5162773-892 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the 5162773-892 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACVR1B activin A receptor, type IB
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
ANKRD6 ankyrin repeat domain 6
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APOM apolipoprotein M
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ATRX alpha thalassemia/mental retardation syndrome X-linked
AURKA aurora kinase A
B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
BCORL1 BCL6 corepressor-like 1
BHLHE40 basic helix-loop-helix family, member e40
BICD1 bicaudal D homolog 1 (Drosophila)
CACYBP calcyclin binding protein
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CDC73 cell division cycle 73
COL1A1 collagen, type I, alpha 1
COMT catechol-O-methyltransferase
CSPP1 centrosome and spindle pole associated protein 1
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DPYSL4 dihydropyrimidinase-like 4
DTNA dystrobrevin, alpha
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ENPEP glutamyl aminopeptidase (aminopeptidase A)
EPHB2 EPH receptor B2
EPN3 epsin 3
FAM189A2 family with sequence similarity 189, member A2
FAS Fas cell surface death receptor
FGF23 fibroblast growth factor 23
FNDC3A fibronectin type III domain containing 3A
FRS2 fibroblast growth factor receptor substrate 2
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNAS GNAS complex locus
GPATCH2L G patch domain containing 2-like
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
GPR27 G protein-coupled receptor 27
GRM8 glutamate receptor, metabotropic 8
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
INADL InaD-like (Drosophila)
ITGB4 integrin, beta 4
KIF25 kinesin family member 25
KLF4 Kruppel-like factor 4 (gut)
KLHL21 kelch-like family member 21
KPTN kaptin (actin binding protein)
LIN7A lin-7 homolog A (C. elegans)
LINC00339 long intergenic non-protein coding RNA 339
LPP LIM domain containing preferred translocation partner in lipoma
LYRM9 LYR motif containing 9
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAPRE1 microtubule-associated protein, RP/EB family, member 1
MDM4 MDM4, p53 regulator
MED14 mediator complex subunit 14
METTL16 methyltransferase like 16
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NBPF10 neuroblastoma breakpoint family, member 10
NCOA2 nuclear receptor coactivator 2
NEBL nebulette
NEK2 NIMA-related kinase 2
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
OTUD4 OTU deubiquitinase 4
PARD6B par-6 family cell polarity regulator beta
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDB1 pleckstrin homology-like domain, family B, member 1
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLK4 polo-like kinase 4
PRAF2 PRA1 domain family, member 2
PTPRA protein tyrosine phosphatase, receptor type, A
RBBP9 retinoblastoma binding protein 9
REEP2 receptor accessory protein 2
RNF126P1 ring finger protein 126 pseudogene 1
RPS28 ribosomal protein S28
RRBP1 ribosome binding protein 1
RUFY2 RUN and FYVE domain containing 2
SCAMP1 secretory carrier membrane protein 1
SCCPDH saccharopine dehydrogenase (putative)
SHANK2 SH3 and multiple ankyrin repeat domains 2
SIDT2 SID1 transmembrane family, member 2
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SORT1 sortilin 1
SSPN sarcospan
STAT1 signal transducer and activator of transcription 1, 91kDa
STX16 syntaxin 16
THBS3 thrombospondin 3
TMSB15A thymosin beta 15a
VAX2 ventral anterior homeobox 2
WDR62 WD repeat domain 62
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZMYM2 zinc finger, MYM-type 2
ZNF350 zinc finger protein 350
ZNF43 zinc finger protein 43
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ACSF2 acyl-CoA synthetase family member 2
AKIP1 A kinase (PRKA) interacting protein 1
ALPK1 alpha-kinase 1
AMPD2 adenosine monophosphate deaminase 2
ANKRD40 ankyrin repeat domain 40
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARID4A AT rich interactive domain 4A (RBP1-like)
ARMC6 armadillo repeat containing 6
ASPHD1 aspartate beta-hydroxylase domain containing 1
BAHCC1 BAH domain and coiled-coil containing 1
BBC3 BCL2 binding component 3
BFSP1 beaded filament structural protein 1, filensin
BTBD2 BTB (POZ) domain containing 2
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
C22ORF29 chromosome 22 open reading frame 29
C22ORF46 chromosome 22 open reading frame 46
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CLCF1 cardiotrophin-like cytokine factor 1
CLSPN claspin
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DND1 DND microRNA-mediated repression inhibitor 1
DSE dermatan sulfate epimerase
DSPP dentin sialophosphoprotein
EFCAB2 EF-hand calcium binding domain 2
FAM188A family with sequence similarity 188, member A
FBXW12 F-box and WD repeat domain containing 12
FCHSD2 FCH and double SH3 domains 2
FGGY FGGY carbohydrate kinase domain containing
FLJ22184
FPGS folylpolyglutamate synthase
GUSBP3 glucuronidase, beta pseudogene 3
HOOK1 hook microtubule-tethering protein 1
IFT140 intraflagellar transport 140
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KDM5C lysine (K)-specific demethylase 5C
KDM8 lysine (K)-specific demethylase 8
KIAA0125 KIAA0125
KIAA0319L KIAA0319-like
LIME1 Lck interacting transmembrane adaptor 1
LIN7B lin-7 homolog B (C. elegans)
LPPR2 lipid phosphate phosphatase-related protein type 2
LRRC37A2 leucine rich repeat containing 37, member A2
LY6D lymphocyte antigen 6 complex, locus D
MAP1S microtubule-associated protein 1S
MCOLN1 mucolipin 1
MED15 mediator complex subunit 15
MED9 mediator complex subunit 9
METRN meteorin, glial cell differentiation regulator
MTSS1L metastasis suppressor 1-like
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NAG18 NAG18 mRNA
NDE1 nudE neurodevelopment protein 1
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
OSMR oncostatin M receptor
PCBP4 poly(rC) binding protein 4
PHACTR4 phosphatase and actin regulator 4
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PPT2 palmitoyl-protein thioesterase 2
PSKH1 protein serine kinase H1
RAB33B RAB33B, member RAS oncogene family
RBL1 retinoblastoma-like 1
RHOBTB2 Rho-related BTB domain containing 2
RPL23AP7 ribosomal protein L23a pseudogene 7
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
SCN1B sodium channel, voltage gated, type I beta subunit
SCUBE2 signal peptide, CUB domain, EGF-like 2
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SKA1 spindle and kinetochore associated complex subunit 1
SLC12A8 solute carrier family 12, member 8
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
STX5 syntaxin 5
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TARP TCR gamma alternate reading frame protein
TICAM1 toll-like receptor adaptor molecule 1
TM7SF3 transmembrane 7 superfamily member 3
TMC5 transmembrane channel-like 5
TMPRSS4 transmembrane protease, serine 4
TRIM5 tripartite motif containing 5
TSSC4 tumor suppressing subtransferable candidate 4
TTLL1 tubulin tyrosine ligase-like family member 1
USB1 U6 snRNA biogenesis 1
USP36 ubiquitin specific peptidase 36
XAB2 XPA binding protein 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
XYLT2 xylosyltransferase II
ZFP30 ZFP30 zinc finger protein
ZNF428 zinc finger protein 428
ZNF432 zinc finger protein 432
ZNF516 zinc finger protein 516
ZNF580 zinc finger protein 580
ZNF665 zinc finger protein 665
ZNF675 zinc finger protein 675