5155877-6549 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the 5155877-6549 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
ATAD5 ATPase family, AAA domain containing 5
ATF3 activating transcription factor 3
BIN1 bridging integrator 1
BMP7 bone morphogenetic protein 7
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
CBR3 carbonyl reductase 3
CBX8 chromobox homolog 8
CIAO1 cytosolic iron-sulfur assembly component 1
CLGN calmegin
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
COBLL1 cordon-bleu WH2 repeat protein-like 1
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DDIT3 DNA-damage-inducible transcript 3
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DOLPP1 dolichyldiphosphatase 1
DVL3 dishevelled segment polarity protein 3
EFNA3 ephrin-A3
ENO2 enolase 2 (gamma, neuronal)
EPOR erythropoietin receptor
ERCC5 excision repair cross-complementation group 5
FAM188A family with sequence similarity 188, member A
FEM1C fem-1 homolog c (C. elegans)
FGF23 fibroblast growth factor 23
FOSL1 FOS-like antigen 1
FOSL2 FOS-like antigen 2
FTH1 ferritin, heavy polypeptide 1
FXR2 fragile X mental retardation, autosomal homolog 2
GCLM glutamate-cysteine ligase, modifier subunit
GJA4 gap junction protein, alpha 4, 37kDa
GPR137 G protein-coupled receptor 137
HMOX1 heme oxygenase 1
HRK harakiri, BCL2 interacting protein
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL1R1 interleukin 1 receptor, type I
IL6R interleukin 6 receptor
JAG1 jagged 1
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KCTD7 potassium channel tetramerization domain containing 7
KDM6B lysine (K)-specific demethylase 6B
KIAA0895 KIAA0895
KIF5C kinesin family member 5C
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LYST lysosomal trafficking regulator
MAP2K7 mitogen-activated protein kinase kinase 7
MAPK14 mitogen-activated protein kinase 14
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MID1 midline 1
MIR22HG MIR22 host gene
MKRN2 makorin ring finger protein 2
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MTM1 myotubularin 1
N4BP2L2 NEDD4 binding protein 2-like 2
NME5 NME/NM23 family member 5
NUPR1 nuclear protein, transcriptional regulator, 1
OSGIN1 oxidative stress induced growth inhibitor 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PILRA paired immunoglobin-like type 2 receptor alpha
PLSCR3 phospholipid scramblase 3
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
POPDC3 popeye domain containing 3
REPS1 RALBP1 associated Eps domain containing 1
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
SH3BP2 SH3-domain binding protein 2
SIRPA signal-regulatory protein alpha
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC25A40 solute carrier family 25, member 40
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMG5 SMG5 nonsense mediated mRNA decay factor
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SS18 synovial sarcoma translocation, chromosome 18
SYNM synemin, intermediate filament protein
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TM6SF1 transmembrane 6 superfamily member 1
TMCC2 transmembrane and coiled-coil domain family 2
TMF1 TATA element modulatory factor 1
TMSB15A thymosin beta 15a
TPK1 thiamin pyrophosphokinase 1
TRIM16 tripartite motif containing 16
TROVE2 TROVE domain family, member 2
TUBA4A tubulin, alpha 4a
TXNRD1 thioredoxin reductase 1
UBQLN4 ubiquilin 4
USB1 U6 snRNA biogenesis 1
WDTC1 WD and tetratricopeptide repeats 1
ZNF34 zinc finger protein 34
ZNF37BP zinc finger protein 37B, pseudogene
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
AHR aryl hydrocarbon receptor
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASIC3 acid sensing (proton gated) ion channel 3
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATAT1 alpha tubulin acetyltransferase 1
BCAS1 breast carcinoma amplified sequence 1
BMP5 bone morphogenetic protein 5
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C1ORF56 chromosome 1 open reading frame 56
C9ORF40 chromosome 9 open reading frame 40
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CDADC1 cytidine and dCMP deaminase domain containing 1
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CFD complement factor D (adipsin)
CLCN6 chloride channel, voltage-sensitive 6
CLDND1 claudin domain containing 1
CLK2 CDC-like kinase 2
CLSTN2 calsyntenin 2
CNGB3 cyclic nucleotide gated channel beta 3
CTC1 CTS telomere maintenance complex component 1
DGAT1 diacylglycerol O-acyltransferase 1
DIXDC1 DIX domain containing 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DSCAM Down syndrome cell adhesion molecule
DTX4 deltex 4, E3 ubiquitin ligase
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ELOVL4 ELOVL fatty acid elongase 4
EPHA4 EPH receptor A4
F2R coagulation factor II (thrombin) receptor
FBRS fibrosin
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GPHN gephyrin
H1F0 H1 histone family, member 0
HIST1H1D histone cluster 1, H1d
HLA-J major histocompatibility complex, class I, J (pseudogene)
HOXC13 homeobox C13
HOXC8 homeobox C8
HPN hepsin
IFI27 interferon, alpha-inducible protein 27
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KIAA0125 KIAA0125
KIAA0754 KIAA0754
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LOC100287590 uncharacterized LOC100287590
LOC642236 FSHD region gene 1 pseudogene
LY6D lymphocyte antigen 6 complex, locus D
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAST3 microtubule associated serine/threonine kinase 3
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
NPY5R neuropeptide Y receptor Y5
NT5DC3 5'-nucleotidase domain containing 3
NXF2 nuclear RNA export factor 2
OVGP1 oviductal glycoprotein 1, 120kDa
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PEAK1 pseudopodium-enriched atypical kinase 1
PECR peroxisomal trans-2-enoyl-CoA reductase
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLA2G3 phospholipase A2, group III
PLD2 phospholipase D2
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
PP14571 uncharacterized LOC100130449
PRKCD protein kinase C, delta
PRR15L proline rich 15-like
PTK6 protein tyrosine kinase 6
QPCTL glutaminyl-peptide cyclotransferase-like
RANGRF RAN guanine nucleotide release factor
RASA2 RAS p21 protein activator 2
RASAL1 RAS protein activator like 1 (GAP1 like)
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RGS16 regulator of G-protein signaling 16
RNF2 ring finger protein 2
RPS4Y1 ribosomal protein S4, Y-linked 1
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SGK1 serum/glucocorticoid regulated kinase 1
SH3GLB2 SH3-domain GRB2-like endophilin B2
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
SPATA7 spermatogenesis associated 7
SPINK4 serine peptidase inhibitor, Kazal type 4
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBC1D17 TBC1 domain family, member 17
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TEAD3 TEA domain family member 3
TMC5 transmembrane channel-like 5
TSC22D4 TSC22 domain family, member 4
TSPAN1 tetraspanin 1
TTPAL tocopherol (alpha) transfer protein-like
USP27X ubiquitin specific peptidase 27, X-linked
VAX2 ventral anterior homeobox 2
ZNF204P zinc finger protein 204, pseudogene
ZNF253 zinc finger protein 253