| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 5-Azacytidine perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 5-Azacytidine_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | 0.111229 |
| ANXA1 | annexin A1 | 0.107917 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.101199 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0995156 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0673039 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.06287 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.056555 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0497678 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0492083 |
| KIF5B | kinesin family member 5B | 0.047538 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0461617 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0448283 |
| ECT2 | epithelial cell transforming 2 | 0.0435495 |
| TPM3 | tropomyosin 3 | 0.0420991 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0385101 |
| CEP192 | centrosomal protein 192kDa | 0.0369595 |
| PLK2 | polo-like kinase 2 | 0.0364374 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0358824 |
| RPL41 | ribosomal protein L41 | 0.0350505 |
| CLDND1 | claudin domain containing 1 | 0.0350043 |
| CCNL1 | cyclin L1 | 0.0349532 |
| TPR | translocated promoter region, nuclear basket protein | 0.0334619 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0333139 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0331369 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0323233 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0322023 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.031695 |
| TMEM41B | transmembrane protein 41B | 0.0314958 |
| CENPE | centromere protein E, 312kDa | 0.0304024 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.030376 |
| GASK1B | golgi associated kinase 1B | 0.0293314 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0287005 |
| ZNF146 | zinc finger protein 146 | 0.027947 |
| DSPP | dentin sialophosphoprotein | 0.0272764 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.027207 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0270424 |
| PCBP2 | poly(rC) binding protein 2 | 0.0269866 |
| CEP70 | centrosomal protein 70kDa | 0.0267751 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0266989 |
| ENO1 | enolase 1, (alpha) | 0.0264889 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0262977 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0262614 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0262556 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0260439 |
| MKI67 | marker of proliferation Ki-67 | 0.0259733 |
| RPL4 | ribosomal protein L4 | 0.0255465 |
| HDAC9 | histone deacetylase 9 | 0.0255346 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0254081 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0248874 |
| NUP58 | nucleoporin 58 | 0.024804 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0240878 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0240563 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0239789 |
| GPR15 | G protein-coupled receptor 15 | 0.0237216 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0235759 |
| EZR | ezrin | 0.0233119 |
| YTHDC1 | YTH domain containing 1 | 0.0227876 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0226222 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0224074 |
| LEMD3 | LEM domain containing 3 | 0.0223855 |
| LMO7 | LIM domain 7 | 0.0223581 |
| NDC80 | NDC80 kinetochore complex component | 0.0222715 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0219482 |
| AHR | aryl hydrocarbon receptor | 0.0217737 |
| CLDN1 | claudin 1 | 0.0217264 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.0214916 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0212927 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0207893 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0207189 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0206053 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0205268 |
| EDN1 | endothelin 1 | 0.0200742 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0197528 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0197322 |
| AFDN | afadin, adherens junction formation factor | 0.019698 |
| CPNE1 | copine I | 0.0195886 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0195169 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0192745 |
| KIF1B | kinesin family member 1B | 0.0192705 |
| CENPF | centromere protein F, 350/400kDa | 0.0190952 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0190591 |
| CPSF6 | cleavage and polyadenylation specific factor 6, 68kDa | 0.019045 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0190159 |
| IPMK | inositol polyphosphate multikinase | 0.018818 |
| ZBTB11 | zinc finger and BTB domain containing 11 | 0.0187029 |
| CLTC | clathrin, heavy chain (Hc) | 0.0185911 |
| CBX5 | chromobox homolog 5 | 0.0183546 |
| SSR1 | signal sequence receptor, alpha | 0.0182951 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0182667 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0178696 |
| MYPN | myopalladin | 0.0178464 |
| TARDBP | TAR DNA binding protein | 0.0177988 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0175821 |
| YEATS2 | YEATS domain containing 2 | 0.0174848 |
| CASC3 | cancer susceptibility candidate 3 | 0.0174094 |
