5-Azacytidine_CHP-212 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description 5-Azacytidine perturbation in CHP-212 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the 5-Azacytidine_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
AKAP12 A kinase (PRKA) anchor protein 12 0.203155
EXT1 exostosin glycosyltransferase 1 0.0958593
FNDC3B fibronectin type III domain containing 3B 0.08745
FAM13A family with sequence similarity 13, member A 0.0854877
PLAT plasminogen activator, tissue 0.0698681
HELZ helicase with zinc finger 0.0610647
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0572006
NRG1 neuregulin 1 0.0551855
FMN1 formin 1 0.0509942
MSI2 musashi RNA-binding protein 2 0.050768
AFF4 AF4/FMR2 family, member 4 0.0490099
GPC5 glypican 5 0.0454744
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0444986
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0439463
VCL vinculin 0.0417868
COL3A1 collagen, type III, alpha 1 0.0410627
CEMIP cell migration inducing protein, hyaluronan binding 0.0410473
APP amyloid beta (A4) precursor protein 0.0409979
COPA coatomer protein complex, subunit alpha 0.0381291
KDM3A lysine (K)-specific demethylase 3A 0.0376146
VMP1 vacuole membrane protein 1 0.0369706
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 0.0362427
WAC WW domain containing adaptor with coiled-coil 0.0352704
DSCAM Down syndrome cell adhesion molecule 0.0351125
DDIT4 DNA-damage-inducible transcript 4 0.0341517
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 0.0337487
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 0.0331372
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 0.0326275
HMGB2 high mobility group box 2 0.0323579
PDE3A phosphodiesterase 3A, cGMP-inhibited 0.0315762
ENO1 enolase 1, (alpha) 0.0313909
CALR calreticulin 0.0312117
MYH9 myosin, heavy chain 9, non-muscle 0.0308658
TIMP3 TIMP metallopeptidase inhibitor 3 0.0307581
STARD4 StAR-related lipid transfer (START) domain containing 4 0.0302099
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0295965
UBE2O ubiquitin-conjugating enzyme E2O 0.0293649
PSD3 pleckstrin and Sec7 domain containing 3 0.0290862
NFE2L1 nuclear factor, erythroid 2-like 1 0.0290182
RPL41 ribosomal protein L41 0.0287787
IGF1R insulin-like growth factor 1 receptor 0.0287775
CSNK1G1 casein kinase 1, gamma 1 0.0286861
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.0282586
ZC3H11A zinc finger CCCH-type containing 11A 0.0278199
GARS1 glycyl-tRNA synthetase 1 0.0275919
EIF4B eukaryotic translation initiation factor 4B 0.0273911
WDR45B WD repeat domain 45B 0.0272491
NIPBL Nipped-B homolog (Drosophila) 0.0271687
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 0.0270225
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.0265822
DTNA dystrobrevin, alpha 0.0265172
CEP95 centrosomal protein 95kDa 0.02631
SRRM2 serine/arginine repetitive matrix 2 0.0262903
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0262854
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.0261043
SQSTM1 sequestosome 1 0.0259662
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0258342
CRH corticotropin releasing hormone 0.0258081
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0257378
TENT5A terminal nucleotidyltransferase 5A 0.0255019
USP9X ubiquitin specific peptidase 9, X-linked 0.0254552
NRIP1 nuclear receptor interacting protein 1 0.025434
KMT2C lysine (K)-specific methyltransferase 2C 0.0253772
CCNY cyclin Y 0.0253691
SEPTIN9 septin 9 0.0252646
AUTS2 autism susceptibility candidate 2 0.0250459
ACIN1 apoptotic chromatin condensation inducer 1 0.0250328
RAP1B RAP1B, member of RAS oncogene family 0.0249275
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.0247501
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 0.0247125
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.024674
TPR translocated promoter region, nuclear basket protein 0.0245888
AFDN afadin, adherens junction formation factor 0.0245588
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.0243253
FXR1 fragile X mental retardation, autosomal homolog 1 0.0243017
LIMCH1 LIM and calponin homology domains 1 0.0242872
KLF7 Kruppel-like factor 7 (ubiquitous) 0.0237198
RAD21 RAD21 homolog (S. pombe) 0.0236619
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.0234045
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 0.0233117
LPIN1 lipin 1 0.0230255
SEPTIN2 septin 2 0.0227299
THSD4 thrombospondin, type I, domain containing 4 0.0227152
SOX9 SRY (sex determining region Y)-box 9 0.0225092
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.0225074
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0224338
UBA2 ubiquitin-like modifier activating enzyme 2 0.0224026
ARID5B AT rich interactive domain 5B (MRF1-like) 0.0223589
PTK2 protein tyrosine kinase 2 0.0222878
CASC3 cancer susceptibility candidate 3 0.0219736
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 0.0219449
OGA O-GlcNAcase 0.0217684
GPBP1 GC-rich promoter binding protein 1 0.0217107
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0217095
TCERG1 transcription elongation regulator 1 0.0215343
BIRC2 baculoviral IAP repeat containing 2 0.0214822
