| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 4EGI-1 perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 4EGI-1_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NRXN3 | neurexin 3 | 0.117376 |
| CD44 | CD44 molecule (Indian blood group) | 0.0804979 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0695637 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0658208 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0640238 |
| VEGFA | vascular endothelial growth factor A | 0.0574672 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0570094 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0563674 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0550189 |
| KYNU | kynureninase | 0.0550076 |
| PRELID2 | PRELI domain containing 2 | 0.0549686 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0506825 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0490074 |
| HMGA2 | high mobility group AT-hook 2 | 0.0471989 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0468662 |
| FN1 | fibronectin 1 | 0.04466 |
| EGFR | epidermal growth factor receptor | 0.0425852 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0425562 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0424373 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0420379 |
| TNS3 | tensin 3 | 0.0390551 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0387868 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.038642 |
| VEGFC | vascular endothelial growth factor C | 0.0385532 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0375772 |
| HDAC9 | histone deacetylase 9 | 0.0372388 |
| FNIP1 | folliculin interacting protein 1 | 0.0359389 |
| EXOC4 | exocyst complex component 4 | 0.0353707 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0351254 |
| ATXN1 | ataxin 1 | 0.0350702 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0350341 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0350199 |
| DNAH11 | dynein, axonemal, heavy chain 11 | 0.0345994 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0335781 |
| AUTS2 | autism susceptibility candidate 2 | 0.0332664 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0328476 |
| GOLGB1 | golgin B1 | 0.0325162 |
| VCL | vinculin | 0.0324428 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0313045 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0312856 |
| SMYD3 | SET and MYND domain containing 3 | 0.0306172 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0298304 |
| PDLIM5 | PDZ and LIM domain 5 | 0.029595 |
| IL6ST | interleukin 6 signal transducer | 0.029037 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0287125 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.0282891 |
| FHIT | fragile histidine triad | 0.0282407 |
| HPCAL1 | hippocalcin-like 1 | 0.0276961 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0269746 |
| FAM20C | family with sequence similarity 20, member C | 0.0269277 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0268213 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0264068 |
| SCFD1 | sec1 family domain containing 1 | 0.0259252 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0256599 |
| EXOC6B | exocyst complex component 6B | 0.025531 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0254886 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0252921 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0250778 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0248755 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0248677 |
| UBC | ubiquitin C | 0.0243877 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0243505 |
| HIP1 | huntingtin interacting protein 1 | 0.024193 |
| MSN | moesin | 0.024096 |
| ZNF638 | zinc finger protein 638 | 0.0239526 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0239334 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0239067 |
| SETX | senataxin | 0.023631 |
| MYO9A | myosin IXA | 0.0235364 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0235232 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0234795 |
| SETBP1 | SET binding protein 1 | 0.0232703 |
| MMP12 | matrix metallopeptidase 12 | 0.0232481 |
| CALR | calreticulin | 0.0231012 |
| USO1 | USO1 vesicle transport factor | 0.0230762 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0230689 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0230652 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0230493 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.023003 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0229446 |
| ALK | anaplastic lymphoma receptor tyrosine kinase | 0.0228258 |
| COL5A1 | collagen, type V, alpha 1 | 0.0222477 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0221909 |
| FLNA | filamin A, alpha | 0.022133 |
| LAMB1 | laminin, beta 1 | 0.0220833 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0220566 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0219256 |
| MCL1 | myeloid cell leukemia 1 | 0.021836 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.021518 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0214207 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0213994 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0213947 |
| ECE1 | endothelin converting enzyme 1 | 0.021245 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.021229 |
