5152487-896 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the 5152487-896 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM2 ADAM metallopeptidase domain 2
AKT2 v-akt murine thymoma viral oncogene homolog 2
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ATP11A ATPase, class VI, type 11A
ATP7A ATPase, Cu++ transporting, alpha polypeptide
BTN3A3 butyrophilin, subfamily 3, member A3
CA4 carbonic anhydrase IV
CACYBP calcyclin binding protein
CALR calreticulin
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDK13 cyclin-dependent kinase 13
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3
CHRM3 cholinergic receptor, muscarinic 3
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
COL1A1 collagen, type I, alpha 1
COL5A1 collagen, type V, alpha 1
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CSNK1G1 casein kinase 1, gamma 1
CST6 cystatin E/M
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DLK1 delta-like 1 homolog (Drosophila)
DOK4 docking protein 4
DPYS dihydropyrimidinase
DPYSL4 dihydropyrimidinase-like 4
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPHB4 EPH receptor B4
EYA3 EYA transcriptional coactivator and phosphatase 3
FBXL2 F-box and leucine-rich repeat protein 2
FBXO2 F-box protein 2
FCMR Fc fragment of IgM receptor
FGF6 fibroblast growth factor 6
FNDC3A fibronectin type III domain containing 3A
FOXL1 forkhead box L1
FOXP3 forkhead box P3
GIF gastric intrinsic factor (vitamin B synthesis)
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPATCH2L G patch domain containing 2-like
GSK3A glycogen synthase kinase 3 alpha
GSPT1 G1 to S phase transition 1
HAMP hepcidin antimicrobial peptide
HCG4 HLA complex group 4 (non-protein coding)
HFE hemochromatosis
HIST1H3B histone cluster 1, H3b
HLA-G major histocompatibility complex, class I, G
HOMER3 homer scaffolding protein 3
HSPB11 heat shock protein family B (small), member 11
HSPB6 heat shock protein, alpha-crystallin-related, B6
IFI16 interferon, gamma-inducible protein 16
ITFG2 integrin alpha FG-GAP repeat containing 2
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIAA1107 KIAA1107
KREMEN2 kringle containing transmembrane protein 2
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LIN7A lin-7 homolog A (C. elegans)
LPAR4 lysophosphatidic acid receptor 4
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP4 microtubule-associated protein 4
METTL7A methyltransferase like 7A
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
NPFFR1 neuropeptide FF receptor 1
NUMA1 nuclear mitotic apparatus protein 1
OSGIN1 oxidative stress induced growth inhibitor 1
PACS1 phosphofurin acidic cluster sorting protein 1
PDLIM5 PDZ and LIM domain 5
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PITX2 paired-like homeodomain 2
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLK4 polo-like kinase 4
PRKD3 protein kinase D3
PRLR prolactin receptor
PSEN2 presenilin 2
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RIN3 Ras and Rab interactor 3
RNF24 ring finger protein 24
SCN2B sodium channel, voltage gated, type II beta subunit
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SOCS1 suppressor of cytokine signaling 1
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TBC1D5 TBC1 domain family, member 5
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TOX3 TOX high mobility group box family member 3
TSR3 TSR3, 20S rRNA accumulation, homolog (S. cerevisiae)
TUBA3C tubulin, alpha 3c
TUBB2B tubulin, beta 2B class IIb
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
VIM vimentin
ZC3H7B zinc finger CCCH-type containing 7B
ZNF224 zinc finger protein 224
ZNF442 zinc finger protein 442
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
ACVR2B activin A receptor, type IIB
ADGRE5 adhesion G protein-coupled receptor E5
AFF4 AF4/FMR2 family, member 4
ANKRD36B ankyrin repeat domain 36B
ATP13A2 ATPase type 13A2
BHLHB9 basic helix-loop-helix domain containing, class B, 9
BPGM 2,3-bisphosphoglycerate mutase
C11ORF68 chromosome 11 open reading frame 68
C14ORF93 chromosome 14 open reading frame 93
CBX7 chromobox homolog 7
CCDC25 coiled-coil domain containing 25
CFD complement factor D (adipsin)
CHKB choline kinase beta
CLCF1 cardiotrophin-like cytokine factor 1
CSAD cysteine sulfinic acid decarboxylase
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DMTN dematin actin binding protein
ELOVL4 ELOVL fatty acid elongase 4
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ETAA1 Ewing tumor-associated antigen 1
FAM114A2 family with sequence similarity 114, member A2
FAM206A family with sequence similarity 206, member A
FAM222B family with sequence similarity 222, member B
FLJ42627 uncharacterized LOC645644
GALT galactose-1-phosphate uridylyltransferase
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPR87 G protein-coupled receptor 87
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
GUSBP3 glucuronidase, beta pseudogene 3
HIRA histone cell cycle regulator
IMPACT impact RWD domain protein
IPO13 importin 13
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KIAA0141 KIAA0141
LAMB1 laminin, beta 1
LINC00115 long intergenic non-protein coding RNA 115
LINS lines homolog (Drosophila)
LOC100272216 uncharacterized LOC100272216
MAST3 microtubule associated serine/threonine kinase 3
MB myoglobin
MORC3 MORC family CW-type zinc finger 3
MSANTD2 Myb/SANT-like DNA-binding domain containing 2
NAG18 NAG18 mRNA
NDE1 nudE neurodevelopment protein 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NLRX1 NLR family member X1
OFD1 oral-facial-digital syndrome 1
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PCBP4 poly(rC) binding protein 4
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLD3 phospholipase D family, member 3
POLH polymerase (DNA directed), eta
POMT1 protein-O-mannosyltransferase 1
PTTG3P pituitary tumor-transforming 3, pseudogene
RASAL1 RAS protein activator like 1 (GAP1 like)
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBM41 RNA binding motif protein 41
REPS2 RALBP1 associated Eps domain containing 2
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
RWDD3 RWD domain containing 3
SCUBE2 signal peptide, CUB domain, EGF-like 2
SH2B3 SH2B adaptor protein 3
SLC12A8 solute carrier family 12, member 8
SLC12A9 solute carrier family 12, member 9
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SOX12 SRY (sex determining region Y)-box 12
STX5 syntaxin 5
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYCP2 synaptonemal complex protein 2
TEAD3 TEA domain family member 3
TMEM115 transmembrane protein 115
TMEM254 transmembrane protein 254
TRAF2 TNF receptor-associated factor 2
TRIM52 tripartite motif containing 52
TSPAN1 tetraspanin 1
UBQLN4 ubiquilin 4
UNC119 unc-119 homolog (C. elegans)
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae)
WDR91 WD repeat domain 91
ZBTB48 zinc finger and BTB domain containing 48
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF33B zinc finger protein 33B
ZNF428 zinc finger protein 428
ZNF675 zinc finger protein 675
ZNF778 zinc finger protein 778
ZNF85 zinc finger protein 85