5-Azacytidine_SW 1271 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description 5-Azacytidine perturbation in SW 1271 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the 5-Azacytidine_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
CANX calnexin 0.0685806
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 0.0571276
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.05517
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0533282
VIM vimentin 0.0496549
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.0489004
PTMA prothymosin, alpha 0.0470151
TPR translocated promoter region, nuclear basket protein 0.0467643
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0466749
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0460907
ENO1 enolase 1, (alpha) 0.0450929
ELL2 elongation factor, RNA polymerase II, 2 0.0425786
CXCL8 chemokine (C-X-C motif) ligand 8 0.0425579
GOLGA4 golgin A4 0.0424622
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0414938
AKAP12 A kinase (PRKA) anchor protein 12 0.040983
AFF4 AF4/FMR2 family, member 4 0.0405608
CALU calumenin 0.0398011
BZW1 basic leucine zipper and W2 domains 1 0.0397453
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 0.0396911
CLTC clathrin, heavy chain (Hc) 0.0396267
PRRC2C proline-rich coiled-coil 2C 0.0390708
ESYT2 extended synaptotagmin-like protein 2 0.0389232
APLP2 amyloid beta (A4) precursor-like protein 2 0.038746
CALR calreticulin 0.0386545
XRN2 5'-3' exoribonuclease 2 0.0372969
CENPF centromere protein F, 350/400kDa 0.0357696
ASPH aspartate beta-hydroxylase 0.0356882
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.035428
GFPT1 glutamine--fructose-6-phosphate transaminase 1 0.0353023
PKM pyruvate kinase, muscle 0.035199
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.0351343
PYGL phosphorylase, glycogen, liver 0.0350259
YBX3 Y box binding protein 3 0.0348978
LDHA lactate dehydrogenase A 0.0347824
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0343513
PRC1 protein regulator of cytokinesis 1 0.0339234
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.0338772
PGK1 phosphoglycerate kinase 1 0.0335973
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0335625
SPAG9 sperm associated antigen 9 0.0333611
RAD50 RAD50 homolog (S. cerevisiae) 0.0330862
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0323501
BIRC6 baculoviral IAP repeat containing 6 0.0323402
CREBRF CREB3 regulatory factor 0.0321838
RPS3 ribosomal protein S3 0.0315949
GOLGB1 golgin B1 0.031233
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 0.0307004
MATR3 matrin 3 0.0306273
CEP250 centrosomal protein 250kDa 0.0305881
SCRN1 secernin 1 0.0301796
ITCH itchy E3 ubiquitin protein ligase 0.0301177
SKIC3 SKI3 subunit of superkiller complex 0.0296777
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0296346
CKAP5 cytoskeleton associated protein 5 0.0294292
TTC3 tetratricopeptide repeat domain 3 0.0293088
LCORL ligand dependent nuclear receptor corepressor-like 0.0290964
RSF1 remodeling and spacing factor 1 0.0290282
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 0.0286403
EIF1 eukaryotic translation initiation factor 1 0.0279691
GOLIM4 golgi integral membrane protein 4 0.0279287
WDR26 WD repeat domain 26 0.0278812
TXNRD1 thioredoxin reductase 1 0.0277975
SET SET nuclear proto-oncogene 0.0277934
CHD1 chromodomain helicase DNA binding protein 1 0.0277512
SEPTIN7 septin 7 0.027645
RPS27A ribosomal protein S27a 0.0273547
ZNF24 zinc finger protein 24 0.0273207
RPS8 ribosomal protein S8 0.0271398
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.0270882
SEC23A Sec23 homolog A (S. cerevisiae) 0.0268198
ZMYND8 zinc finger, MYND-type containing 8 0.0267539
NGLY1 N-glycanase 1 0.0263204
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0261532
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.0259783
ANKRD37 ankyrin repeat domain 37 0.0259092
AKAP13 A kinase (PRKA) anchor protein 13 0.0258501
CEP192 centrosomal protein 192kDa 0.025821
KLHL24 kelch-like family member 24 0.0257629
SMC4 structural maintenance of chromosomes 4 0.0252509
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) 0.0252476
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 0.0251657
PPIG peptidylprolyl isomerase G (cyclophilin G) 0.0250658
KTN1 kinectin 1 (kinesin receptor) 0.0250444
SRRM2 serine/arginine repetitive matrix 2 0.0249005
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) 0.0248987
MNAT1 MNAT CDK-activating kinase assembly factor 1 0.0246874
CNOT2 CCR4-NOT transcription complex, subunit 2 0.0246852
CLINT1 clathrin interactor 1 0.0245252
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 0.0243886
RPL26 ribosomal protein L26 0.0243459
MKI67 marker of proliferation Ki-67 0.0243107
CEP57 centrosomal protein 57kDa 0.0242683
PICALM phosphatidylinositol binding clathrin assembly protein 0.0242593
TAOK3 TAO kinase 3 0.0241392
PAPOLA poly(A) polymerase alpha 0.0240309
TBC1D15 TBC1 domain family, member 15 0.0238832
NAP1L1 nucleosome assembly protein 1-like 1 0.0236492
S100A9 S100 calcium binding protein A9 0.0235112
