| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 5-Azacytidine perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 5-Azacytidine_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.179555 |
| ADM | adrenomedullin | 0.12553 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.123721 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.119669 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.111924 |
| TMSB4X | thymosin beta 4, X-linked | 0.096824 |
| COL6A3 | collagen, type VI, alpha 3 | 0.090461 |
| HDAC9 | histone deacetylase 9 | 0.0899989 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0851717 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0789735 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0777529 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0754514 |
| SFTPA2 | surfactant protein A2 | 0.0745373 |
| RND3 | Rho family GTPase 3 | 0.0736423 |
| VMP1 | vacuole membrane protein 1 | 0.0682066 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0661053 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0634423 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0610186 |
| CENPF | centromere protein F, 350/400kDa | 0.0608926 |
| APP | amyloid beta (A4) precursor protein | 0.059867 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0596642 |
| LDHA | lactate dehydrogenase A | 0.0595332 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0583649 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0579065 |
| VEGFA | vascular endothelial growth factor A | 0.0574224 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0562004 |
| FLNB | filamin B, beta | 0.055762 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.053928 |
| CD164 | CD164 molecule, sialomucin | 0.0530382 |
| VCAN | versican | 0.0529387 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0517522 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0511674 |
| CD44 | CD44 molecule (Indian blood group) | 0.0511468 |
| VIM | vimentin | 0.0503233 |
| PDE10A | phosphodiesterase 10A | 0.0499978 |
| CANX | calnexin | 0.0489809 |
| ENO1 | enolase 1, (alpha) | 0.0483071 |
| DST | dystonin | 0.0482572 |
| ANLN | anillin, actin binding protein | 0.0479356 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0476291 |
| PHF3 | PHD finger protein 3 | 0.047554 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0472234 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0471212 |
| SPAG9 | sperm associated antigen 9 | 0.0468889 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0463341 |
| ARRDC3 | arrestin domain containing 3 | 0.0460274 |
| AFDN | afadin, adherens junction formation factor | 0.0456664 |
| PKM | pyruvate kinase, muscle | 0.0455295 |
| RPL4 | ribosomal protein L4 | 0.0426558 |
| JMJD1C | jumonji domain containing 1C | 0.0425148 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0423583 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0421627 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0421409 |
| SERINC1 | serine incorporator 1 | 0.0420332 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0403291 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0402048 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0401854 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0396881 |
| ATP13A3 | ATPase type 13A3 | 0.0394691 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0393973 |
| CDK19 | cyclin-dependent kinase 19 | 0.0392929 |
| NGLY1 | N-glycanase 1 | 0.0392649 |
| RBM6 | RNA binding motif protein 6 | 0.0391269 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0389302 |
| OGA | O-GlcNAcase | 0.0388196 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0386619 |
| RPS3 | ribosomal protein S3 | 0.0383456 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0382369 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0380945 |
| PCBP2 | poly(rC) binding protein 2 | 0.0380713 |
| MKI67 | marker of proliferation Ki-67 | 0.0380711 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0376598 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.037623 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0374637 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0373386 |
| C3 | complement component 3 | 0.0372986 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0372191 |
| CEP250 | centrosomal protein 250kDa | 0.0369924 |
| ZNF451 | zinc finger protein 451 | 0.0365422 |
| RPL41 | ribosomal protein L41 | 0.0365248 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0364019 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0356949 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0355254 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0353288 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0352795 |
| HLA-E | major histocompatibility complex, class I, E | 0.0348958 |
| FNIP1 | folliculin interacting protein 1 | 0.034854 |
| SQSTM1 | sequestosome 1 | 0.0341513 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0334322 |
| FMNL2 | formin-like 2 | 0.0333877 |
| CALR | calreticulin | 0.0333016 |
| SDC4 | syndecan 4 | 0.0329396 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0328371 |
| OPTN | optineurin | 0.032713 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0324383 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0324151 |
| TPM3 | tropomyosin 3 | 0.0322873 |
