| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 5-Fluorouracil perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 5-Fluorouracil_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | 0.0950399 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0812347 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0806691 |
| B2M | beta-2-microglobulin | 0.0729443 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0711707 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.0673795 |
| LCN2 | lipocalin 2 | 0.067325 |
| MYO1E | myosin IE | 0.0667426 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0614277 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0599209 |
| ANXA2 | annexin A2 | 0.0559355 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0551377 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0525879 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0522118 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0520512 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0515265 |
| SQSTM1 | sequestosome 1 | 0.0509751 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0488681 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0479517 |
| HLA-B | major histocompatibility complex, class I, B | 0.0444513 |
| EZR | ezrin | 0.0436625 |
| SP100 | SP100 nuclear antigen | 0.0422381 |
| ZNF292 | zinc finger protein 292 | 0.0401278 |
| AREG | amphiregulin | 0.039406 |
| H1-0 | H1.0 linker histone | 0.0391637 |
| MX2 | MX dynamin-like GTPase 2 | 0.0370868 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0369944 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0369792 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0368176 |
| PTMA | prothymosin, alpha | 0.0367666 |
| STK24 | serine/threonine kinase 24 | 0.0367653 |
| UBC | ubiquitin C | 0.0363106 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0359203 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0356583 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0354772 |
| TJP1 | tight junction protein 1 | 0.0349561 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0348563 |
| VCL | vinculin | 0.0348198 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.034481 |
| RNF213 | ring finger protein 213 | 0.0338947 |
| JUN | jun proto-oncogene | 0.0327769 |
| WDR45B | WD repeat domain 45B | 0.0324627 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0315838 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0311662 |
| HLA-E | major histocompatibility complex, class I, E | 0.0310554 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0309916 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0293765 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0293681 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0289658 |
| KLF6 | Kruppel-like factor 6 | 0.0288917 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0287382 |
| PHACTR4 | phosphatase and actin regulator 4 | 0.0286691 |
| VMP1 | vacuole membrane protein 1 | 0.02827 |
| MUC20 | mucin 20, cell surface associated | 0.0282202 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0272259 |
| HLA-A | major histocompatibility complex, class I, A | 0.0271236 |
| EREG | epiregulin | 0.0269726 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0265855 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0258961 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0255267 |
| RBM47 | RNA binding motif protein 47 | 0.0252406 |
| FNIP1 | folliculin interacting protein 1 | 0.0252204 |
| ENO1 | enolase 1, (alpha) | 0.0246885 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0246082 |
| FTL | ferritin, light polypeptide | 0.0245475 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.0244657 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0243851 |
| TMC5 | transmembrane channel-like 5 | 0.0241299 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0240798 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0239871 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0239353 |
| XAF1 | XIAP associated factor 1 | 0.0238836 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0234979 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0234037 |
| GOLGA2 | golgin A2 | 0.0232935 |
| TMEM62 | transmembrane protein 62 | 0.0232349 |
| ITGA6 | integrin, alpha 6 | 0.0231127 |
| LMO7 | LIM domain 7 | 0.0227752 |
| OCLN | occludin | 0.0227174 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.0226591 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.022572 |
| PCED1B | PC-esterase domain containing 1B | 0.0223296 |
| SPATA13 | spermatogenesis associated 13 | 0.0222775 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0221483 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0216314 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0215281 |
| SPAG9 | sperm associated antigen 9 | 0.0214699 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0210535 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0209557 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0207852 |
| RIGI | RNA sensor RIG-I | 0.0206719 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0206256 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.020621 |
| SEC24A | SEC24 family member A | 0.0202723 |
| CD2AP | CD2-associated protein | 0.0202271 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0197086 |
| TXNIP | thioredoxin interacting protein | 0.0196783 |
| SCAPER | S-phase cyclin A-associated protein in the ER | 0.0195491 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0193868 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.019122 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GMDS | GDP-mannose 4,6-dehydratase | -0.0452104 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0427402 |
