| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 4EGI-1 perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 4EGI-1_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | 0.272605 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.115738 |
| HDAC9 | histone deacetylase 9 | 0.109336 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0927199 |
| NAV2 | neuron navigator 2 | 0.0909204 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0868448 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0747332 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0703203 |
| KYNU | kynureninase | 0.0699499 |
| RND3 | Rho family GTPase 3 | 0.0652657 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0636191 |
| VEGFA | vascular endothelial growth factor A | 0.0596849 |
| FNIP1 | folliculin interacting protein 1 | 0.0570044 |
| CDH13 | cadherin 13 | 0.0564259 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0562307 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0520351 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0511727 |
| GPC6 | glypican 6 | 0.0510284 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0465887 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0446871 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0443022 |
| VCAN | versican | 0.0425204 |
| DUSP10 | dual specificity phosphatase 10 | 0.0411034 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0402472 |
| JMJD1C | jumonji domain containing 1C | 0.0397707 |
| TMEM132D | transmembrane protein 132D | 0.039545 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0387286 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0382006 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0378785 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0373892 |
| VMP1 | vacuole membrane protein 1 | 0.0371144 |
| SQSTM1 | sequestosome 1 | 0.0355322 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0336913 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0333228 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0332648 |
| FMNL2 | formin-like 2 | 0.0331511 |
| HMGA2 | high mobility group AT-hook 2 | 0.0330328 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0309326 |
| INTS6 | integrator complex subunit 6 | 0.0308321 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0305859 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0303708 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0294724 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0287805 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0284964 |
| GOLGB1 | golgin B1 | 0.0278258 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0275241 |
| ASPH | aspartate beta-hydroxylase | 0.0272232 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0267568 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0263875 |
| SPAG9 | sperm associated antigen 9 | 0.025958 |
| SFTPA2 | surfactant protein A2 | 0.0259477 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0258243 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0252666 |
| CTSB | cathepsin B | 0.0249463 |
| VAC14 | Vac14 homolog (S. cerevisiae) | 0.0248058 |
| AHR | aryl hydrocarbon receptor | 0.0246623 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0245729 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0242554 |
| MLPH | melanophilin | 0.0241028 |
| ERBIN | erbb2 interacting protein | 0.0238578 |
| APP | amyloid beta (A4) precursor protein | 0.0238457 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0236401 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0235478 |
| KLHL24 | kelch-like family member 24 | 0.0235387 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0231458 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0223893 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0219796 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | 0.0218748 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0215954 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0214545 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0206852 |
| FBXO32 | F-box protein 32 | 0.0206839 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0204356 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0199779 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0199281 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0198954 |
| FNIP2 | folliculin interacting protein 2 | 0.019612 |
| NOTCH2 | notch 2 | 0.0195657 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0194143 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0193429 |
| MYOF | myoferlin | 0.0192653 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0192593 |
| USP53 | ubiquitin specific peptidase 53 | 0.0189411 |
| PHF3 | PHD finger protein 3 | 0.0187794 |
| GPR176 | G protein-coupled receptor 176 | 0.0187496 |
| PGM3 | phosphoglucomutase 3 | 0.0185558 |
| STAG2 | stromal antigen 2 | 0.0184489 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0182699 |
| SVIL | supervillin | 0.018264 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0182384 |
| INHBA | inhibin, beta A | 0.0181983 |
| MMP12 | matrix metallopeptidase 12 | 0.018164 |
| GPHN | gephyrin | 0.0181245 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0181236 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0179884 |
| BRD2 | bromodomain containing 2 | 0.0177304 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0176775 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0173943 |
