| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 4EGI-1 perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 4EGI-1_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HMGA2 | high mobility group AT-hook 2 | 0.125183 |
| FMNL2 | formin-like 2 | 0.122295 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0983254 |
| SMYD3 | SET and MYND domain containing 3 | 0.0690961 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0651522 |
| CD44 | CD44 molecule (Indian blood group) | 0.0647991 |
| INTS6 | integrator complex subunit 6 | 0.0614328 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0541393 |
| SQSTM1 | sequestosome 1 | 0.0539446 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0539097 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0520726 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0502204 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0484159 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0434048 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0414789 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0387938 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0376176 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0357176 |
| PRR16 | proline rich 16 | 0.0352608 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0349225 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0324408 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0323959 |
| FNDC3B | fibronectin type III domain containing 3B | 0.032012 |
| HPCAL1 | hippocalcin-like 1 | 0.0318547 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0318251 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0314796 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.031329 |
| WWOX | WW domain containing oxidoreductase | 0.0297775 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.029141 |
| RPS3 | ribosomal protein S3 | 0.0284185 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0283127 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0278884 |
| ATM | ATM serine/threonine kinase | 0.0267104 |
| BPTF | bromodomain PHD finger transcription factor | 0.0266818 |
| SIK2 | salt-inducible kinase 2 | 0.0266018 |
| ASPH | aspartate beta-hydroxylase | 0.0262637 |
| GPHN | gephyrin | 0.0262497 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0262361 |
| SMAD3 | SMAD family member 3 | 0.0262035 |
| TLE4 | transducin-like enhancer of split 4 | 0.0261746 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0257215 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0255956 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0254977 |
| RAD51B | RAD51 paralog B | 0.0254084 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.025113 |
| NTN4 | netrin 4 | 0.0250177 |
| NABP1 | nucleic acid binding protein 1 | 0.024702 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0245459 |
| CNKSR3 | CNKSR family member 3 | 0.0244435 |
| SVIL | supervillin | 0.0243117 |
| NAV2 | neuron navigator 2 | 0.0242987 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0237212 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0236837 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0235396 |
| GPC6 | glypican 6 | 0.0232946 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0232111 |
| TUT7 | terminal uridylyl transferase 7 | 0.0228908 |
| GOLGA1 | golgin A1 | 0.022852 |
| SCAPER | S-phase cyclin A-associated protein in the ER | 0.0225377 |
| EXOC4 | exocyst complex component 4 | 0.0221853 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0218348 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 | 0.0217907 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0217189 |
| SPAG16 | sperm associated antigen 16 | 0.0215295 |
| RCOR1 | REST corepressor 1 | 0.0214269 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | 0.0212684 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0212475 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0212449 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0209861 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0209476 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0208508 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0208236 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0207415 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0206674 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | 0.020627 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0206075 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0206006 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0205632 |
| GATAD2A | GATA zinc finger domain containing 2A | 0.0203903 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.020352 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0202202 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0200804 |
| FMN1 | formin 1 | 0.0200489 |
| GPR39 | G protein-coupled receptor 39 | 0.0200102 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0198634 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0197518 |
| PHF3 | PHD finger protein 3 | 0.0197077 |
| TRIP11 | thyroid hormone receptor interactor 11 | 0.0196913 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | 0.0195196 |
| NBEA | neurobeachin | 0.0193731 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0192911 |
| KLHL29 | kelch-like family member 29 | 0.0192613 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0192591 |
| WDR70 | WD repeat domain 70 | 0.0191994 |
| LYRM4 | LYR motif containing 4 | 0.0191275 |
| HSPA8 | heat shock 70kDa protein 8 | 0.019099 |