| RAD51B | RAD51 paralog B | -0.0371801 |
| RNF43 | ring finger protein 43 | -0.0348369 |
| MSI2 | musashi RNA-binding protein 2 | -0.0305971 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.0278452 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0277811 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0266767 |
| ARGLU1 | arginine and glutamate rich 1 | -0.0260338 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0256633 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0252135 |
| PTEN | phosphatase and tensin homolog | -0.0240657 |
| TRERF1 | transcriptional regulating factor 1 | -0.0239428 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0222701 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0216789 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0215909 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0205652 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0200664 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0200451 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0199988 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0198226 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0195707 |
| DST | dystonin | -0.0187438 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0181692 |
| RUNX1 | runt-related transcription factor 1 | -0.0180935 |
| POTEF | POTE ankyrin domain family, member F | -0.0178022 |
| ABHD2 | abhydrolase domain containing 2 | -0.0172547 |
| IFNGR1 | interferon gamma receptor 1 | -0.0171579 |
| GLCE | glucuronic acid epimerase | -0.0167443 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0166089 |
| SNX13 | sorting nexin 13 | -0.0165039 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | -0.0164702 |
| DIAPH1 | diaphanous-related formin 1 | -0.016057 |
| HYOU1 | hypoxia up-regulated 1 | -0.015909 |
| SCFD1 | sec1 family domain containing 1 | -0.0155442 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0155098 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.014932 |
| DSTN | destrin (actin depolymerizing factor) | -0.0145476 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0143661 |
| MICU2 | mitochondrial calcium uptake 2 | -0.0140449 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0140249 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0139843 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0139593 |
| RPS2 | ribosomal protein S2 | -0.0138291 |
| WWOX | WW domain containing oxidoreductase | -0.0136754 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0135534 |
| RB1 | retinoblastoma 1 | -0.0133072 |
| RPS6 | ribosomal protein S6 | -0.0132916 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0132461 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0132378 |
| FAT1 | FAT atypical cadherin 1 | -0.0130222 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.0128013 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0127922 |
| TMEM39A | transmembrane protein 39A | -0.0126687 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.012659 |
| HPCAL1 | hippocalcin-like 1 | -0.0126553 |
| RBM25 | RNA binding motif protein 25 | -0.0125919 |
| NCOA2 | nuclear receptor coactivator 2 | -0.0124753 |
| TNS4 | tensin 4 | -0.0124372 |
| PHF3 | PHD finger protein 3 | -0.0123286 |
| MAP7 | microtubule-associated protein 7 | -0.0123007 |
| CALR | calreticulin | -0.0120059 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | -0.0119229 |
| SMAD3 | SMAD family member 3 | -0.0118375 |
| MED13L | mediator complex subunit 13-like | -0.0117132 |
| EFNB2 | ephrin-B2 | -0.0116706 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | -0.0116691 |
| WDR26 | WD repeat domain 26 | -0.011658 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.011549 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | -0.0115225 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.0113806 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | -0.0113724 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.011368 |
| BRD4 | bromodomain containing 4 | -0.0112676 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0112615 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0111872 |
| KIAA1671 | KIAA1671 | -0.0111396 |
| NUP50 | nucleoporin 50kDa | -0.0110702 |
| LNX2 | ligand of numb-protein X 2 | -0.0109574 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.010933 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0108644 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | -0.0108107 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.010789 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0106816 |
| PIWIL1 | piwi-like RNA-mediated gene silencing 1 | -0.0106251 |
| EDEM3 | ER degradation enhancer, mannosidase alpha-like 3 | -0.0103521 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0102669 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor | -0.010243 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | -0.0102355 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.0102332 |
| SRSF5 | serine/arginine-rich splicing factor 5 | -0.0101921 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | -0.0101763 |
| DOCK9 | dedicator of cytokinesis 9 | -0.0101078 |
| BTBD10 | BTB (POZ) domain containing 10 | -0.0100967 |
| RPLP1 | ribosomal protein, large, P1 | -0.0100843 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0100561 |
| ZNF706 | zinc finger protein 706 | -0.010023 |
| PLSCR2 | phospholipid scramblase 2 | -0.0100123 |
| FNDC3B | fibronectin type III domain containing 3B | -0.00998703 |
| RPS12 | ribosomal protein S12 | -0.00996742 |
