 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0281466 |
| PLAT | plasminogen activator, tissue | -0.0279402 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0273723 |
| EHF | ets homologous factor | -0.027365 |
| SEPTIN7 | septin 7 | -0.027281 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0272411 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0269987 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0269427 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0269169 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0267716 |
| H3-3B | H3.3 histone B | -0.026588 |
| USP3 | ubiquitin specific peptidase 3 | -0.0264635 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.0264288 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0261577 |
| RIOK3 | RIO kinase 3 | -0.0259966 |
| TOP1 | topoisomerase (DNA) I | -0.0259221 |
| SETD5 | SET domain containing 5 | -0.0258802 |
| EMP1 | epithelial membrane protein 1 | -0.0257584 |
| PDCD10 | programmed cell death 10 | -0.0255245 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0253954 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0252522 |
| YBX3 | Y box binding protein 3 | -0.0251946 |
| ANXA2 | annexin A2 | -0.0251511 |
| ADM | adrenomedullin | -0.0250339 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0249713 |
| PDE8A | phosphodiesterase 8A | -0.0249658 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0248375 |
