| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 5-Fluorouracil perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 5-Fluorouracil_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.136274 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.103583 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0859772 |
| FNIP1 | folliculin interacting protein 1 | 0.0838482 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0783384 |
| JMJD1C | jumonji domain containing 1C | 0.0769699 |
| NAV2 | neuron navigator 2 | 0.0657428 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0588651 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0587053 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0580675 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0572361 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0547641 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.053651 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0523869 |
| NDRG1 | N-myc downstream regulated 1 | 0.0520902 |
| ATXN1 | ataxin 1 | 0.0511052 |
| PDE10A | phosphodiesterase 10A | 0.0509675 |
| GOLGA4 | golgin A4 | 0.0500111 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0498386 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0488065 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0482938 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0461912 |
| ADM | adrenomedullin | 0.0457965 |
| PRELID2 | PRELI domain containing 2 | 0.0457083 |
| DST | dystonin | 0.0447896 |
| YEATS2 | YEATS domain containing 2 | 0.044102 |
| STC1 | stanniocalcin 1 | 0.043541 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0431981 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0417371 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0417367 |
| PHF21A | PHD finger protein 21A | 0.0416772 |
| TNS3 | tensin 3 | 0.041328 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0411352 |
| HDAC9 | histone deacetylase 9 | 0.040677 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0404887 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0397763 |
| CDK19 | cyclin-dependent kinase 19 | 0.0378244 |
| RAI14 | retinoic acid induced 14 | 0.0372351 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0370827 |
| PLIN2 | perilipin 2 | 0.0368218 |
| MMP12 | matrix metallopeptidase 12 | 0.0365435 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0361878 |
| FMNL2 | formin-like 2 | 0.0358355 |
| ARFGEF3 | ARFGEF family member 3 | 0.0356281 |
| PHF3 | PHD finger protein 3 | 0.0350556 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0343975 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0341577 |
| RND3 | Rho family GTPase 3 | 0.0340759 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0337067 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.033482 |
| LRRC7 | leucine rich repeat containing 7 | 0.0334183 |
| CD44 | CD44 molecule (Indian blood group) | 0.0333284 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0329657 |
| EGFR | epidermal growth factor receptor | 0.0326902 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0326692 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0326606 |
| PCBP3 | poly(rC) binding protein 3 | 0.0325542 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0324065 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0323947 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0323052 |
| FLNB | filamin B, beta | 0.0322963 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0321387 |
| TMEM14B | transmembrane protein 14B | 0.0313958 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0304392 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0302455 |
| CD109 | CD109 molecule | 0.0300697 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0293785 |
| RAD51B | RAD51 paralog B | 0.0291851 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0290898 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0288556 |
| EXOC4 | exocyst complex component 4 | 0.0285986 |
| USP47 | ubiquitin specific peptidase 47 | 0.0285778 |
| NGLY1 | N-glycanase 1 | 0.0283859 |
| MYO9A | myosin IXA | 0.028253 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0281525 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0279801 |
| CERT1 | ceramide transporter 1 | 0.027558 |
| TMEM132D | transmembrane protein 132D | 0.0275268 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0274936 |
| VEGFA | vascular endothelial growth factor A | 0.0274819 |
| CCBE1 | collagen and calcium binding EGF domains 1 | 0.0274174 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0271613 |
| FAM114A1 | family with sequence similarity 114, member A1 | 0.0271521 |
| COPA | coatomer protein complex, subunit alpha | 0.0270992 |
| CREBRF | CREB3 regulatory factor | 0.0268174 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0268083 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0266405 |
| SBF2 | SET binding factor 2 | 0.0265809 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0263101 |
| SEPTIN9 | septin 9 | 0.0262224 |
| ZNF638 | zinc finger protein 638 | 0.0257754 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0256249 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0255013 |
| ENO1 | enolase 1, (alpha) | 0.025374 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0252347 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0251834 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.0251516 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0251385 |