| SKIL | SKI-like proto-oncogene | 0.0190628 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0187803 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0187461 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0185567 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.302316 |
| TMSB10 | thymosin beta 10 | -0.119412 |
| PTMA | prothymosin, alpha | -0.0867347 |
| MT2A | metallothionein 2A | -0.0722412 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0714991 |
| VIM | vimentin | -0.0709982 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0651319 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0630782 |
| RBM39 | RNA binding motif protein 39 | -0.0621492 |
| YBX3 | Y box binding protein 3 | -0.0524753 |
| SETD5 | SET domain containing 5 | -0.0489161 |
| CALU | calumenin | -0.0434583 |
| UBC | ubiquitin C | -0.0429742 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.042522 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0421382 |
| ANKRD37 | ankyrin repeat domain 37 | -0.0418069 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0408069 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0405126 |
| ERBIN | erbb2 interacting protein | -0.0401532 |
| HM13 | histocompatibility (minor) 13 | -0.0390236 |
| SNX14 | sorting nexin 14 | -0.0386119 |
| S100A9 | S100 calcium binding protein A9 | -0.0381861 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0373604 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0370898 |
| NUP58 | nucleoporin 58 | -0.0366225 |
| SEC24A | SEC24 family member A | -0.035814 |
| POTEF | POTE ankyrin domain family, member F | -0.0352546 |
| FLNB | filamin B, beta | -0.0350301 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0350134 |
| PKM | pyruvate kinase, muscle | -0.0342886 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0334387 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0334143 |
| PFN1 | profilin 1 | -0.0333194 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0330217 |
| SEPTIN7 | septin 7 | -0.0328995 |
| SPAG9 | sperm associated antigen 9 | -0.0327803 |
| GOLGA4 | golgin A4 | -0.0321212 |
| WDR45B | WD repeat domain 45B | -0.0320929 |
| ANXA2 | annexin A2 | -0.0319059 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0318322 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0318218 |
| ZNF292 | zinc finger protein 292 | -0.0316668 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0316201 |
| S100A10 | S100 calcium binding protein A10 | -0.0315244 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0304883 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0302797 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0301812 |
| RPL27A | ribosomal protein L27a | -0.0299664 |
| RPS27A | ribosomal protein S27a | -0.0296041 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0295677 |
| ANLN | anillin, actin binding protein | -0.0290726 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0290168 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0285337 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0283203 |
| MAP1B | microtubule-associated protein 1B | -0.0281323 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.027813 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0278059 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0276373 |
| PHIP | pleckstrin homology domain interacting protein | -0.0272492 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0271467 |
| CFDP1 | craniofacial development protein 1 | -0.0271168 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0270592 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0270157 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0268294 |
| TENT2 | terminal nucleotidyltransferase 2 | -0.0266093 |
| MSN | moesin | -0.0264837 |
| RPS13 | ribosomal protein S13 | -0.0263816 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0262679 |
| TPX2 | TPX2, microtubule-associated | -0.0260314 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0258121 |
| NKTR | natural killer cell triggering receptor | -0.0256209 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0255636 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.025532 |
| RRBP1 | ribosome binding protein 1 | -0.0254076 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.0252168 |
| GNAS | GNAS complex locus | -0.0251939 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.024901 |
| FAM13B | family with sequence similarity 13, member B | -0.0248642 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0248635 |
| JUN | jun proto-oncogene | -0.0246697 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0246208 |
| IKBIP | IKBKB interacting protein | -0.0246049 |
| MSANTD3 | Myb/SANT-like DNA-binding domain containing 3 | -0.0246014 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0245817 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0245347 |
| AHNAK | AHNAK nucleoprotein | -0.0245079 |
| NDRG1 | N-myc downstream regulated 1 | -0.0244238 |
| DIAPH3 | diaphanous-related formin 3 | -0.024245 |
| LDHA | lactate dehydrogenase A | -0.0242018 |
| FAM13A | family with sequence similarity 13, member A | -0.0238025 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0237411 |
| OXSR1 | oxidative stress responsive 1 | -0.0232946 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.023216 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0229298 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | -0.0229225 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0228827 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0227357 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0226995 |
| RBM25 | RNA binding motif protein 25 | -0.0224096 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0223721 |