TXN2 thioredoxin 2 0.0234187

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.265101
INTS6 integrator complex subunit 6 -0.0594111
DST dystonin -0.0509254
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.0501655
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0471538
PHLDB2 pleckstrin homology-like domain, family B, member 2 -0.0470932
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0429786
EXT1 exostosin glycosyltransferase 1 -0.0428256
RBM39 RNA binding motif protein 39 -0.0411695
HMGA2 high mobility group AT-hook 2 -0.0404324
HDAC9 histone deacetylase 9 -0.0398233
NDRG1 N-myc downstream regulated 1 -0.0373859
PALM2AKAP2 PALM2 and AKAP2 fusion -0.036469
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 -0.0351213
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 -0.0345319
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -0.0344316
ZNF207 zinc finger protein 207 -0.033761
RALY RALY heterogeneous nuclear ribonucleoprotein -0.0330402
N4BP2L2 NEDD4 binding protein 2-like 2 -0.0329035
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta -0.0327003
SAMD4A sterile alpha motif domain containing 4A -0.0326906
RIGI RNA sensor RIG-I -0.0322605
EGR1 early growth response 1 -0.0313667
MAPKAP1 mitogen-activated protein kinase associated protein 1 -0.0311727
MSANTD3 Myb/SANT-like DNA-binding domain containing 3 -0.031098
NABP1 nucleic acid binding protein 1 -0.0310723
OSMR oncostatin M receptor -0.0306793
VCL vinculin -0.0302864
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 -0.0301536
ANXA1 annexin A1 -0.0301078
NKTR natural killer cell triggering receptor -0.0296636
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase -0.0290803
DYNLRB1 dynein, light chain, roadblock-type 1 -0.0289564
PCNX4 pecanex 4 -0.0288304
PHF20 PHD finger protein 20 -0.0287847
ZBTB20 zinc finger and BTB domain containing 20 -0.0280111
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0277334
SLC35F3 solute carrier family 35, member F3 -0.0276813
DCBLD2 discoidin, CUB and LCCL domain containing 2 -0.0276623
ATG7 autophagy related 7 -0.0272941
RDX radixin -0.0271868
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 -0.0271533
RABGAP1 RAB GTPase activating protein 1 -0.027058
ATXN1 ataxin 1 -0.0270355
SRSF3 serine/arginine-rich splicing factor 3 -0.0259864
TUBB4B tubulin, beta 4B class IVb -0.0255808
SATB2 SATB homeobox 2 -0.0251361
ZNF609 zinc finger protein 609 -0.0249719
ENO2 enolase 2 (gamma, neuronal) -0.0244821
LMO7 LIM domain 7 -0.023719
TNRC18 trinucleotide repeat containing 18 -0.0237136
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 -0.0236844
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase -0.0236589
NALCN sodium leak channel, non selective -0.0236372
POTEF POTE ankyrin domain family, member F -0.0231952
IRAK2 interleukin-1 receptor-associated kinase 2 -0.0230154
LRRC49 leucine rich repeat containing 49 -0.022919
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -0.0222427
WDPCP WD repeat containing planar cell polarity effector -0.02224
PCED1B PC-esterase domain containing 1B -0.0221644
TMSB10 thymosin beta 10 -0.0221201
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 -0.0220331
FAF1 Fas (TNFRSF6) associated factor 1 -0.0218389
NUP155 nucleoporin 155kDa -0.0217926
ANKRD11 ankyrin repeat domain 11 -0.0217679
TRA2A transformer 2 alpha homolog (Drosophila) -0.0215387
RNASEH2A ribonuclease H2, subunit A -0.0212
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta -0.0211663
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0211069
LAMA5 laminin, alpha 5 -0.0210507
TBC1D22A TBC1 domain family, member 22A -0.0208761
RTN3 reticulon 3 -0.0207633
E2F3 E2F transcription factor 3 -0.0207308
RUNX1 runt-related transcription factor 1 -0.0207184
SGMS1 sphingomyelin synthase 1 -0.0207044
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 -0.020565
UBE2Z ubiquitin-conjugating enzyme E2Z -0.020516
PNISR PNN-interacting serine/arginine-rich protein -0.0204376
SCLT1 sodium channel and clathrin linker 1 -0.0204075
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) -0.0203978
TCP11L1 t-complex 11, testis-specific-like 1 -0.0203893
NAV3 neuron navigator 3 -0.0203743
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit -0.0201972
GPHN gephyrin -0.0201425
KLF12 Kruppel-like factor 12 -0.0201003
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 -0.0199061
SOS1 son of sevenless homolog 1 (Drosophila) -0.0198786
PRKCA protein kinase C, alpha -0.0198465
CDK5RAP2 CDK5 regulatory subunit associated protein 2 -0.0198165
TPCN1 two pore segment channel 1 -0.0194156
STARD13 StAR-related lipid transfer (START) domain containing 13 -0.0193457
CTTN cortactin -0.0192149
YAP1 Yes-associated protein 1 -0.0190652
GATAD2B GATA zinc finger domain containing 2B -0.0190302
IGF2 insulin-like growth factor 2 -0.018898
CLYBL citrate lyase beta like -0.0188922
BIRC3 baculoviral IAP repeat containing 3 -0.0187468
KPNA4 karyopherin alpha 4 (importin alpha 3) -0.0185194
USP53 ubiquitin specific peptidase 53 -0.0184721
RPS10 ribosomal protein S10 -0.0184334