| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 4EGI-1 perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 4EGI-1_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0914841 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.084062 |
| ASPH | aspartate beta-hydroxylase | 0.0764176 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0576579 |
| INTS6 | integrator complex subunit 6 | 0.0565968 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0514207 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0490041 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0463779 |
| PLEC | plectin | 0.0446503 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0427934 |
| DST | dystonin | 0.039429 |
| NAV2 | neuron navigator 2 | 0.0383047 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0362383 |
| LAMA4 | laminin, alpha 4 | 0.0348736 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0343701 |
| SPATA13 | spermatogenesis associated 13 | 0.0341738 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.034036 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.033433 |
| EZR | ezrin | 0.0333558 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0325393 |
| KRT18 | keratin 18, type I | 0.0324754 |
| EGFR | epidermal growth factor receptor | 0.0315275 |
| VCL | vinculin | 0.031417 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0312326 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.030382 |
| FRMD5 | FERM domain containing 5 | 0.0284893 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0284592 |
| CTSB | cathepsin B | 0.0280826 |
| KRT8 | keratin 8, type II | 0.0279993 |
| YAP1 | Yes-associated protein 1 | 0.0266462 |
| ACTN1 | actinin, alpha 1 | 0.025859 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0256962 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0256498 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0252136 |
| RCOR1 | REST corepressor 1 | 0.0251614 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0248955 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.02387 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0232319 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0221605 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0219962 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0214681 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0214262 |
| CLSTN2 | calsyntenin 2 | 0.0214024 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0212203 |
| CD44 | CD44 molecule (Indian blood group) | 0.0207846 |
| EMP1 | epithelial membrane protein 1 | 0.0205548 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0204677 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0201458 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0200011 |
| MYO1E | myosin IE | 0.0197441 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0196203 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0195966 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0195942 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0195079 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.019484 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.019479 |
| DOCK9 | dedicator of cytokinesis 9 | 0.0193566 |
| HPCAL1 | hippocalcin-like 1 | 0.0193394 |
| CDHR3 | cadherin-related family member 3 | 0.019082 |
| ITGB4 | integrin, beta 4 | 0.0188574 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0186241 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0180375 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0179841 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0177522 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.01765 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0176473 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0175913 |
| MSN | moesin | 0.017131 |
| LMO7 | LIM domain 7 | 0.0171241 |
| SQSTM1 | sequestosome 1 | 0.0171191 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0168451 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0166361 |
| VMP1 | vacuole membrane protein 1 | 0.0166187 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0165467 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0165392 |
| SMAD3 | SMAD family member 3 | 0.0164071 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0163627 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0163575 |
| UBAP2 | ubiquitin associated protein 2 | 0.0163486 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0162782 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0162663 |
| UCHL3 | ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) | 0.0162215 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0161389 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0160917 |
| KCNH8 | potassium channel, voltage gated eag related subfamily H, member 8 | 0.0153885 |
| AFAP1L2 | actin filament associated protein 1-like 2 | 0.0153444 |
| FHIT | fragile histidine triad | 0.015322 |
| ATXN7L1 | ataxin 7-like 1 | 0.0153151 |
| EPHA4 | EPH receptor A4 | 0.0152355 |
| HOMER1 | homer scaffolding protein 1 | 0.0149669 |
| ABR | active BCR-related | 0.0149173 |
| EXOC4 | exocyst complex component 4 | 0.0149066 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0148665 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0148197 |
| RBP1 | retinol binding protein 1, cellular | 0.0147698 |
| RPS12 | ribosomal protein S12 | 0.0147167 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0146918 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0145342 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0144643 |