| EZR | ezrin | 0.0322656 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.0317577 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0316249 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.144963 |
| BICC1 | BicC family RNA binding protein 1 | -0.0923061 |
| IER3 | immediate early response 3 | -0.0779884 |
| FTL | ferritin, light polypeptide | -0.0769361 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0715214 |
| NDRG1 | N-myc downstream regulated 1 | -0.0654172 |
| TMSB10 | thymosin beta 10 | -0.0632514 |
| GPC6 | glypican 6 | -0.0624504 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0583086 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0561692 |
| GNAS | GNAS complex locus | -0.0527866 |
| EGR1 | early growth response 1 | -0.0507247 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0481656 |
| RPS6 | ribosomal protein S6 | -0.0474881 |
| HLA-B | major histocompatibility complex, class I, B | -0.0464459 |
| HMGA1 | high mobility group AT-hook 1 | -0.0432139 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0401847 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0386291 |
| RPL35A | ribosomal protein L35a | -0.0354563 |
| GLIS3 | GLIS family zinc finger 3 | -0.0344226 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.034348 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0337198 |
| CADM1 | cell adhesion molecule 1 | -0.0329113 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0328996 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0319448 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0314903 |
| RPL9 | ribosomal protein L9 | -0.0314263 |
| COL1A1 | collagen, type I, alpha 1 | -0.031195 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0310454 |
| ARF4 | ADP-ribosylation factor 4 | -0.0310169 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0306338 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.030557 |
| RPS8 | ribosomal protein S8 | -0.0304672 |
| RPS24 | ribosomal protein S24 | -0.0303513 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0301245 |
| TFG | TRK-fused gene | -0.0295522 |
| RPLP2 | ribosomal protein, large, P2 | -0.0293885 |
| COL5A1 | collagen, type V, alpha 1 | -0.0287848 |
| TENM2 | teneurin transmembrane protein 2 | -0.0285165 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0284619 |
| DEK | DEK proto-oncogene | -0.0281086 |
| WTAP | Wilms tumor 1 associated protein | -0.0272774 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.027052 |
| RPS19 | ribosomal protein S19 | -0.0268908 |
| CTSD | cathepsin D | -0.0268448 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0268077 |
| RPLP1 | ribosomal protein, large, P1 | -0.0267061 |
| FRMD4A | FERM domain containing 4A | -0.0266038 |
| MX1 | MX dynamin-like GTPase 1 | -0.0255413 |
| RPL13A | ribosomal protein L13a | -0.0251881 |
| RTN4 | reticulon 4 | -0.0250563 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0249747 |
| RIGI | RNA sensor RIG-I | -0.0247823 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0246388 |
| S100A9 | S100 calcium binding protein A9 | -0.0246147 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0242885 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0240589 |
| VCL | vinculin | -0.0239206 |
| RPS21 | ribosomal protein S21 | -0.0238045 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0236102 |
| QKI | QKI, KH domain containing, RNA binding | -0.0230989 |
| SRGN | serglycin | -0.0230669 |
| HLA-C | major histocompatibility complex, class I, C | -0.0226952 |
| FMR1 | fragile X mental retardation 1 | -0.0226708 |
| ACTG1 | actin gamma 1 | -0.0225582 |
| RRBP1 | ribosome binding protein 1 | -0.0224823 |
| CALD1 | caldesmon 1 | -0.0224161 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0224059 |
| B2M | beta-2-microglobulin | -0.0222067 |
| RPS15 | ribosomal protein S15 | -0.0221913 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.022129 |
| BNC2 | basonuclin 2 | -0.021992 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0219067 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0215284 |
| XAF1 | XIAP associated factor 1 | -0.0215113 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0210483 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0209227 |
| ERBIN | erbb2 interacting protein | -0.0209211 |
| FOSL1 | FOS-like antigen 1 | -0.0209074 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0208404 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0207477 |
| AHNAK | AHNAK nucleoprotein | -0.0205549 |
| TMEM123 | transmembrane protein 123 | -0.0199105 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0198814 |
| NRP1 | neuropilin 1 | -0.0198716 |
| FLNA | filamin A, alpha | -0.0196402 |
| JAK2 | Janus kinase 2 | -0.0192362 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | -0.0192241 |
| CCNL1 | cyclin L1 | -0.0188375 |
| KLHL5 | kelch-like family member 5 | -0.0188332 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0187206 |
| SEC24D | SEC24 family member D | -0.018326 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0182266 |
| SEPTIN7 | septin 7 | -0.0182145 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.018191 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0180781 |
| TRIM22 | tripartite motif containing 22 | -0.0180266 |
| RPL36 | ribosomal protein L36 | -0.0178551 |
| PTMA | prothymosin, alpha | -0.0178505 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0177003 |
