| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 5-Fluorouracil perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 5-Fluorouracil_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.138537 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0773509 |
| COPA | coatomer protein complex, subunit alpha | 0.0716939 |
| GOLGA4 | golgin A4 | 0.0665308 |
| TXNIP | thioredoxin interacting protein | 0.0550736 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0549085 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.052909 |
| SUCO | SUN domain containing ossification factor | 0.0524815 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0483091 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0466269 |
| AHR | aryl hydrocarbon receptor | 0.0458862 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0444618 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0436 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0428333 |
| OGA | O-GlcNAcase | 0.0421975 |
| COG5 | component of oligomeric golgi complex 5 | 0.0409613 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.0407121 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0399754 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0395469 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0387109 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0386661 |
| TPR | translocated promoter region, nuclear basket protein | 0.0382478 |
| COG6 | component of oligomeric golgi complex 6 | 0.0378779 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0377709 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0372458 |
| RO60 | Ro60, Y RNA binding protein | 0.0363202 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0355132 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0352354 |
| WAC | WW domain containing adaptor with coiled-coil | 0.035195 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0350959 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.035091 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0350828 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0349587 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0349444 |
| SMOX | spermine oxidase | 0.0348736 |
| SEC24A | SEC24 family member A | 0.0341865 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0337793 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0336103 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0332568 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0331414 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0330228 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0320581 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0320502 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.031999 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0316509 |
| WDR26 | WD repeat domain 26 | 0.0311662 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0310901 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0304778 |
| RAB18 | RAB18, member RAS oncogene family | 0.0304703 |
| DUSP5 | dual specificity phosphatase 5 | 0.0304444 |
| CTBP2 | C-terminal binding protein 2 | 0.0301812 |
| THOC2 | THO complex 2 | 0.0301595 |
| DENND5B | DENN/MADD domain containing 5B | 0.0299004 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0296972 |
| GOLT1B | golgi transport 1B | 0.0296544 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0287714 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.028729 |
| YTHDC1 | YTH domain containing 1 | 0.0286439 |
| EREG | epiregulin | 0.0285027 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0283331 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0280844 |
| CDC27 | cell division cycle 27 | 0.0280444 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0279934 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0278552 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0278287 |
| WDR45B | WD repeat domain 45B | 0.027817 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0276244 |
| OSMR | oncostatin M receptor | 0.0274548 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0272365 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0270777 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 | 0.0265841 |
| ETNK1 | ethanolamine kinase 1 | 0.0264296 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0263111 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0262797 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0257301 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0257 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0255495 |
| ZNF638 | zinc finger protein 638 | 0.0254936 |
| SFXN1 | sideroflexin 1 | 0.0254288 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0254053 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0251058 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0250683 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0250256 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0248864 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0248309 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0247399 |
| CREBRF | CREB3 regulatory factor | 0.0246466 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.024392 |
| TMF1 | TATA element modulatory factor 1 | 0.0242002 |
| USP53 | ubiquitin specific peptidase 53 | 0.0241829 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0239769 |
| EPN2 | epsin 2 | 0.0239093 |
| RBM25 | RNA binding motif protein 25 | 0.023597 |
| MATR3 | matrin 3 | 0.0235723 |