| FAT1 | FAT atypical cadherin 1 | 0.0143339 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.240364 |
| TMSB10 | thymosin beta 10 | -0.153861 |
| PTMA | prothymosin, alpha | -0.149825 |
| RPL35A | ribosomal protein L35a | -0.113978 |
| RPS6 | ribosomal protein S6 | -0.105951 |
| RPLP1 | ribosomal protein, large, P1 | -0.0952257 |
| PGK1 | phosphoglycerate kinase 1 | -0.0646003 |
| RPS19 | ribosomal protein S19 | -0.0582292 |
| RPLP2 | ribosomal protein, large, P2 | -0.0545167 |
| RPL11 | ribosomal protein L11 | -0.05424 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0540328 |
| RPL19 | ribosomal protein L19 | -0.0528148 |
| RPL23 | ribosomal protein L23 | -0.0524362 |
| RPS24 | ribosomal protein S24 | -0.0523418 |
| RPS21 | ribosomal protein S21 | -0.0516254 |
| DIAPH3 | diaphanous-related formin 3 | -0.0508928 |
| RPL32 | ribosomal protein L32 | -0.0492209 |
| MKI67 | marker of proliferation Ki-67 | -0.0484305 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0484247 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0480742 |
| RPS13 | ribosomal protein S13 | -0.0479182 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0477409 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0467731 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0461628 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0443799 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0440853 |
| RPLP0 | ribosomal protein, large, P0 | -0.0436168 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0430335 |
| THOC2 | THO complex 2 | -0.0426215 |
| OXR1 | oxidation resistance 1 | -0.0422501 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0422093 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0421514 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0420831 |
| ANLN | anillin, actin binding protein | -0.0404653 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0390392 |
| FTL | ferritin, light polypeptide | -0.038879 |
| MT2A | metallothionein 2A | -0.0387753 |
| RPL27A | ribosomal protein L27a | -0.0380542 |
| CENPF | centromere protein F, 350/400kDa | -0.03758 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0375422 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0374714 |
| RUNX1 | runt-related transcription factor 1 | -0.0371193 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0370978 |
| GNAS | GNAS complex locus | -0.0362365 |
| RBM39 | RNA binding motif protein 39 | -0.0361186 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0359987 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0352009 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0351897 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0350644 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0349135 |
| RPS27A | ribosomal protein S27a | -0.0347523 |
| HMGB1 | high mobility group box 1 | -0.0341737 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0341666 |
| RPS23 | ribosomal protein S23 | -0.0340717 |
| HMGB2 | high mobility group box 2 | -0.0340666 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0339819 |
| RPL26 | ribosomal protein L26 | -0.0339564 |
| PFN1 | profilin 1 | -0.0335431 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0334988 |
| RPL34 | ribosomal protein L34 | -0.0331883 |
| RPL12 | ribosomal protein L12 | -0.0326677 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0320629 |
| RPL8 | ribosomal protein L8 | -0.0317389 |
| TPI1 | triosephosphate isomerase 1 | -0.031547 |
| H3-3B | H3.3 histone B | -0.0305574 |
| RBM25 | RNA binding motif protein 25 | -0.0305141 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0305082 |
| RPS3 | ribosomal protein S3 | -0.030496 |
| RPS4X | ribosomal protein S4, X-linked | -0.0304709 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0302585 |
| CBX3 | chromobox homolog 3 | -0.0302462 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.030155 |
| RPL36A | ribosomal protein L36a | -0.0300298 |
| DEK | DEK proto-oncogene | -0.0295086 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0293975 |
| RPL5 | ribosomal protein L5 | -0.0292925 |
| RPS11 | ribosomal protein S11 | -0.0290086 |
| TUBA1B | tubulin, alpha 1b | -0.0289652 |
| TXNIP | thioredoxin interacting protein | -0.0288619 |
| RPL18 | ribosomal protein L18 | -0.028706 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0286324 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.028562 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0285467 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0282307 |
| MORF4L2 | mortality factor 4 like 2 | -0.0280519 |
| RPL35 | ribosomal protein L35 | -0.0277126 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0275423 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0274977 |
| RPL9 | ribosomal protein L9 | -0.027489 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0272597 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0270508 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0269073 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0268968 |
| RPL7 | ribosomal protein L7 | -0.0268616 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0268463 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -0.0267975 |
| RPS5 | ribosomal protein S5 | -0.0266835 |
| RPL37 | ribosomal protein L37 | -0.0266215 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.0264603 |
| RPS16 | ribosomal protein S16 | -0.0262332 |
