5-Azacytidine_COLO 205 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description 5-Azacytidine perturbation in COLO 205 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the 5-Azacytidine_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
LMO7 LIM domain 7 0.130211
MBNL2 muscleblind-like splicing regulator 2 0.121218
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 0.116867
SPTBN1 spectrin, beta, non-erythrocytic 1 0.108987
DSCAM Down syndrome cell adhesion molecule 0.0841278
INTS6 integrator complex subunit 6 0.0813663
TXNIP thioredoxin interacting protein 0.0794724
GOLGB1 golgin B1 0.0704135
FNDC3A fibronectin type III domain containing 3A 0.0671647
ERN1 endoplasmic reticulum to nucleus signaling 1 0.064
BTBD9 BTB (POZ) domain containing 9 0.0612972
SRRM2 serine/arginine repetitive matrix 2 0.0562309
JUN jun proto-oncogene 0.0548905
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 0.0541189
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0530209
VMP1 vacuole membrane protein 1 0.0529972
HKDC1 hexokinase domain containing 1 0.0527793
PKM pyruvate kinase, muscle 0.0516594
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.0516188
SMAD3 SMAD family member 3 0.0500123
ENO1 enolase 1, (alpha) 0.0475762
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 0.0451891
SLC38A2 solute carrier family 38, member 2 0.0418031
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0414983
CALR calreticulin 0.0410637
AKAP9 A kinase (PRKA) anchor protein 9 0.0391049
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 0.038262
GFPT1 glutamine--fructose-6-phosphate transaminase 1 0.0381563
KMT2C lysine (K)-specific methyltransferase 2C 0.0375296
BCLAF1 BCL2-associated transcription factor 1 0.0372324
DST dystonin 0.0370891
AFF4 AF4/FMR2 family, member 4 0.0368144
DSPP dentin sialophosphoprotein 0.0364178
PRRC2C proline-rich coiled-coil 2C 0.0353835
SLK STE20-like kinase 0.0353675
ZSWIM6 zinc finger, SWIM-type containing 6 0.035152
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.0350936
ERRFI1 ERBB receptor feedback inhibitor 1 0.0347249
EREG epiregulin 0.0319694
FOXO3 forkhead box O3 0.0319474
CPEB4 cytoplasmic polyadenylation element binding protein 4 0.0319461
CEMIP2 cell migration inducing hyaluronidase 2 0.0312117
CCNL1 cyclin L1 0.0312104
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0304965
LDHA lactate dehydrogenase A 0.0304623
GARS1 glycyl-tRNA synthetase 1 0.0285639
PDZD8 PDZ domain containing 8 0.0284119
LURAP1L leucine rich adaptor protein 1-like 0.028396
UBL3 ubiquitin-like 3 0.0282617
ZNF841 zinc finger protein 841 0.0275963
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease 0.0275745
SAMD4A sterile alpha motif domain containing 4A 0.027442
IARS1 isoleucyl-tRNA synthetase 1 0.0274165
TMED2 transmembrane emp24 domain trafficking protein 2 0.0272346
AREG amphiregulin 0.0266659
FTH1 ferritin, heavy polypeptide 1 0.02665
DDIT3 DNA-damage-inducible transcript 3 0.0262025
CANX calnexin 0.0261165
SEC24D SEC24 family member D 0.0259194
SEC31A SEC31 homolog A (S. cerevisiae) 0.0258852
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 0.025726
NEBL nebulette 0.02551
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 0.0249475
SPAG9 sperm associated antigen 9 0.0247707
HYOU1 hypoxia up-regulated 1 0.0236417
VEGFA vascular endothelial growth factor A 0.0235547
ASPH aspartate beta-hydroxylase 0.0231466
SON SON DNA binding protein 0.0231166
SEC23B Sec23 homolog B (S. cerevisiae) 0.0230046
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.0229558
ZNF638 zinc finger protein 638 0.0229082
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0228096
SSR1 signal sequence receptor, alpha 0.0225782
NCOA3 nuclear receptor coactivator 3 0.0224941
AARS1 alanyl-tRNA synthetase 1 0.0224668
TES testin LIM domain protein 0.0223863
USP53 ubiquitin specific peptidase 53 0.0222758
GOLGA4 golgin A4 0.022109
FNIP1 folliculin interacting protein 1 0.0220938
USP9X ubiquitin specific peptidase 9, X-linked 0.0220493
SRP54 signal recognition particle 54kDa 0.0216819
AP1G1 adaptor-related protein complex 1, gamma 1 subunit 0.0216165
TMF1 TATA element modulatory factor 1 0.021602
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.0214932
TRIP11 thyroid hormone receptor interactor 11 0.0214283
PJA2 praja ring finger 2, E3 ubiquitin protein ligase 0.0212233
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 0.0209525
B3GNT5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 0.0209055
XPOT exportin, tRNA 0.0208765
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.0207542
COPA coatomer protein complex, subunit alpha 0.0207273
USO1 USO1 vesicle transport factor 0.0206567
PIBF1 progesterone immunomodulatory binding factor 1 0.0206554
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0205509
ZNF160 zinc finger protein 160 0.020544
PLSCR2 phospholipid scramblase 2 0.0204131
ANKHD1 ankyrin repeat and KH domain containing 1 0.0203924
ENOX1 ecto-NOX disulfide-thiol exchanger 1 0.0203632
HDLBP high density lipoprotein binding protein 0.0203552
VPS13B vacuolar protein sorting 13 homolog B (yeast) 0.0203389