| EVC | Ellis van Creveld protein | 0.0172271 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0170917 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.171939 |
| FRMD4A | FERM domain containing 4A | -0.149413 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.1449 |
| FN1 | fibronectin 1 | -0.129184 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.1274 |
| TMSB10 | thymosin beta 10 | -0.122064 |
| HLA-B | major histocompatibility complex, class I, B | -0.103622 |
| FTL | ferritin, light polypeptide | -0.0817972 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0752232 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0741006 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0681225 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0668911 |
| PTMA | prothymosin, alpha | -0.0668237 |
| PGK1 | phosphoglycerate kinase 1 | -0.0650898 |
| IER3 | immediate early response 3 | -0.0600505 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0572508 |
| COL1A1 | collagen, type I, alpha 1 | -0.0560689 |
| RPS6 | ribosomal protein S6 | -0.0483674 |
| MT2A | metallothionein 2A | -0.0479421 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0477686 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0475086 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0436924 |
| RTN4 | reticulon 4 | -0.0425557 |
| COL1A2 | collagen, type I, alpha 2 | -0.042444 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0422552 |
| GLIS3 | GLIS family zinc finger 3 | -0.0422148 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0419202 |
| RPL35A | ribosomal protein L35a | -0.0419106 |
| GNAS | GNAS complex locus | -0.0398268 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0393419 |
| HLA-A | major histocompatibility complex, class I, A | -0.0392911 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0364934 |
| TPM4 | tropomyosin 4 | -0.0361351 |
| RPLP2 | ribosomal protein, large, P2 | -0.0358061 |
| RPS24 | ribosomal protein S24 | -0.0353306 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0350043 |
| CADM1 | cell adhesion molecule 1 | -0.0342995 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0341924 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0337477 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0337439 |
| EGR1 | early growth response 1 | -0.0336693 |
| RPS8 | ribosomal protein S8 | -0.0333238 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.032769 |
| RPL19 | ribosomal protein L19 | -0.0324427 |
| THBS1 | thrombospondin 1 | -0.0322892 |
| RPL36A | ribosomal protein L36a | -0.0319709 |
| TENM2 | teneurin transmembrane protein 2 | -0.0311716 |
| RPLP1 | ribosomal protein, large, P1 | -0.0306574 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0305017 |
| MKI67 | marker of proliferation Ki-67 | -0.0303628 |
| NDRG1 | N-myc downstream regulated 1 | -0.0303023 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0301661 |
| AHNAK | AHNAK nucleoprotein | -0.0301081 |
| RRBP1 | ribosome binding protein 1 | -0.0296617 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0292716 |
| RPL11 | ribosomal protein L11 | -0.0283174 |
| RPS19 | ribosomal protein S19 | -0.0282189 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0280063 |
| ANLN | anillin, actin binding protein | -0.0274918 |
| RPL32 | ribosomal protein L32 | -0.0274061 |
| RPS23 | ribosomal protein S23 | -0.0268255 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0267433 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.026173 |
| TXNRD1 | thioredoxin reductase 1 | -0.0258925 |
| RPL36 | ribosomal protein L36 | -0.0258249 |
| RPL37A | ribosomal protein L37a | -0.0255836 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0254604 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0252288 |
| HLA-E | major histocompatibility complex, class I, E | -0.0249805 |
| LRRC7 | leucine rich repeat containing 7 | -0.0246883 |
| LOX | lysyl oxidase | -0.0244394 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0244171 |
| TNNC1 | troponin C type 1 (slow) | -0.0243632 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0241653 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0240704 |
| RPL12 | ribosomal protein L12 | -0.0239852 |
| RPS21 | ribosomal protein S21 | -0.0237666 |
| FLNB | filamin B, beta | -0.0233276 |
| RPL26 | ribosomal protein L26 | -0.0233106 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0232814 |
| RPL9 | ribosomal protein L9 | -0.0232351 |
| DEK | DEK proto-oncogene | -0.0230902 |
| TUBB | tubulin, beta class I | -0.0230677 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0229858 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0228636 |
| NRN1 | neuritin 1 | -0.0227009 |
| KRT19 | keratin 19, type I | -0.0226569 |
| RPS13 | ribosomal protein S13 | -0.0226003 |
| RPS27A | ribosomal protein S27a | -0.0222479 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0220112 |
| PDE10A | phosphodiesterase 10A | -0.0218061 |
| RPL31 | ribosomal protein L31 | -0.0217516 |
| CENPF | centromere protein F, 350/400kDa | -0.0217126 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0216193 |
| CAVIN1 | caveolae associated protein 1 | -0.0214858 |
| ADM | adrenomedullin | -0.0214351 |
| RPS29 | ribosomal protein S29 | -0.021263 |
| CTSD | cathepsin D | -0.0208901 |
| RBM39 | RNA binding motif protein 39 | -0.0206146 |
| SRGN | serglycin | -0.0205527 |