| PTEN | phosphatase and tensin homolog | 0.0249981 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0249066 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.139365 |
| FN1 | fibronectin 1 | -0.117181 |
| BICC1 | BicC family RNA binding protein 1 | -0.104225 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0961596 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0842672 |
| VCL | vinculin | -0.0767127 |
| TMSB10 | thymosin beta 10 | -0.0760692 |
| GLIS3 | GLIS family zinc finger 3 | -0.0701009 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0684679 |
| RPS6 | ribosomal protein S6 | -0.0643129 |
| RPL23 | ribosomal protein L23 | -0.0629625 |
| HLA-B | major histocompatibility complex, class I, B | -0.0598651 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0597968 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0583106 |
| THBS1 | thrombospondin 1 | -0.055932 |
| FTL | ferritin, light polypeptide | -0.0545607 |
| VIM | vimentin | -0.0544241 |
| EXT1 | exostosin glycosyltransferase 1 | -0.053689 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0511732 |
| RPS4X | ribosomal protein S4, X-linked | -0.0490829 |
| RPL19 | ribosomal protein L19 | -0.0474422 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0458022 |
| WTAP | Wilms tumor 1 associated protein | -0.0452324 |
| ANXA2 | annexin A2 | -0.0423055 |
| RPLP1 | ribosomal protein, large, P1 | -0.0421994 |
| IER3 | immediate early response 3 | -0.0398976 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0393663 |
| QKI | QKI, KH domain containing, RNA binding | -0.0383566 |
| FLNA | filamin A, alpha | -0.0383299 |
| RPS24 | ribosomal protein S24 | -0.0379732 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0369081 |
| RPS12 | ribosomal protein S12 | -0.0365715 |
| SMAD3 | SMAD family member 3 | -0.0357147 |
| B2M | beta-2-microglobulin | -0.0353699 |
| RACK1 | receptor for activated C kinase 1 | -0.0351823 |
| RIGI | RNA sensor RIG-I | -0.0351302 |
| RPS8 | ribosomal protein S8 | -0.0342878 |
| ICAM1 | intercellular adhesion molecule 1 | -0.03423 |
| YBX1 | Y box binding protein 1 | -0.0335849 |
| RPS19 | ribosomal protein S19 | -0.0335034 |
| RPL5 | ribosomal protein L5 | -0.0332648 |
| RPL36 | ribosomal protein L36 | -0.0331389 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0331368 |
| PALLD | palladin, cytoskeletal associated protein | -0.0331368 |
| HLA-C | major histocompatibility complex, class I, C | -0.0328104 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0322857 |
| COL6A3 | collagen, type VI, alpha 3 | -0.032166 |
| RPL36A | ribosomal protein L36a | -0.0320628 |
| RPLP0 | ribosomal protein, large, P0 | -0.0311646 |
| RPS2 | ribosomal protein S2 | -0.0311632 |
| FRMD4A | FERM domain containing 4A | -0.0308722 |
| THBS2 | thrombospondin 2 | -0.0306208 |
| ACTG1 | actin gamma 1 | -0.0301797 |
| NABP1 | nucleic acid binding protein 1 | -0.0300872 |
| RPL32 | ribosomal protein L32 | -0.0298874 |
| KYNU | kynureninase | -0.0281843 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0280231 |
| CRY1 | cryptochrome circadian clock 1 | -0.0279952 |
| TUBB | tubulin, beta class I | -0.0278153 |
| CDK17 | cyclin-dependent kinase 17 | -0.0276492 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0276103 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0273104 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0267042 |
| RPL12 | ribosomal protein L12 | -0.0264204 |
| GNAS | GNAS complex locus | -0.0264045 |
| TNNC1 | troponin C type 1 (slow) | -0.0260594 |
| TPM1 | tropomyosin 1 (alpha) | -0.0259276 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0256605 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0256069 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0254184 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0253635 |
| S100A9 | S100 calcium binding protein A9 | -0.0253231 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0248633 |
| RPL26 | ribosomal protein L26 | -0.0246842 |
| ACTN1 | actinin, alpha 1 | -0.0240532 |
| RTN4 | reticulon 4 | -0.0237178 |
| RPL38 | ribosomal protein L38 | -0.0235637 |
| GOPC | golgi-associated PDZ and coiled-coil motif containing | -0.0235133 |
| POTEF | POTE ankyrin domain family, member F | -0.023431 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0232097 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.023191 |
| RPL35 | ribosomal protein L35 | -0.0231301 |
| ENAH | enabled homolog (Drosophila) | -0.0231127 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0228685 |
| RNF213 | ring finger protein 213 | -0.0227119 |
| TXNRD1 | thioredoxin reductase 1 | -0.0221137 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0217193 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0217014 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0216352 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0211953 |
| TRIM22 | tripartite motif containing 22 | -0.0211041 |
| CORO1C | coronin, actin binding protein, 1C | -0.0210793 |
| MT2A | metallothionein 2A | -0.0209988 |
| RPLP2 | ribosomal protein, large, P2 | -0.0209982 |
| MKI67 | marker of proliferation Ki-67 | -0.0208755 |
| DCBLD1 | discoidin, CUB and LCCL domain containing 1 | -0.0208678 |
| SH3RF2 | SH3 domain containing ring finger 2 | -0.0204744 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0204613 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.020011 |
| SRGN | serglycin | -0.0199506 |