| PANK3 | pantothenate kinase 3 | 0.0173102 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0172566 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | 0.0172458 |
| ITSN2 | intersectin 2 | 0.0170909 |
| OXR1 | oxidation resistance 1 | 0.0170542 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.298581 |
| TMSB10 | thymosin beta 10 | -0.146182 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.114216 |
| PTMA | prothymosin, alpha | -0.0922828 |
| VIM | vimentin | -0.0897472 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0831606 |
| NLGN1 | neuroligin 1 | -0.0826953 |
| FTL | ferritin, light polypeptide | -0.0816372 |
| HMGA1 | high mobility group AT-hook 1 | -0.0674644 |
| HMGA2 | high mobility group AT-hook 2 | -0.0668981 |
| RPL23 | ribosomal protein L23 | -0.0668129 |
| RPL35A | ribosomal protein L35a | -0.0657329 |
| ACTG1 | actin gamma 1 | -0.0649975 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0638657 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0595426 |
| RPS6 | ribosomal protein S6 | -0.0589136 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0570486 |
| RPLP1 | ribosomal protein, large, P1 | -0.0566474 |
| RPS27A | ribosomal protein S27a | -0.0549825 |
| AHNAK | AHNAK nucleoprotein | -0.0506127 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0499702 |
| RPS19 | ribosomal protein S19 | -0.0460745 |
| YAP1 | Yes-associated protein 1 | -0.0450181 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0442376 |
| RPL19 | ribosomal protein L19 | -0.0432629 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0403894 |
| RPL38 | ribosomal protein L38 | -0.0402187 |
| RPS8 | ribosomal protein S8 | -0.0401479 |
| RPS24 | ribosomal protein S24 | -0.0391028 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0381982 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0379002 |
| CCND1 | cyclin D1 | -0.0376154 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0366476 |
| HMGB1 | high mobility group box 1 | -0.0353077 |
| RPL34 | ribosomal protein L34 | -0.0349961 |
| ZNF804A | zinc finger protein 804A | -0.034785 |
| RPL12 | ribosomal protein L12 | -0.0347441 |
| RPL36 | ribosomal protein L36 | -0.0346124 |
| S100A10 | S100 calcium binding protein A10 | -0.0346008 |
| RPL9 | ribosomal protein L9 | -0.0339114 |
| EGR1 | early growth response 1 | -0.0335736 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0330831 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0323598 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0323542 |
| RPS21 | ribosomal protein S21 | -0.0321274 |
| CUX1 | cut-like homeobox 1 | -0.0313331 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0308294 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0307336 |
| MAP1B | microtubule-associated protein 1B | -0.0299731 |
| PFN1 | profilin 1 | -0.0298029 |
| GNAS | GNAS complex locus | -0.0294419 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0290989 |
| PARD3 | par-3 family cell polarity regulator | -0.0286731 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0285133 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0283826 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.028131 |
| RPLP2 | ribosomal protein, large, P2 | -0.0274937 |
| RPL37A | ribosomal protein L37a | -0.027279 |
| RPS15 | ribosomal protein S15 | -0.027192 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0268183 |
| TMEM123 | transmembrane protein 123 | -0.0267928 |
| H1-0 | H1.0 linker histone | -0.0265707 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0264848 |
| RPS5 | ribosomal protein S5 | -0.0264124 |
| TENM3 | teneurin transmembrane protein 3 | -0.0264096 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0261607 |
| RBM39 | RNA binding motif protein 39 | -0.0255804 |
| NHSL1 | NHS-like 1 | -0.0255745 |
| RPL31 | ribosomal protein L31 | -0.0254672 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0253309 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0252855 |
| RPS23 | ribosomal protein S23 | -0.025037 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.02463 |
| YBX1 | Y box binding protein 1 | -0.0244469 |
| BCHE | butyrylcholinesterase | -0.0242035 |
| RPL11 | ribosomal protein L11 | -0.0239208 |
| CANX | calnexin | -0.0237655 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0237568 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0235645 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.023555 |
| RPL26 | ribosomal protein L26 | -0.0234926 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0232656 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0232349 |
| ANXA2 | annexin A2 | -0.0229361 |
| S100A11 | S100 calcium binding protein A11 | -0.0228004 |
| EXOC4 | exocyst complex component 4 | -0.0225918 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0222142 |
| RPS27 | ribosomal protein S27 | -0.0217643 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0217429 |
| SETD5 | SET domain containing 5 | -0.0217104 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0216604 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0215541 |
| RPS29 | ribosomal protein S29 | -0.0214386 |
| TUBA1B | tubulin, alpha 1b | -0.0214149 |
| L3MBTL4 | l(3)mbt-like 4 (Drosophila) | -0.0213176 |
| PCDH9 | protocadherin 9 | -0.0213107 |
| RPLP0 | ribosomal protein, large, P0 | -0.0212499 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.021079 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0208931 |
| RPS16 | ribosomal protein S16 | -0.0208532 |
