5155877-6544 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the 5155877-6544 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADGRL1 adhesion G protein-coupled receptor L1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ANGPTL4 angiopoietin-like 4
ANXA10 annexin A10
AP3B1 adaptor-related protein complex 3, beta 1 subunit
ARRB2 arrestin, beta 2
ASMTL acetylserotonin O-methyltransferase-like
AURKC aurora kinase C
BAHD1 bromo adjacent homology domain containing 1
C1QTNF1 C1q and tumor necrosis factor related protein 1
CD79B CD79b molecule, immunoglobulin-associated beta
CDH7 cadherin 7, type 2
CDON cell adhesion associated, oncogene regulated
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CRYL1 crystallin, lambda 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DDIT3 DNA-damage-inducible transcript 3
DLK2 delta-like 2 homolog (Drosophila)
DSC2 desmocollin 2
ELF4 E74-like factor 4 (ets domain transcription factor)
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
ERC1 ELKS/RAB6-interacting/CAST family member 1
EVI5 ecotropic viral integration site 5
F11R F11 receptor
FABP4 fatty acid binding protein 4, adipocyte
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GABARAPL1 GABA(A) receptor-associated protein like 1
GAREM GRB2 associated, regulator of MAPK1
GK3P glycerol kinase 3 pseudogene
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GPX2 glutathione peroxidase 2
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HOXC5 homeobox C5
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
JMJD6 jumonji domain containing 6
KAZN kazrin, periplakin interacting protein
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12
KDM7A lysine (K)-specific demethylase 7A
KLF3 Kruppel-like factor 3 (basic)
LAMA4 laminin, alpha 4
LOC81691 exonuclease NEF-sp
LPIN1 lipin 1
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MAX MYC associated factor X
MCTP2 multiple C2 domains, transmembrane 2
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
MXD4 MAX dimerization protein 4
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NXPE3 neurexophilin and PC-esterase domain family, member 3
ODF2 outer dense fiber of sperm tails 2
OSGIN1 oxidative stress induced growth inhibitor 1
PACS1 phosphofurin acidic cluster sorting protein 1
PDPN podoplanin
PIDD1 p53-induced death domain protein 1
PLIN2 perilipin 2
PTGES prostaglandin E synthase
QKI QKI, KH domain containing, RNA binding
RAB4B RAB4B, member RAS oncogene family
REPS1 RALBP1 associated Eps domain containing 1
RSL1D1 ribosomal L1 domain containing 1
RUNX1 runt-related transcription factor 1
S100A3 S100 calcium binding protein A3
SIPA1L3 signal-induced proliferation-associated 1 like 3
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLMO1 slowmo homolog 1 (Drosophila)
SORBS1 sorbin and SH3 domain containing 1
SORBS3 sorbin and SH3 domain containing 3
SPTBN1 spectrin, beta, non-erythrocytic 1
SQSTM1 sequestosome 1
STC2 stanniocalcin 2
STK11 serine/threonine kinase 11
STYK1 serine/threonine/tyrosine kinase 1
TBXAS1 thromboxane A synthase 1 (platelet)
THOC5 THO complex 5
TMEM57 transmembrane protein 57
TNK2 tyrosine kinase, non-receptor, 2
TRAF3IP2 TRAF3 interacting protein 2
TRIM16 tripartite motif containing 16
TTC3 tetratricopeptide repeat domain 3
TTC30A tetratricopeptide repeat domain 30A
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative)
UHRF1BP1L UHRF1 binding protein 1-like
WSB1 WD repeat and SOCS box containing 1
ZBTB43 zinc finger and BTB domain containing 43
ZFP36 ZFP36 ring finger protein
ZNF292 zinc finger protein 292
ZNF614 zinc finger protein 614

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABI3BP ABI family, member 3 (NESH) binding protein
AFAP1 actin filament associated protein 1
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ARMCX4 armadillo repeat containing, X-linked 4
BCL9 B-cell CLL/lymphoma 9
BEX1 brain expressed, X-linked 1
BMP15 bone morphogenetic protein 15
C1ORF56 chromosome 1 open reading frame 56
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CCDC9 coiled-coil domain containing 9
CFAP69 cilia and flagella associated protein 69
CLEC16A C-type lectin domain family 16, member A
CNTNAP1 contactin associated protein 1
COBL cordon-bleu WH2 repeat protein
COL9A3 collagen, type IX, alpha 3
CORO7 coronin 7
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CTC1 CTS telomere maintenance complex component 1
DCLRE1A DNA cross-link repair 1A
DDN dendrin
DNM3 dynamin 3
E2F8 E2F transcription factor 8
EGF epidermal growth factor
EIF5A2 eukaryotic translation initiation factor 5A2
FRS3 fibroblast growth factor receptor substrate 3
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GDAP1 ganglioside induced differentiation associated protein 1
GMEB1 glucocorticoid modulatory element binding protein 1
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GRPR gastrin-releasing peptide receptor
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GUSBP3 glucuronidase, beta pseudogene 3
H1F0 H1 histone family, member 0
HHAT hedgehog acyltransferase
HIST1H3G histone cluster 1, H3g
HOXB9 homeobox B9
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IMPACT impact RWD domain protein
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KCTD15 potassium channel tetramerization domain containing 15
KIRREL kin of IRRE like (Drosophila)
KLK7 kallikrein-related peptidase 7
KPTN kaptin (actin binding protein)
KRT4 keratin 4, type II
LIPG lipase, endothelial
LMNB1 lamin B1
LOC257152 uncharacterized LOC257152
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LYPD1 LY6/PLAUR domain containing 1
MAGEF1 melanoma antigen family F1
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MMP9 matrix metallopeptidase 9
MN1 meningioma (disrupted in balanced translocation) 1
MNX1 motor neuron and pancreas homeobox 1
MT1M metallothionein 1M
MYF5 myogenic factor 5
NACA2 nascent polypeptide-associated complex alpha subunit 2
NAT6 N-acetyltransferase 6 (GCN5-related)
NME5 NME/NM23 family member 5
NT5C 5', 3'-nucleotidase, cytosolic
ONECUT2 one cut homeobox 2
OVGP1 oviductal glycoprotein 1, 120kDa
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PALM paralemmin
PALMD palmdelphin
PAQR6 progestin and adipoQ receptor family member VI
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PRDM1 PR domain containing 1, with ZNF domain
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
RAB3D RAB3D, member RAS oncogene family
RUNDC3B RUN domain containing 3B
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SPIDR scaffolding protein involved in DNA repair
SRD5A3 steroid 5 alpha-reductase 3
STAG3 stromal antigen 3
STK16 serine/threonine kinase 16
TBKBP1 TBK1 binding protein 1
TCTN2 tectonic family member 2
TESK2 testis-specific kinase 2
TMC7 transmembrane channel-like 7
TRABD TraB domain containing
TSPAN1 tetraspanin 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VGF VGF nerve growth factor inducible
WNT10B wingless-type MMTV integration site family, member 10B
ZFP30 ZFP30 zinc finger protein
ZNF219 zinc finger protein 219
ZNF230 zinc finger protein 230
ZNF253 zinc finger protein 253
ZNF254 zinc finger protein 254
ZNF350 zinc finger protein 350
ZNF747 zinc finger protein 747