| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 4EGI-1 perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 4EGI-1_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.214637 |
| ITGA1 | integrin, alpha 1 | 0.095989 |
| SQSTM1 | sequestosome 1 | 0.0806294 |
| HMGA2 | high mobility group AT-hook 2 | 0.0752597 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0748524 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0743875 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0611413 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0598924 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0569112 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0527767 |
| VIM | vimentin | 0.0525071 |
| ASPH | aspartate beta-hydroxylase | 0.051901 |
| CTSB | cathepsin B | 0.0500428 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0465 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0462142 |
| FTL | ferritin, light polypeptide | 0.0454833 |
| CALR | calreticulin | 0.0445446 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0443926 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0439923 |
| NTN4 | netrin 4 | 0.0429552 |
| RPS8 | ribosomal protein S8 | 0.0426384 |
| SFTPA2 | surfactant protein A2 | 0.0408559 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0406577 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0405568 |
| RPL31 | ribosomal protein L31 | 0.0393434 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.037447 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0369122 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0368307 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0358109 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0357923 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0355773 |
| RPS27 | ribosomal protein S27 | 0.035345 |
| EMP1 | epithelial membrane protein 1 | 0.03508 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0346573 |
| TMEM156 | transmembrane protein 156 | 0.0342983 |
| ENO1 | enolase 1, (alpha) | 0.0340471 |
| RPL23 | ribosomal protein L23 | 0.0334604 |
| VEGFA | vascular endothelial growth factor A | 0.0332693 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0318919 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0318333 |
| RAI14 | retinoic acid induced 14 | 0.0317026 |
| RACK1 | receptor for activated C kinase 1 | 0.0308174 |
| SVIL | supervillin | 0.030368 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0302476 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0300164 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0297552 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0297016 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0296614 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.029615 |
| B2M | beta-2-microglobulin | 0.0288677 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0280905 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0276697 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.027504 |
| GPC6 | glypican 6 | 0.0273093 |
| ATF3 | activating transcription factor 3 | 0.0272741 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0268186 |
| MYO10 | myosin X | 0.026734 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0261778 |
| RASAL2 | RAS protein activator like 2 | 0.0260034 |
| ANXA5 | annexin A5 | 0.0259896 |
| SGMS2 | sphingomyelin synthase 2 | 0.0254479 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0251515 |
| FAT1 | FAT atypical cadherin 1 | 0.0251176 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0251073 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0250809 |
| VCAN | versican | 0.0248204 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0248021 |
| STC1 | stanniocalcin 1 | 0.0243665 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0241307 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0236698 |
| RPL13A | ribosomal protein L13a | 0.0235261 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0235015 |
| FAM13A | family with sequence similarity 13, member A | 0.0234654 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0228439 |
| FMNL2 | formin-like 2 | 0.0225983 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0223997 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0223927 |
| UBC | ubiquitin C | 0.0222679 |
| RPL35A | ribosomal protein L35a | 0.0220098 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.021569 |
| MLF1 | myeloid leukemia factor 1 | 0.0210091 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0205187 |
| UBL3 | ubiquitin-like 3 | 0.0205027 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0204993 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0202229 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.020199 |
| CD109 | CD109 molecule | 0.0199298 |
| LMAN2 | lectin, mannose-binding 2 | 0.0196401 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0195142 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.019478 |
| EZR | ezrin | 0.0192632 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0192561 |
| RPL12 | ribosomal protein L12 | 0.0190539 |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 | 0.0190081 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | 0.0188726 |
| MOK | MOK protein kinase | 0.0186863 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0186231 |
| ZFAND5 | zinc finger, AN1-type domain 5 | 0.0185143 |
| RPL5 | ribosomal protein L5 | 0.0184845 |
| PKP2 | plakophilin 2 | 0.01846 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | -0.155689 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.142775 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.117702 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.1166 |
| NDRG1 | N-myc downstream regulated 1 | -0.115987 |
| FN1 | fibronectin 1 | -0.114126 |
| CENPF | centromere protein F, 350/400kDa | -0.107518 |
| AHR | aryl hydrocarbon receptor | -0.0882354 |
| VCL | vinculin | -0.0855904 |
| RBM39 | RNA binding motif protein 39 | -0.0772887 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0760138 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0705141 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0703204 |
| PTMA | prothymosin, alpha | -0.0693375 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0657872 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0635112 |
| MKI67 | marker of proliferation Ki-67 | -0.0625554 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0620791 |
| EFNA5 | ephrin-A5 | -0.0617716 |
| FRY | furry homolog (Drosophila) | -0.0614493 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0612182 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0584792 |
| GOLT1B | golgi transport 1B | -0.0582638 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0574568 |
| PKM | pyruvate kinase, muscle | -0.055818 |
| TMEM263 | transmembrane protein 263 | -0.0550896 |
| FNBP1 | formin binding protein 1 | -0.0540297 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0530688 |
| OGA | O-GlcNAcase | -0.0522287 |
| ZNF292 | zinc finger protein 292 | -0.0520661 |
| ETV6 | ets variant 6 | -0.0516842 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0516232 |
| TXNIP | thioredoxin interacting protein | -0.0512099 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0510658 |
| POTEF | POTE ankyrin domain family, member F | -0.0509303 |
| CANX | calnexin | -0.050915 |
| TMEM165 | transmembrane protein 165 | -0.0508886 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0492084 |
| S100A6 | S100 calcium binding protein A6 | -0.04856 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0484035 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0478248 |
| MAP1B | microtubule-associated protein 1B | -0.0477052 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0473279 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0470497 |
| MT2A | metallothionein 2A | -0.0468318 |
| ANLN | anillin, actin binding protein | -0.0462605 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0442653 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0442555 |
| DUSP5 | dual specificity phosphatase 5 | -0.0439243 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0435046 |
| RUNX2 | runt-related transcription factor 2 | -0.0431642 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | -0.0425815 |
| NEK7 | NIMA-related kinase 7 | -0.0424552 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0423965 |
| XPO1 | exportin 1 | -0.0408057 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0403143 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0399393 |
| CDC73 | cell division cycle 73 | -0.0397955 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.03972 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0396858 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0395559 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0392886 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0391707 |
| OSMR | oncostatin M receptor | -0.0390686 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0389835 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0385932 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.03851 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.037619 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0369115 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0368232 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0366881 |
| SRPK2 | SRSF protein kinase 2 | -0.0366027 |
| RUNX1 | runt-related transcription factor 1 | -0.0365116 |
| ETNK1 | ethanolamine kinase 1 | -0.0361924 |
| TMSB10 | thymosin beta 10 | -0.0355924 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.035516 |
| SYT1 | synaptotagmin I | -0.0352596 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0351833 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0349043 |
| HDGF | hepatoma-derived growth factor | -0.0345254 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0340573 |
| TENM4 | teneurin transmembrane protein 4 | -0.0337506 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.032958 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0324165 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0322233 |
| INSIG2 | insulin induced gene 2 | -0.0321211 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0321052 |
| PTK2 | protein tyrosine kinase 2 | -0.0320384 |
| WDR1 | WD repeat domain 1 | -0.0315764 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0312781 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.0311787 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0309756 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0307058 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0306936 |
| RRBP1 | ribosome binding protein 1 | -0.0306636 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0305229 |
| HPCAL1 | hippocalcin-like 1 | -0.0303127 |
| NKTR | natural killer cell triggering receptor | -0.0302538 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0302291 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0301982 |