| CDH13 | cadherin 13 | 0.0211757 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0209412 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.020805 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0207667 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0206504 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0206387 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.161064 |
| TMSB10 | thymosin beta 10 | -0.155111 |
| MT2A | metallothionein 2A | -0.14665 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.119623 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.107699 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0958271 |
| COL1A1 | collagen, type I, alpha 1 | -0.091204 |
| PTMA | prothymosin, alpha | -0.0876613 |
| COL1A2 | collagen, type I, alpha 2 | -0.0706029 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.069881 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0697007 |
| FTL | ferritin, light polypeptide | -0.0686536 |
| MT1X | metallothionein 1X | -0.0638562 |
| HLA-C | major histocompatibility complex, class I, C | -0.0596418 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0563757 |
| PRSS23 | protease, serine, 23 | -0.054661 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0515994 |
| OGA | O-GlcNAcase | -0.049969 |
| LOXL2 | lysyl oxidase-like 2 | -0.0492188 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.047306 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0462825 |
| HLA-A | major histocompatibility complex, class I, A | -0.046048 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0450015 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.043988 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0437119 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0433109 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.0431395 |
| CALU | calumenin | -0.0430268 |
| CAVIN1 | caveolae associated protein 1 | -0.0419978 |
| RRBP1 | ribosome binding protein 1 | -0.0403641 |
| HLA-B | major histocompatibility complex, class I, B | -0.0399764 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0396759 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0378527 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0365012 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0358187 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.034863 |
| RLF | rearranged L-myc fusion | -0.0344444 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0337 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0336242 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0334117 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0324333 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0323184 |
| TPX2 | TPX2, microtubule-associated | -0.0321374 |
| HMGB2 | high mobility group box 2 | -0.032021 |
| ADM | adrenomedullin | -0.0315391 |
| RTN4 | reticulon 4 | -0.0315276 |
| TFG | TRK-fused gene | -0.0312543 |
| ANLN | anillin, actin binding protein | -0.0305099 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.030415 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0303648 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0303451 |
| S100A10 | S100 calcium binding protein A10 | -0.030191 |
| RBM39 | RNA binding motif protein 39 | -0.0298992 |
| RPLP1 | ribosomal protein, large, P1 | -0.0293913 |
| RHEB | Ras homolog enriched in brain | -0.0287505 |
| ZNF292 | zinc finger protein 292 | -0.0282578 |
| LOX | lysyl oxidase | -0.0278689 |
| S100A9 | S100 calcium binding protein A9 | -0.0278224 |
| SEPTIN7 | septin 7 | -0.0274104 |
| HM13 | histocompatibility (minor) 13 | -0.0273088 |
| CANX | calnexin | -0.0271833 |
| COL5A2 | collagen, type V, alpha 2 | -0.0271473 |
| ARF1 | ADP-ribosylation factor 1 | -0.0271453 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0269862 |
| THY1 | Thy-1 cell surface antigen | -0.0267129 |
| HMGB1 | high mobility group box 1 | -0.0264092 |
| RPL34 | ribosomal protein L34 | -0.0259288 |
| SRGN | serglycin | -0.0258661 |
| YBX3 | Y box binding protein 3 | -0.0255369 |
| TPM2 | tropomyosin 2 (beta) | -0.0255194 |
| SRP54 | signal recognition particle 54kDa | -0.0252094 |
| GNAS | GNAS complex locus | -0.0251083 |
| MAP1B | microtubule-associated protein 1B | -0.0250915 |
| H3-3B | H3.3 histone B | -0.0250462 |
| RPL28 | ribosomal protein L28 | -0.0248249 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0247306 |
| INHBA | inhibin, beta A | -0.0247145 |
| PTN | pleiotrophin | -0.0245404 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0244719 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0243262 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0243045 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0238803 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0236117 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0235415 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0233452 |
| NOP58 | NOP58 ribonucleoprotein | -0.023144 |
| PTGES2 | prostaglandin E synthase 2 | -0.0230096 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0230022 |
| TMEM41B | transmembrane protein 41B | -0.0229634 |
| S100A6 | S100 calcium binding protein A6 | -0.0227902 |
| RPL8 | ribosomal protein L8 | -0.0226993 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.022625 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0225118 |
| CD99 | CD99 molecule | -0.0224627 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0224441 |
| SDC4 | syndecan 4 | -0.0223319 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0221629 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0217546 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.02159 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0215477 |