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.0213449
BRD4 bromodomain containing 4 0.0211692
PHIP pleckstrin homology domain interacting protein 0.0210427
SEC31A SEC31 homolog A (S. cerevisiae) 0.0210402

decreased expression

Symbol Name Standardized Value
IGF2 insulin-like growth factor 2 -0.340704
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.309147
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 -0.13864
MEIS2 Meis homeobox 2 -0.10612
SYT1 synaptotagmin I -0.0822944
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0773535
B2M beta-2-microglobulin -0.0661972
RPS6 ribosomal protein S6 -0.0654988
BCAS3 breast carcinoma amplified sequence 3 -0.0616672
GATA3 GATA binding protein 3 -0.0593537
CDH10 cadherin 10, type 2 (T2-cadherin) -0.0572383
PCDH9 protocadherin 9 -0.0569768
VIM vimentin -0.055913
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0528449
PTPRD protein tyrosine phosphatase, receptor type, D -0.0523318
TMTC2 transmembrane and tetratricopeptide repeat containing 2 -0.0485795
RPL23 ribosomal protein L23 -0.048209
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.0459391
MAP1B microtubule-associated protein 1B -0.0448976
COL1A1 collagen, type I, alpha 1 -0.0441772
RPL19 ribosomal protein L19 -0.0436312
PLPP1 phospholipid phosphatase 1 -0.0432514
DPH6 diphthamine biosynthesis 6 -0.0429037
ACTG1 actin gamma 1 -0.0419538
BPTF bromodomain PHD finger transcription factor -0.0408162
RPS23 ribosomal protein S23 -0.039724
TRIB2 tribbles pseudokinase 2 -0.039443
RPS15 ribosomal protein S15 -0.0375359
IFI16 interferon, gamma-inducible protein 16 -0.0370267
RPL37A ribosomal protein L37a -0.0369917
RPL35A ribosomal protein L35a -0.0365694
TMSB10 thymosin beta 10 -0.0356419
RPLP1 ribosomal protein, large, P1 -0.0353899
RPS19 ribosomal protein S19 -0.0341546
PDE4D phosphodiesterase 4D, cAMP-specific -0.0330445
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 -0.031977
FNBP1 formin binding protein 1 -0.0314993
NRP1 neuropilin 1 -0.0307755
GLI3 GLI family zinc finger 3 -0.0302917
RPL13A ribosomal protein L13a -0.0291946
NFE2L2 nuclear factor, erythroid 2-like 2 -0.0284863
SVIL supervillin -0.0281644
PHOX2B paired-like homeobox 2b -0.027996
LSAMP limbic system-associated membrane protein -0.0279243
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.0279141
ADGRB3 adhesion G protein-coupled receptor B3 -0.027186
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) -0.0271345
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -0.0265965
RPLP2 ribosomal protein, large, P2 -0.0263403
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -0.0263065
TPT1 tumor protein, translationally-controlled 1 -0.0259821
HAND2 heart and neural crest derivatives expressed 2 -0.0258931
EIF5B eukaryotic translation initiation factor 5B -0.0251657
SCAF11 SR-related CTD-associated factor 11 -0.024844
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 -0.0247836
RPL38 ribosomal protein L38 -0.0247293
DEK DEK proto-oncogene -0.0244636
ATP5F1B ATP synthase F1 subunit beta -0.0243599
HAS2 hyaluronan synthase 2 -0.0242967
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0238954
RPS29 ribosomal protein S29 -0.0234438
ZNF652 zinc finger protein 652 -0.0229836
CD36 CD36 molecule (thrombospondin receptor) -0.0229775
RPS10 ribosomal protein S10 -0.0228137
PCNX2 pecanex 2 -0.0227953
LINGO2 leucine rich repeat and Ig domain containing 2 -0.0226876
RHOBTB3 Rho-related BTB domain containing 3 -0.0226067
FRMD4A FERM domain containing 4A -0.0225427
PRKCA protein kinase C, alpha -0.022519
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta -0.0224756
TTC17 tetratricopeptide repeat domain 17 -0.022353
PDZRN3 PDZ domain containing ring finger 3 -0.0222323
RPS5 ribosomal protein S5 -0.0221713
TIMP2 TIMP metallopeptidase inhibitor 2 -0.0221666
GLG1 golgi glycoprotein 1 -0.0220392
RPL21 ribosomal protein L21 -0.0218902
ZNFX1 zinc finger, NFX1-type containing 1 -0.0218549
SSR2 signal sequence receptor, beta (translocon-associated protein beta) -0.0215213
FN1 fibronectin 1 -0.0214666
RPL32 ribosomal protein L32 -0.0214426
MBD5 methyl-CpG binding domain protein 5 -0.0213194
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) -0.0212944
DLC1 DLC1 Rho GTPase activating protein -0.021294
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0212093
CADM2 cell adhesion molecule 2 -0.021201
RPL36 ribosomal protein L36 -0.0211605
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.0210372
PTEN phosphatase and tensin homolog -0.0210011
TLE4 transducin-like enhancer of split 4 -0.0209348
KTN1 kinectin 1 (kinesin receptor) -0.0209008
NEK1 NIMA-related kinase 1 -0.0206582
RUNX1 runt-related transcription factor 1 -0.0205749
DSTN destrin (actin depolymerizing factor) -0.0205526
KDM2A lysine (K)-specific demethylase 2A -0.020497
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) -0.0204385
EPHA6 EPH receptor A6 -0.0202719
CYB5R3 cytochrome b5 reductase 3 -0.0201312
STAT1 signal transducer and activator of transcription 1, 91kDa -0.0200005
EIF1 eukaryotic translation initiation factor 1 -0.0199836
RAB7A RAB7A, member RAS oncogene family -0.0198184