| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 5-Azacytidine perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 5-Azacytidine_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.144406 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.134854 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.121088 |
| FBN1 | fibrillin 1 | 0.101961 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0689682 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0663797 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0641202 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0616747 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0579236 |
| ATP13A3 | ATPase type 13A3 | 0.0530281 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0495844 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0492845 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0465399 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0414199 |
| SEPTIN9 | septin 9 | 0.0405211 |
| GOLGA4 | golgin A4 | 0.0384689 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0380503 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0379946 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.036836 |
| COL3A1 | collagen, type III, alpha 1 | 0.0365461 |
| CALR | calreticulin | 0.0364437 |
| APP | amyloid beta (A4) precursor protein | 0.0361342 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0355749 |
| DST | dystonin | 0.0354015 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0350747 |
| OPTN | optineurin | 0.0346883 |
| CD109 | CD109 molecule | 0.034365 |
| LOX | lysyl oxidase | 0.0326152 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0323422 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0320645 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0318443 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0316907 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0314935 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0314811 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0309346 |
| INSIG2 | insulin induced gene 2 | 0.0309095 |
| SBF2 | SET binding factor 2 | 0.0304709 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0293648 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0292199 |
| COL1A2 | collagen, type I, alpha 2 | 0.0286987 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0286599 |
| COL5A2 | collagen, type V, alpha 2 | 0.0285745 |
| PKM | pyruvate kinase, muscle | 0.0282581 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0282248 |
| RNF145 | ring finger protein 145 | 0.0281333 |
| GPC6 | glypican 6 | 0.027918 |
| OGA | O-GlcNAcase | 0.0278959 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0278764 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0273897 |
| COPA | coatomer protein complex, subunit alpha | 0.0271893 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0271525 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0270761 |
| TPM3 | tropomyosin 3 | 0.0268404 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0261089 |
| FMNL2 | formin-like 2 | 0.0254523 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | 0.0250209 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0249209 |
| HELZ | helicase with zinc finger | 0.0246955 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0246644 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0246374 |
| SPAG9 | sperm associated antigen 9 | 0.0245397 |
| MMP12 | matrix metallopeptidase 12 | 0.0244547 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0244296 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0243745 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0242883 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.024139 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0240896 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.024012 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0239838 |
| ATP11B | ATPase, class VI, type 11B | 0.0239267 |
| FRMD5 | FERM domain containing 5 | 0.0238332 |
| ITSN2 | intersectin 2 | 0.0236829 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0234717 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.023468 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0234084 |
| ADM | adrenomedullin | 0.0232934 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0231628 |
| FNIP1 | folliculin interacting protein 1 | 0.0231254 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0229473 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0226738 |
| NGLY1 | N-glycanase 1 | 0.0226526 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0225138 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.022021 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0219924 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0218679 |
| YEATS2 | YEATS domain containing 2 | 0.0216757 |
| MSN | moesin | 0.0216663 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0213893 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0213855 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0211532 |
| DENND5A | DENN/MADD domain containing 5A | 0.0209622 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.0209345 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 0.0208785 |
| ARRDC3 | arrestin domain containing 3 | 0.0207612 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0206837 |
| LOXL2 | lysyl oxidase-like 2 | 0.0206733 |
| FNBP4 | formin binding protein 4 | 0.0206476 |
| HIP1 | huntingtin interacting protein 1 | 0.0205353 |
| UBC | ubiquitin C | 0.0202195 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0201941 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.216857 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.20526 |
| VIM | vimentin | -0.162175 |
| CDH13 | cadherin 13 | -0.132874 |
| AHNAK | AHNAK nucleoprotein | -0.130571 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.123498 |
| MT2A | metallothionein 2A | -0.120008 |
| S100A10 | S100 calcium binding protein A10 | -0.11879 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.112321 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.108872 |
| NAV1 | neuron navigator 1 | -0.0871487 |
| COL5A1 | collagen, type V, alpha 1 | -0.0870751 |
| HLA-B | major histocompatibility complex, class I, B | -0.0823795 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.081472 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0791372 |
| PLAT | plasminogen activator, tissue | -0.0763926 |
| MAP1B | microtubule-associated protein 1B | -0.0704295 |
| FN1 | fibronectin 1 | -0.064158 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0611263 |
| LMNA | lamin A/C | -0.0586548 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.054278 |
| EFNA5 | ephrin-A5 | -0.0541957 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0541263 |
| CSTB | cystatin B (stefin B) | -0.0503833 |
| NDRG1 | N-myc downstream regulated 1 | -0.0503006 |
| S100A6 | S100 calcium binding protein A6 | -0.0501072 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0498291 |
| HLA-C | major histocompatibility complex, class I, C | -0.0490832 |
| SLC39A11 | solute carrier family 39, member 11 | -0.048331 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0481556 |
| RIGI | RNA sensor RIG-I | -0.0472892 |
| CAVIN1 | caveolae associated protein 1 | -0.0454502 |
| MX2 | MX dynamin-like GTPase 2 | -0.0444102 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0441675 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0440675 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.044059 |
| ASPH | aspartate beta-hydroxylase | -0.0419691 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0406723 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0406302 |
| PRSS23 | protease, serine, 23 | -0.0396918 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0395194 |
| SUCNR1 | succinate receptor 1 | -0.0394949 |
| CCND1 | cyclin D1 | -0.039379 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0393251 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0386888 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0373932 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0372037 |
| SP100 | SP100 nuclear antigen | -0.0363054 |
| PLXNA2 | plexin A2 | -0.0362781 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0360306 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0359082 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0358636 |
| S100A4 | S100 calcium binding protein A4 | -0.0346915 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0342827 |
| PODXL | podocalyxin-like | -0.0340893 |
| CUX1 | cut-like homeobox 1 | -0.0338482 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0336643 |
| DGKG | diacylglycerol kinase, gamma 90kDa | -0.0332226 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.033026 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0327702 |
| RRBP1 | ribosome binding protein 1 | -0.0326306 |
| LRRC17 | leucine rich repeat containing 17 | -0.0325525 |
| PTMA | prothymosin, alpha | -0.0321808 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0317382 |
| SEPTIN7 | septin 7 | -0.0310584 |
| RPLP1 | ribosomal protein, large, P1 | -0.0305408 |
| RPS24 | ribosomal protein S24 | -0.0304274 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0301005 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0297356 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0295993 |
| CD99 | CD99 molecule | -0.029451 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0288214 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0287114 |
| RPL28 | ribosomal protein L28 | -0.0287025 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.0286642 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0281809 |
| RPL23 | ribosomal protein L23 | -0.0281589 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0279898 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0279388 |
| RPL35A | ribosomal protein L35a | -0.0278534 |
| RPS15 | ribosomal protein S15 | -0.0277026 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0273011 |
| SEC61G | Sec61 gamma subunit | -0.027288 |
| EGFR | epidermal growth factor receptor | -0.0271467 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0271357 |
| CYTH3 | cytohesin 3 | -0.0268553 |
| ACTG1 | actin gamma 1 | -0.0268505 |
| DCLK2 | doublecortin-like kinase 2 | -0.026794 |
| CDK6 | cyclin-dependent kinase 6 | -0.0261232 |
| IL7R | interleukin 7 receptor | -0.0257991 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0256686 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0256532 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0255783 |
| RPS19 | ribosomal protein S19 | -0.0254845 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0253032 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0251536 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.024956 |
| ANXA2 | annexin A2 | -0.0247506 |
| RPS8 | ribosomal protein S8 | -0.0241714 |
| PGK1 | phosphoglycerate kinase 1 | -0.0241032 |
