| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 4EGI-1 perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 4EGI-1_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STC1 | stanniocalcin 1 | 0.0943906 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.056849 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0524413 |
| HDAC9 | histone deacetylase 9 | 0.0470687 |
| NAV2 | neuron navigator 2 | 0.0429791 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0409715 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0403855 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0369145 |
| FHIT | fragile histidine triad | 0.0310561 |
| SMAD3 | SMAD family member 3 | 0.0289936 |
| EML5 | echinoderm microtubule associated protein like 5 | 0.0285588 |
| AGBL1 | ATP/GTP binding protein-like 1 | 0.0282451 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0281374 |
| SP100 | SP100 nuclear antigen | 0.027458 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0271525 |
| FNIP1 | folliculin interacting protein 1 | 0.024765 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0244129 |
| FAT1 | FAT atypical cadherin 1 | 0.0232249 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0232072 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0231461 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0226807 |
| HMGA2 | high mobility group AT-hook 2 | 0.0225186 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0220776 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0219646 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0215729 |
| MMP12 | matrix metallopeptidase 12 | 0.0211921 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0206702 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0200654 |
| TMEM132D | transmembrane protein 132D | 0.0200453 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0197696 |
| VEGFA | vascular endothelial growth factor A | 0.0191749 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0181456 |
| FAM20C | family with sequence similarity 20, member C | 0.0180821 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0178729 |
| FMNL2 | formin-like 2 | 0.0177226 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0175074 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0174273 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0173011 |
| COLEC10 | collectin sub-family member 10 (C-type lectin) | 0.0170999 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0168354 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.016823 |
| LYST | lysosomal trafficking regulator | 0.0168156 |
| PLSCR1 | phospholipid scramblase 1 | 0.0165383 |
| ARRDC3 | arrestin domain containing 3 | 0.0163395 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0158155 |
| MYOF | myoferlin | 0.0158027 |
| RND3 | Rho family GTPase 3 | 0.0157567 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0156692 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0155885 |
| CD109 | CD109 molecule | 0.0151459 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0148369 |
| IFI44L | interferon-induced protein 44-like | 0.0147524 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.014641 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0144998 |
| CCBE1 | collagen and calcium binding EGF domains 1 | 0.014404 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0143429 |
| MYO9A | myosin IXA | 0.0142891 |
| MED13L | mediator complex subunit 13-like | 0.0142455 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0141458 |
| KIAA1217 | KIAA1217 | 0.014024 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0139242 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0138951 |
| IL6ST | interleukin 6 signal transducer | 0.013867 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0137893 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0136528 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.01352 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0134535 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.013394 |
| CCDC138 | coiled-coil domain containing 138 | 0.0133567 |
| RYBP | RING1 and YY1 binding protein | 0.0132698 |
| ANXA5 | annexin A5 | 0.013255 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0132285 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0131573 |
| DTX3L | deltex 3 like, E3 ubiquitin ligase | 0.0129933 |
| PARD3 | par-3 family cell polarity regulator | 0.0127228 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0126691 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0125282 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0123446 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0123441 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0122903 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0117623 |
| PHF3 | PHD finger protein 3 | 0.011727 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.011589 |
| PGM3 | phosphoglucomutase 3 | 0.0114547 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0114458 |
| ZNF638 | zinc finger protein 638 | 0.0113222 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0112602 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0112544 |
| B2M | beta-2-microglobulin | 0.0112249 |
| AHR | aryl hydrocarbon receptor | 0.0111985 |
| ANK2 | ankyrin 2, neuronal | 0.0111835 |
| TDRD7 | tudor domain containing 7 | 0.0111467 |
| GPHN | gephyrin | 0.0109195 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0108813 |
| PCBP3 | poly(rC) binding protein 3 | 0.0107759 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0106178 |
| KYNU | kynureninase | 0.0105566 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.010544 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0104712 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0104197 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.298652 |
| VIM | vimentin | -0.20766 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.139459 |
| COL1A2 | collagen, type I, alpha 2 | -0.139139 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.107338 |
| COL1A1 | collagen, type I, alpha 1 | -0.106219 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0894739 |
| TMSB10 | thymosin beta 10 | -0.0813624 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0788362 |
| NDRG1 | N-myc downstream regulated 1 | -0.0727828 |
| FTL | ferritin, light polypeptide | -0.0694293 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0652898 |
| FRMD4A | FERM domain containing 4A | -0.0608318 |
| POTEF | POTE ankyrin domain family, member F | -0.0587412 |
| HLA-B | major histocompatibility complex, class I, B | -0.0573785 |
| TPM1 | tropomyosin 1 (alpha) | -0.0500351 |
| PTMA | prothymosin, alpha | -0.0497184 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0496988 |
| MT2A | metallothionein 2A | -0.0485895 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0481198 |
| PGK1 | phosphoglycerate kinase 1 | -0.0454992 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0450882 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0397462 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0388107 |
| COL5A1 | collagen, type V, alpha 1 | -0.0384098 |
| PKM | pyruvate kinase, muscle | -0.0380106 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0371256 |
| TPM4 | tropomyosin 4 | -0.0359908 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0358322 |
| RRBP1 | ribosome binding protein 1 | -0.0355433 |
| TMEM178B | transmembrane protein 178B | -0.0338454 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0330538 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.030696 |
| GNAS | GNAS complex locus | -0.0290984 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0283843 |
| SETD5 | SET domain containing 5 | -0.0280839 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0270058 |
| MEF2A | myocyte enhancer factor 2A | -0.0267939 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0266196 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0265827 |
| CALD1 | caldesmon 1 | -0.0259798 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0258118 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0257075 |
| ENO1 | enolase 1, (alpha) | -0.0256691 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0256198 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0255219 |
| TNNC1 | troponin C type 1 (slow) | -0.0254619 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.025087 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0250077 |
| CALR | calreticulin | -0.0245666 |
| CENPF | centromere protein F, 350/400kDa | -0.0232962 |
| EGR1 | early growth response 1 | -0.0227526 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.022655 |
| S100A6 | S100 calcium binding protein A6 | -0.0224214 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0217043 |
| RTN4 | reticulon 4 | -0.0216662 |
| HLA-A | major histocompatibility complex, class I, A | -0.021651 |
| VCAN | versican | -0.0214537 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0212485 |
| NRP1 | neuropilin 1 | -0.0211787 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.0209874 |
| MAP1B | microtubule-associated protein 1B | -0.0207635 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0205572 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0204056 |
| FBN1 | fibrillin 1 | -0.0203414 |
| RPL35A | ribosomal protein L35a | -0.0193299 |
| ACTG1 | actin gamma 1 | -0.0192572 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0191602 |
| MKI67 | marker of proliferation Ki-67 | -0.0189907 |
| NAV1 | neuron navigator 1 | -0.0184682 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0184213 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0182747 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0181845 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0180921 |
| PFN1 | profilin 1 | -0.0179784 |
| HLA-C | major histocompatibility complex, class I, C | -0.0177361 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0177048 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0174271 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0172685 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0171905 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0171836 |
| RPS21 | ribosomal protein S21 | -0.0169298 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.01689 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0168689 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0167069 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0166101 |
| ITGA11 | integrin, alpha 11 | -0.0164807 |
| CD63 | CD63 molecule | -0.0159834 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0159338 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0156506 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0155794 |
| LMNA | lamin A/C | -0.0155682 |
| S100A9 | S100 calcium binding protein A9 | -0.0154574 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0151255 |
| FKBP1A | FK506 binding protein 1A, 12kDa | -0.0150375 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0149855 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0149488 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0148894 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0148072 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0147499 |
