| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 4EGI-1 perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 4EGI-1_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.312034 |
| HMGA2 | high mobility group AT-hook 2 | 0.185401 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.155676 |
| INHBA | inhibin, beta A | 0.139147 |
| MMP1 | matrix metallopeptidase 1 | 0.126078 |
| CD44 | CD44 molecule (Indian blood group) | 0.112337 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.111025 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.102367 |
| ASPH | aspartate beta-hydroxylase | 0.101081 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.10022 |
| STC1 | stanniocalcin 1 | 0.0909193 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0856002 |
| MYO10 | myosin X | 0.0832595 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0812035 |
| FMNL2 | formin-like 2 | 0.0743249 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0741034 |
| GLIS3 | GLIS family zinc finger 3 | 0.0723465 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0694295 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.06916 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0671292 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.06705 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0660444 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0641086 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0621451 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | 0.0605898 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0597901 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0596942 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0589558 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0578421 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0570151 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0551085 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0547993 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0540105 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0526349 |
| B2M | beta-2-microglobulin | 0.0520501 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0500807 |
| VCL | vinculin | 0.050055 |
| EGFR | epidermal growth factor receptor | 0.0499689 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.0497823 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0489327 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0488546 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0486459 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0459989 |
| RASA2 | RAS p21 protein activator 2 | 0.045963 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0443234 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0439796 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0438694 |
| KIAA1549L | KIAA1549-like | 0.0412066 |
| MT2A | metallothionein 2A | 0.0408462 |
| SPAG9 | sperm associated antigen 9 | 0.0407727 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | 0.0401016 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0399101 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.039903 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0390824 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0386383 |
| TOP1 | topoisomerase (DNA) I | 0.038435 |
| NOTCH2 | notch 2 | 0.0383508 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.038341 |
| NAV1 | neuron navigator 1 | 0.0382223 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0379605 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0374426 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0374418 |
| PTK2 | protein tyrosine kinase 2 | 0.0373088 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.037014 |
| SNX9 | sorting nexin 9 | 0.0365892 |
| ACTG1 | actin gamma 1 | 0.035976 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0355743 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0349755 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0343279 |
| INTS6 | integrator complex subunit 6 | 0.0338425 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0329622 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0324433 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.032386 |
| ANXA5 | annexin A5 | 0.0322553 |
| RPS12 | ribosomal protein S12 | 0.0318906 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0311591 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0307108 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0303159 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.030083 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0297781 |
| COL6A2 | collagen, type VI, alpha 2 | 0.02966 |
| JAK1 | Janus kinase 1 | 0.0293152 |
| EFCAB13 | EF-hand calcium binding domain 13 | 0.0292042 |
| ENO1 | enolase 1, (alpha) | 0.029172 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0291641 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0289532 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0286364 |
| FRMD4A | FERM domain containing 4A | 0.0284765 |
| NAV2 | neuron navigator 2 | 0.0283181 |
| APP | amyloid beta (A4) precursor protein | 0.0282801 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0281526 |
| RNF145 | ring finger protein 145 | 0.0279544 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0274602 |
| GPHN | gephyrin | 0.0272838 |
| POTEF | POTE ankyrin domain family, member F | 0.0271105 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0270514 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0268943 |
| EGR1 | early growth response 1 | 0.0267077 |
| SQSTM1 | sequestosome 1 | 0.0265824 |
| RAD51B | RAD51 paralog B | 0.0262121 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.159482 |
| VIM | vimentin | -0.11677 |
| COL1A1 | collagen, type I, alpha 1 | -0.113126 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0975995 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0920379 |
| COL1A2 | collagen, type I, alpha 2 | -0.0809322 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.074743 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0544924 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0499922 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0491522 |
| FBN1 | fibrillin 1 | -0.0483868 |
| TMSB10 | thymosin beta 10 | -0.0403007 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0387153 |
| TMEM165 | transmembrane protein 165 | -0.0371409 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.0370551 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0365991 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0344505 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0336077 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0322126 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.032119 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0310084 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0302635 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0296766 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0289315 |
| S100A6 | S100 calcium binding protein A6 | -0.0286923 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0278405 |
| NBEAL1 | neurobeachin-like 1 | -0.0275863 |
| CALR | calreticulin | -0.0270619 |
| NDRG1 | N-myc downstream regulated 1 | -0.026839 |
| NGLY1 | N-glycanase 1 | -0.0268028 |
| PRSS23 | protease, serine, 23 | -0.0263588 |
| GOLGA4 | golgin A4 | -0.0259068 |
| RRBP1 | ribosome binding protein 1 | -0.0255937 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0255447 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0253122 |
| LOX | lysyl oxidase | -0.0250257 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0249341 |
| SEC24D | SEC24 family member D | -0.0246582 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0242966 |
| DST | dystonin | -0.0240781 |
| CALU | calumenin | -0.0240554 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0237094 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.0235922 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0235514 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0228257 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0223793 |
| SRP54 | signal recognition particle 54kDa | -0.0219132 |
| VEPH1 | ventricular zone expressed PH domain-containing 1 | -0.0206341 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0204802 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.02039 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0196845 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0196623 |
| CENPE | centromere protein E, 312kDa | -0.0196001 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0195794 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.019494 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0193756 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0191046 |
| CEP95 | centrosomal protein 95kDa | -0.0191001 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0189475 |
| COG6 | component of oligomeric golgi complex 6 | -0.0188947 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0188493 |
| ANKRD28 | ankyrin repeat domain 28 | -0.018533 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0185037 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0184659 |
| SCFD1 | sec1 family domain containing 1 | -0.0184438 |
| ARF4 | ADP-ribosylation factor 4 | -0.0181652 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0180804 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0180715 |
| NLRP1 | NLR family, pyrin domain containing 1 | -0.0175901 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | -0.0175015 |
| ZFHX3 | zinc finger homeobox 3 | -0.017429 |
| TBC1D23 | TBC1 domain family, member 23 | -0.0171955 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0168586 |
| TMF1 | TATA element modulatory factor 1 | -0.0166141 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0164667 |
| NKTR | natural killer cell triggering receptor | -0.0163886 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0163056 |
| RARS1 | arginyl-tRNA synthetase 1 | -0.0161784 |
| RAI1 | retinoic acid induced 1 | -0.0161721 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0161369 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0160791 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0159957 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.015764 |
| DIAPH3 | diaphanous-related formin 3 | -0.0155796 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0155638 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0155225 |
| TRPC4 | transient receptor potential cation channel, subfamily C, member 4 | -0.0155222 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0153448 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0153409 |
| TMEM263 | transmembrane protein 263 | -0.0152871 |
| GOLT1B | golgi transport 1B | -0.0152852 |
| HAS2 | hyaluronan synthase 2 | -0.0151202 |
| SGO2 | shugoshin 2 | -0.0150939 |
| APAF1 | apoptotic peptidase activating factor 1 | -0.0150909 |
| NF1 | neurofibromin 1 | -0.0150862 |
| GOLGA2 | golgin A2 | -0.0150468 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0149426 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.014767 |
| RNF150 | ring finger protein 150 | -0.0146689 |
| MAP1B | microtubule-associated protein 1B | -0.0146548 |