decreased expression

Symbol Name Standardized Value
EPSTI1 epithelial stromal interaction 1 (breast) -0.154351
LYZ lysozyme -0.11981
PTMA prothymosin, alpha -0.1058
TPT1 tumor protein, translationally-controlled 1 -0.103296
ITGA6 integrin, alpha 6 -0.101425
GMDS GDP-mannose 4,6-dehydratase -0.0985159
ZMYND8 zinc finger, MYND-type containing 8 -0.0933444
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 -0.0904847
C6ORF132 chromosome 6 open reading frame 132 -0.0855108
STS steroid sulfatase (microsomal), isozyme S -0.0846226
HLA-B major histocompatibility complex, class I, B -0.0834773
SPATA13 spermatogenesis associated 13 -0.0800828
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -0.073523
EPHB2 EPH receptor B2 -0.0708754
NPSR1 neuropeptide S receptor 1 -0.0707676
B2M beta-2-microglobulin -0.0676269
RIGI RNA sensor RIG-I -0.0668704
ARHGAP26 Rho GTPase activating protein 26 -0.0665567
PRKCA protein kinase C, alpha -0.0636686
TRIO trio Rho guanine nucleotide exchange factor -0.0630724
LOC102724023 ES1 protein homolog, mitochondrial -0.0614705
MAML2 mastermind-like 2 (Drosophila) -0.0591898
XAF1 XIAP associated factor 1 -0.0578449
RABGAP1L RAB GTPase activating protein 1-like -0.0548095
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.0530179
PERP PERP, TP53 apoptosis effector -0.0516397
SSH2 slingshot protein phosphatase 2 -0.0513564
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 -0.0512597
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 -0.0484129
ANXA4 annexin A4 -0.0462542
TSHZ2 teashirt zinc finger homeobox 2 -0.0459631
LCN2 lipocalin 2 -0.0457499
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0452248
RHOBTB3 Rho-related BTB domain containing 3 -0.0446626
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.0439058
MUC13 mucin 13, cell surface associated -0.0426522
ATP11A ATPase, class VI, type 11A -0.0423259
STAT1 signal transducer and activator of transcription 1, 91kDa -0.041531
MX1 MX dynamin-like GTPase 1 -0.0409471
NCOA7 nuclear receptor coactivator 7 -0.0408615
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -0.0406612
NKD1 naked cuticle homolog 1 (Drosophila) -0.0405625
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 -0.0390746
IGF1R insulin-like growth factor 1 receptor -0.0386396
HLA-E major histocompatibility complex, class I, E -0.0382611
EXT1 exostosin glycosyltransferase 1 -0.038208
FMN1 formin 1 -0.0376877
TFRC transferrin receptor -0.0374355
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.0373181
EPCAM epithelial cell adhesion molecule -0.036375
IFI6 interferon, alpha-inducible protein 6 -0.0356049
IGFBP3 insulin-like growth factor binding protein 3 -0.035502
ABLIM1 actin binding LIM protein 1 -0.0353933
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -0.034497
RRBP1 ribosome binding protein 1 -0.0339869
TMSB10 thymosin beta 10 -0.0337622
MX2 MX dynamin-like GTPase 2 -0.0335789
PARP4 poly (ADP-ribose) polymerase family, member 4 -0.0334376
SORBS1 sorbin and SH3 domain containing 1 -0.0334034
NPEPPS aminopeptidase puromycin sensitive -0.0330267
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic -0.0328157
PATJ PATJ crumbs cell polarity complex component -0.0326511
PDE4D phosphodiesterase 4D, cAMP-specific -0.0318933
SP100 SP100 nuclear antigen -0.0313074
MUC20 mucin 20, cell surface associated -0.031105
GCLC glutamate-cysteine ligase, catalytic subunit -0.0310476
NT5C2 5'-nucleotidase, cytosolic II -0.0308339
HDAC4 histone deacetylase 4 -0.0305008
LLGL2 lethal giant larvae homolog 2 (Drosophila) -0.0304961
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0302838
RUNX1 runt-related transcription factor 1 -0.0300571
TMEM62 transmembrane protein 62 -0.0295394
TRERF1 transcriptional regulating factor 1 -0.0293502
NCKAP5 NCK-associated protein 5 -0.0291725
IFI27 interferon, alpha-inducible protein 27 -0.0288497
PTPRF protein tyrosine phosphatase, receptor type, F -0.0287829
GRK3 G protein-coupled receptor kinase 3 -0.0286686
TM4SF1 transmembrane 4 L six family member 1 -0.028667
HMGB1 high mobility group box 1 -0.0284517
NR6A1 nuclear receptor subfamily 6, group A, member 1 -0.0283503
VDAC1 voltage-dependent anion channel 1 -0.0281645
PTGR1 prostaglandin reductase 1 -0.0277236
SDCBP2 syndecan binding protein (syntenin) 2 -0.0276233
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.0272899
MSI2 musashi RNA-binding protein 2 -0.0271542
HLA-C major histocompatibility complex, class I, C -0.027078
CCND3 cyclin D3 -0.0268143
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0266124
TPM4 tropomyosin 4 -0.0265956
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa -0.0263957
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) -0.0262528
EPB41L1 erythrocyte membrane protein band 4.1-like 1 -0.026232
ACTG1 actin gamma 1 -0.0262249
PMP22 peripheral myelin protein 22 -0.0261805
ITGA1 integrin, alpha 1 -0.0261785
KPNB1 karyopherin (importin) beta 1 -0.0260514
ITGB4 integrin, beta 4 -0.0253609
ADD3 adducin 3 (gamma) -0.0250657
MECOM MDS1 and EVI1 complex locus -0.0250426
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0250005