| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 5-Fluorouracil perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 5-Fluorouracil_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.095704 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0791561 |
| CD44 | CD44 molecule (Indian blood group) | 0.0789905 |
| PTMA | prothymosin, alpha | 0.0720274 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0682742 |
| CDH13 | cadherin 13 | 0.0673428 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0623142 |
| PTGES2 | prostaglandin E synthase 2 | 0.0620198 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0600714 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.051431 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0490971 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.0476489 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0468906 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0455403 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0452245 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0443849 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0443308 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0439664 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0439177 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0439028 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.043655 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.042861 |
| TFG | TRK-fused gene | 0.0427177 |
| GOLGB1 | golgin B1 | 0.0415007 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0412156 |
| TPR | translocated promoter region, nuclear basket protein | 0.0411816 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.0410689 |
| PTN | pleiotrophin | 0.0407656 |
| ZNF207 | zinc finger protein 207 | 0.040639 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0400608 |
| DIAPH3 | diaphanous-related formin 3 | 0.0391812 |
| COG6 | component of oligomeric golgi complex 6 | 0.0390152 |
| PTK2 | protein tyrosine kinase 2 | 0.038617 |
| CDK6 | cyclin-dependent kinase 6 | 0.0385567 |
| MTDH | metadherin | 0.0384806 |
| FMNL2 | formin-like 2 | 0.0384114 |
| GOLGA4 | golgin A4 | 0.0383205 |
| B2M | beta-2-microglobulin | 0.0379286 |
| MYADM | myeloid-associated differentiation marker | 0.0376393 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0365518 |
| TMSB10 | thymosin beta 10 | 0.0363051 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0361245 |
| IL6 | interleukin 6 | 0.0361105 |
| SEC24A | SEC24 family member A | 0.035469 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0351723 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0349 |
| ARRDC3 | arrestin domain containing 3 | 0.034708 |
| SBF2 | SET binding factor 2 | 0.0343947 |
| COPA | coatomer protein complex, subunit alpha | 0.0340544 |
| TMEM165 | transmembrane protein 165 | 0.0340348 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0337188 |
| SETX | senataxin | 0.033662 |
| PAPOLA | poly(A) polymerase alpha | 0.0336525 |
| SEC24D | SEC24 family member D | 0.0334245 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0333333 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0330609 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0328415 |
| STK17A | serine/threonine kinase 17a | 0.0327775 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0326994 |
| JMJD1C | jumonji domain containing 1C | 0.0325865 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0319415 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0314927 |
| METTL15 | methyltransferase like 15 | 0.0314509 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0314129 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0313913 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0313188 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.0310018 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0308496 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0306129 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0306039 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0302946 |
| CD99 | CD99 molecule | 0.0300188 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.0299153 |
| CAB39 | calcium binding protein 39 | 0.0295723 |
| ADNP | activity-dependent neuroprotector homeobox | 0.0293732 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0289012 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.0287749 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.028755 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0287387 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0287231 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0286772 |
| MSN | moesin | 0.0286753 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0286253 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.0284593 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0283836 |
| RABGAP1 | RAB GTPase activating protein 1 | 0.0283522 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0282975 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0282788 |
| TNPO3 | transportin 3 | 0.0280897 |
| WASF2 | WAS protein family, member 2 | 0.028044 |
| MAP1B | microtubule-associated protein 1B | 0.0280327 |
| MT2A | metallothionein 2A | 0.0279475 |
| NAV2 | neuron navigator 2 | 0.0278703 |
| XPO6 | exportin 6 | 0.0278438 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0278325 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0277416 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0277256 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0276804 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.027607 |
| STC1 | stanniocalcin 1 | 0.0275516 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.216942 |
| PRELID2 | PRELI domain containing 2 | -0.0756389 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0699532 |
| COL1A2 | collagen, type I, alpha 2 | -0.0645319 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0556657 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0556525 |
| FBXO11 | F-box protein 11 | -0.0545936 |
| LDHA | lactate dehydrogenase A | -0.0534946 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0525828 |
| H3-3B | H3.3 histone B | -0.0518422 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0495428 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0491854 |
| CALD1 | caldesmon 1 | -0.0484735 |
| HLA-B | major histocompatibility complex, class I, B | -0.04782 |
| AUTS2 | autism susceptibility candidate 2 | -0.0461952 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0440175 |
| VCL | vinculin | -0.042659 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0410836 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0410166 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.039708 |
| SUCO | SUN domain containing ossification factor | -0.0396535 |
| RNF216 | ring finger protein 216 | -0.038511 |
| ANXA2 | annexin A2 | -0.0384857 |
| SQSTM1 | sequestosome 1 | -0.0382822 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0382408 |
| MEF2A | myocyte enhancer factor 2A | -0.0378223 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0374166 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.037416 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0366863 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0363706 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0363617 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0358474 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.0357476 |
| ANO6 | anoctamin 6 | -0.0352718 |
| RUNX1 | runt-related transcription factor 1 | -0.0351955 |
| MYOF | myoferlin | -0.0350586 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0349671 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0348752 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0348479 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0345431 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0343375 |
| SPAG9 | sperm associated antigen 9 | -0.0342689 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.033874 |
| RPL11 | ribosomal protein L11 | -0.0336223 |
| LCOR | ligand dependent nuclear receptor corepressor | -0.0335393 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0330513 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0330024 |
| SMAD3 | SMAD family member 3 | -0.0327832 |
| RPL35A | ribosomal protein L35a | -0.0321043 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0320319 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0316192 |
| TSPAN9 | tetraspanin 9 | -0.0315777 |
| LMNA | lamin A/C | -0.0314554 |
| INHBA | inhibin, beta A | -0.0314078 |
| FAM162A | family with sequence similarity 162, member A | -0.0313492 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0313398 |
| RYK | receptor-like tyrosine kinase | -0.0312736 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0312217 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0311868 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0310985 |
| ERBIN | erbb2 interacting protein | -0.0310682 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0309694 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0308291 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0304461 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0302832 |
| LOX | lysyl oxidase | -0.0300393 |
| DENND4C | DENN/MADD domain containing 4C | -0.0294592 |
| RYBP | RING1 and YY1 binding protein | -0.0293253 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0291358 |
| KLC1 | kinesin light chain 1 | -0.0288089 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.0286867 |
| AHR | aryl hydrocarbon receptor | -0.0286476 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0280518 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.027914 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.0277121 |
| PDZD2 | PDZ domain containing 2 | -0.0276986 |
| NDRG1 | N-myc downstream regulated 1 | -0.0274372 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0269866 |
| ABHD12 | abhydrolase domain containing 12 | -0.0265564 |
| JAG1 | jagged 1 | -0.0265445 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.026488 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.0264572 |
| SNX13 | sorting nexin 13 | -0.0264441 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0261988 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0260664 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0260102 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0258217 |
| PKM | pyruvate kinase, muscle | -0.0257837 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0256368 |
| LMAN2 | lectin, mannose-binding 2 | -0.025443 |
| PALLD | palladin, cytoskeletal associated protein | -0.0254404 |
| ATP13A3 | ATPase type 13A3 | -0.025349 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0252785 |
| MTREX | Mtr4 exosome RNA helicase | -0.0252453 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0251274 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0250375 |
| ARSJ | arylsulfatase family, member J | -0.024982 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0249338 |
| RPS27A | ribosomal protein S27a | -0.024823 |
| BPTF | bromodomain PHD finger transcription factor | -0.0247748 |
