| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 5-Fluorouracil perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 5-Fluorouracil_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.138464 |
| EREG | epiregulin | 0.102362 |
| GOLGA4 | golgin A4 | 0.0844484 |
| AREG | amphiregulin | 0.0809144 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0758898 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0620968 |
| RNF43 | ring finger protein 43 | 0.0591886 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0538235 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0526249 |
| GDF15 | growth differentiation factor 15 | 0.0524207 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0509785 |
| PTEN | phosphatase and tensin homolog | 0.0475304 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0469065 |
| INSIG1 | insulin induced gene 1 | 0.046306 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.046087 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0436562 |
| RNF145 | ring finger protein 145 | 0.0431194 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0430315 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0426216 |
| TPD52 | tumor protein D52 | 0.0412337 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.0407004 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0405039 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0402664 |
| OGA | O-GlcNAcase | 0.0397487 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0393765 |
| H1-0 | H1.0 linker histone | 0.0391901 |
| FAM13A | family with sequence similarity 13, member A | 0.0388946 |
| RPLP0 | ribosomal protein, large, P0 | 0.0380839 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0373152 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0372966 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0368622 |
| SETD5 | SET domain containing 5 | 0.0356972 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0356172 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0344954 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0342845 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0341286 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0334133 |
| SPPL3 | signal peptide peptidase like 3 | 0.0332253 |
| UBC | ubiquitin C | 0.0330312 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0317592 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0314822 |
| SHROOM3 | shroom family member 3 | 0.0313932 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0313853 |
| CANX | calnexin | 0.0313385 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0312446 |
| PGK1 | phosphoglycerate kinase 1 | 0.0310583 |
| EPCAM | epithelial cell adhesion molecule | 0.0310431 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0305234 |
| EXOC1 | exocyst complex component 1 | 0.0300895 |
| TXNIP | thioredoxin interacting protein | 0.0298143 |
| PCDHB16 | protocadherin beta 16 | 0.0298004 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0295266 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0295237 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0293775 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0293527 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0292954 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0290785 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0289681 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0287864 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.028297 |
| CDK19 | cyclin-dependent kinase 19 | 0.0276768 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0273491 |
| ATXN1 | ataxin 1 | 0.0273032 |
| NF1 | neurofibromin 1 | 0.0272859 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0272643 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0271973 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0271383 |
| ERBIN | erbb2 interacting protein | 0.0268926 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0268462 |
| USP34 | ubiquitin specific peptidase 34 | 0.0261779 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.025878 |
| TMF1 | TATA element modulatory factor 1 | 0.0255079 |
| COG5 | component of oligomeric golgi complex 5 | 0.0254782 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0254378 |
| THOC2 | THO complex 2 | 0.0252688 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0248496 |
| USP6NL | USP6 N-terminal like | 0.0247183 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0245177 |
| ZFR | zinc finger RNA binding protein | 0.0244688 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0243813 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0242887 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0242117 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | 0.0239757 |
| DSPP | dentin sialophosphoprotein | 0.0239626 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0239041 |
| NKTR | natural killer cell triggering receptor | 0.023858 |
| KIF5B | kinesin family member 5B | 0.0236921 |
| YTHDC1 | YTH domain containing 1 | 0.0236906 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0236629 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.023646 |
| WASF2 | WAS protein family, member 2 | 0.023571 |
| FNIP1 | folliculin interacting protein 1 | 0.0235658 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0235466 |
| CEP350 | centrosomal protein 350kDa | 0.0235314 |
| CARD16 | caspase recruitment domain family, member 16 | 0.023477 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0234669 |
| PRSS3 | protease, serine, 3 | 0.0234595 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0233662 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0231055 |
| METTL15 | methyltransferase like 15 | 0.023031 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.188272 |
| NPSR1 | neuropeptide S receptor 1 | -0.151872 |
| PTMA | prothymosin, alpha | -0.123737 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.116008 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.113829 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0955435 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0712016 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0702268 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0689535 |
| VCL | vinculin | -0.0668208 |
| ASPH | aspartate beta-hydroxylase | -0.0648707 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0569309 |
| ONECUT3 | one cut homeobox 3 | -0.0566948 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0552834 |
| ACTG1 | actin gamma 1 | -0.0541911 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0529206 |
| MT2A | metallothionein 2A | -0.0520975 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0506491 |
| RPS8 | ribosomal protein S8 | -0.0495793 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0478212 |
| EGFR | epidermal growth factor receptor | -0.0477943 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0466213 |
| RPS6 | ribosomal protein S6 | -0.0453998 |
| ACTN4 | actinin, alpha 4 | -0.0438351 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.04281 |
| FLNB | filamin B, beta | -0.0418762 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0414449 |
| POTEF | POTE ankyrin domain family, member F | -0.0399452 |
| HMGA1 | high mobility group AT-hook 1 | -0.0397391 |
| RPL23 | ribosomal protein L23 | -0.0397085 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0390632 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0377087 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0376353 |
| HMGB1 | high mobility group box 1 | -0.0358291 |
| RPS19 | ribosomal protein S19 | -0.0358052 |
| SVIL | supervillin | -0.0355331 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0352134 |
| RNF217 | ring finger protein 217 | -0.0351215 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0346048 |
| RAD51B | RAD51 paralog B | -0.0345488 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0342857 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0337811 |
| FHIT | fragile histidine triad | -0.0328585 |
| RPL36 | ribosomal protein L36 | -0.0326293 |
| PDLIM5 | PDZ and LIM domain 5 | -0.031409 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0313807 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0311553 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0308234 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0299981 |
| ARHGAP6 | Rho GTPase activating protein 6 | -0.029845 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0295433 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0294081 |
| LSAMP | limbic system-associated membrane protein | -0.0291982 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0289731 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0288443 |
| RPL35A | ribosomal protein L35a | -0.0284962 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0281771 |
| FAT1 | FAT atypical cadherin 1 | -0.0277604 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0276475 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0276433 |
| MUC17 | mucin 17, cell surface associated | -0.0273236 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.027214 |
| TUBA1B | tubulin, alpha 1b | -0.0271548 |
| TFF1 | trefoil factor 1 | -0.0270612 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | -0.0269716 |
| LAMA4 | laminin, alpha 4 | -0.0266448 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0264667 |
| S100A6 | S100 calcium binding protein A6 | -0.0260577 |
| S100A10 | S100 calcium binding protein A10 | -0.0255307 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0254917 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0253767 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0252188 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0251102 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0250481 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0249471 |
| TPM1 | tropomyosin 1 (alpha) | -0.0249198 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0249075 |
| RCOR1 | REST corepressor 1 | -0.0247799 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.024596 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.0244071 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0241416 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.023991 |
| RPL9 | ribosomal protein L9 | -0.0239166 |
| ANXA1 | annexin A1 | -0.0235763 |
| RPL18 | ribosomal protein L18 | -0.023553 |
| RPL34 | ribosomal protein L34 | -0.0234853 |
| MT1X | metallothionein 1X | -0.023483 |
| TPM4 | tropomyosin 4 | -0.0234787 |
| RPS17 | ribosomal protein S17 | -0.0234735 |
| MECOM | MDS1 and EVI1 complex locus | -0.0228296 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | -0.022795 |
| DENND1A | DENN/MADD domain containing 1A | -0.0226855 |
| KLK10 | kallikrein-related peptidase 10 | -0.0225787 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0224748 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0223784 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0223399 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0222039 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0221507 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0220668 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.021885 |
