5151277-903 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the 5151277-903 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARL4C ADP-ribosylation factor-like 4C
ATAD5 ATPase family, AAA domain containing 5
BCORL1 BCL6 corepressor-like 1
C14ORF105 chromosome 14 open reading frame 105
C9ORF9 chromosome 9 open reading frame 9
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CACYBP calcyclin binding protein
CCNJL cyclin J-like
CFLAR CASP8 and FADD-like apoptosis regulator
CSNK1G1 casein kinase 1, gamma 1
CYHR1 cysteine/histidine-rich 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DEGS1 delta(4)-desaturase, sphingolipid 1
DIAPH1 diaphanous-related formin 1
DMWD dystrophia myotonica, WD repeat containing
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DPYSL4 dihydropyrimidinase-like 4
DYSF dysferlin
FANCC Fanconi anemia, complementation group C
FAS Fas cell surface death receptor
FBXO2 F-box protein 2
FGF23 fibroblast growth factor 23
FOXJ3 forkhead box J3
GCLM glutamate-cysteine ligase, modifier subunit
GLI3 GLI family zinc finger 3
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIRA histone cell cycle regulator
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HMOX1 heme oxygenase 1
HNRNPL heterogeneous nuclear ribonucleoprotein L
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
INADL InaD-like (Drosophila)
ITGB5 integrin, beta 5
KLHL2 kelch-like family member 2
KRT13 keratin 13, type I
LIMCH1 LIM and calponin homology domains 1
LIN7A lin-7 homolog A (C. elegans)
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MTCL1 microtubule crosslinking factor 1
NAAA N-acylethanolamine acid amidase
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NCAM2 neural cell adhesion molecule 2
NDRG1 N-myc downstream regulated 1
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NEBL nebulette
NUP50 nucleoporin 50kDa
OSGIN1 oxidative stress induced growth inhibitor 1
PBX2 pre-B-cell leukemia homeobox 2
PCGF2 polycomb group ring finger 2
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4
PLK4 polo-like kinase 4
POLD2 polymerase (DNA directed), delta 2, accessory subunit
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PSD4 pleckstrin and Sec7 domain containing 4
PSPH phosphoserine phosphatase
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RANBP3 RAN binding protein 3
RBBP9 retinoblastoma binding protein 9
RECQL5 RecQ protein-like 5
RIN3 Ras and Rab interactor 3
RIOK3 RIO kinase 3
RNF24 ring finger protein 24
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RPL37A ribosomal protein L37a
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RRP1B ribosomal RNA processing 1B
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SIX1 SIX homeobox 1
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
ST20 suppressor of tumorigenicity 20
STRN striatin, calmodulin binding protein
SUGP1 SURP and G patch domain containing 1
TBL1X transducin (beta)-like 1X-linked
TM2D1 TM2 domain containing 1
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TTLL3 tubulin tyrosine ligase-like family member 3
TWF1 twinfilin actin binding protein 1
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
ZNF227 zinc finger protein 227
ZNF253 zinc finger protein 253
ZNF322P1 zinc finger protein 322 pseudogene 1
ZNF408 zinc finger protein 408
ZNF573 zinc finger protein 573
ZNF589 zinc finger protein 589
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACTL8 actin-like 8
ARMC6 armadillo repeat containing 6
ASPHD1 aspartate beta-hydroxylase domain containing 1
BCOR BCL6 corepressor
BFSP1 beaded filament structural protein 1, filensin
BTBD2 BTB (POZ) domain containing 2
C21ORF91 chromosome 21 open reading frame 91
C5AR2 complement component 5a receptor 2
CAPN15 calpain 15
CCDC25 coiled-coil domain containing 25
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CENPO centromere protein O
COQ6 coenzyme Q6 monooxygenase
CORT cortistatin
CPPED1 calcineurin-like phosphoesterase domain containing 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DMTN dematin actin binding protein
DSE dermatan sulfate epimerase
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
EGFL7 EGF-like-domain, multiple 7
EPN2 epsin 2
FAN1 FANCD2/FANCI-associated nuclease 1
FOXC1 forkhead box C1
FOXD1 forkhead box D1
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GAB2 GRB2-associated binding protein 2
HDAC5 histone deacetylase 5
HOOK1 hook microtubule-tethering protein 1
HOXC8 homeobox C8
HPSE heparanase
INF2 inverted formin, FH2 and WH2 domain containing
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KIAA0319L KIAA0319-like
KIAA0894 KIAA0894 protein
KLHL26 kelch-like family member 26
KRT15 keratin 15, type I
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LIME1 Lck interacting transmembrane adaptor 1
LIN7B lin-7 homolog B (C. elegans)
LOC257152 uncharacterized LOC257152
LY6D lymphocyte antigen 6 complex, locus D
MAP9 microtubule-associated protein 9
MTSS1L metastasis suppressor 1-like
NAG18 NAG18 mRNA
NPIPB15 nuclear pore complex interacting protein family, member B15
NT5DC3 5'-nucleotidase domain containing 3
PCDHB13 protocadherin beta 13
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PTPRU protein tyrosine phosphatase, receptor type, U
PTTG3P pituitary tumor-transforming 3, pseudogene
RAD54L2 RAD54-like 2 (S. cerevisiae)
RHOBTB2 Rho-related BTB domain containing 2
RLN2 relaxin 2
RNF25 ring finger protein 25
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SAMD9 sterile alpha motif domain containing 9
SCML2 sex comb on midleg-like 2 (Drosophila)
SCN1B sodium channel, voltage gated, type I beta subunit
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
STAG3 stromal antigen 3
STIM1 stromal interaction molecule 1
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TCHH trichohyalin
TEAD3 TEA domain family member 3
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TH tyrosine hydroxylase
TIGD6 tigger transposable element derived 6
TMC5 transmembrane channel-like 5
TTC33 tetratricopeptide repeat domain 33
TUBA3D tubulin, alpha 3d
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBE2W ubiquitin-conjugating enzyme E2W (putative)
UBXN6 UBX domain protein 6
USP20 ubiquitin specific peptidase 20
WDR91 WD repeat domain 91
XAB2 XPA binding protein 2
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF141 zinc finger protein 141
ZNF180 zinc finger protein 180
ZNF668 zinc finger protein 668
ZNF675 zinc finger protein 675
ZNF8 zinc finger protein 8