| MAP2K4 | mitogen-activated protein kinase kinase 4 | 0.0235206 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0235077 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.023349 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0233427 |
| CD109 | CD109 molecule | 0.0232139 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0231248 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.179425 |
| NRG1 | neuregulin 1 | -0.174497 |
| TMSB10 | thymosin beta 10 | -0.13164 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.121396 |
| PTMA | prothymosin, alpha | -0.121103 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.113115 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.109808 |
| HMGA2 | high mobility group AT-hook 2 | -0.104178 |
| MT2A | metallothionein 2A | -0.0947307 |
| HLA-B | major histocompatibility complex, class I, B | -0.0811557 |
| VIM | vimentin | -0.0779353 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0710393 |
| RPL35A | ribosomal protein L35a | -0.0696772 |
| ASPH | aspartate beta-hydroxylase | -0.0657901 |
| S100A6 | S100 calcium binding protein A6 | -0.0624539 |
| MAP1B | microtubule-associated protein 1B | -0.0599453 |
| HMGA1 | high mobility group AT-hook 1 | -0.0588759 |
| POTEF | POTE ankyrin domain family, member F | -0.0569158 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0527608 |
| S100A10 | S100 calcium binding protein A10 | -0.0525932 |
| FTL | ferritin, light polypeptide | -0.051053 |
| ACTG1 | actin gamma 1 | -0.0507903 |
| KLHL5 | kelch-like family member 5 | -0.0502577 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0498954 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0492882 |
| RPL26 | ribosomal protein L26 | -0.0492055 |
| RPS6 | ribosomal protein S6 | -0.048625 |
| RPL23 | ribosomal protein L23 | -0.0476188 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0467326 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0463392 |
| LMNA | lamin A/C | -0.0451821 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0445444 |
| B2M | beta-2-microglobulin | -0.044358 |
| RPL9 | ribosomal protein L9 | -0.0431913 |
| SQSTM1 | sequestosome 1 | -0.0427125 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0419972 |
| IER3 | immediate early response 3 | -0.0418887 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0415411 |
| RPS24 | ribosomal protein S24 | -0.0411832 |
| RPL12 | ribosomal protein L12 | -0.040823 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0402158 |
| PTK2 | protein tyrosine kinase 2 | -0.0396716 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0395447 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0395286 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0377789 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0377316 |
| STC2 | stanniocalcin 2 | -0.0374763 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.037309 |
| RPS19 | ribosomal protein S19 | -0.0372555 |
| TPI1 | triosephosphate isomerase 1 | -0.0369289 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0367616 |
| RPL37 | ribosomal protein L37 | -0.0366827 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0361476 |
| RPL31 | ribosomal protein L31 | -0.03591 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0351704 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0350577 |
| RNF213 | ring finger protein 213 | -0.0346385 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.033881 |
| RPL38 | ribosomal protein L38 | -0.033834 |
| NTN4 | netrin 4 | -0.0328072 |
| EGR1 | early growth response 1 | -0.0322187 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0313232 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0309822 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0309058 |
| NRP1 | neuropilin 1 | -0.030745 |
| RPS8 | ribosomal protein S8 | -0.0306163 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0305017 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0295534 |
| TPM4 | tropomyosin 4 | -0.0293534 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0291845 |
| RPL37A | ribosomal protein L37a | -0.0291206 |
| SYT1 | synaptotagmin I | -0.0290085 |
| RPS21 | ribosomal protein S21 | -0.0283756 |
| RPS27 | ribosomal protein S27 | -0.0283342 |
| RPL34 | ribosomal protein L34 | -0.0282757 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0279 |
| MKI67 | marker of proliferation Ki-67 | -0.0277045 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0272595 |
| TMSB4X | thymosin beta 4, X-linked | -0.0270415 |
| IFI44L | interferon-induced protein 44-like | -0.0266803 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0262495 |
| RPLP2 | ribosomal protein, large, P2 | -0.0257882 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0257467 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0257317 |
| RPS25 | ribosomal protein S25 | -0.0251402 |
| MX2 | MX dynamin-like GTPase 2 | -0.025116 |
| HLA-A | major histocompatibility complex, class I, A | -0.0250239 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0248417 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.024529 |
| HMGB1 | high mobility group box 1 | -0.0242597 |
| TENM4 | teneurin transmembrane protein 4 | -0.0242128 |
| OXR1 | oxidation resistance 1 | -0.0239626 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0239625 |
| RPS23 | ribosomal protein S23 | -0.0236043 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0232818 |
| RPS20 | ribosomal protein S20 | -0.0229974 |
| TMEM156 | transmembrane protein 156 | -0.0229968 |
| GPATCH2L | G patch domain containing 2-like | -0.0229812 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0226039 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0222706 |
