5182598-868 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the 5182598-868 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABHD4 abhydrolase domain containing 4
ADAM17 ADAM metallopeptidase domain 17
ADAM2 ADAM metallopeptidase domain 2
ADCK2 aarF domain containing kinase 2
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ARTN artemin
ATF3 activating transcription factor 3
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
CACYBP calcyclin binding protein
CBR3 carbonyl reductase 3
CDK13 cyclin-dependent kinase 13
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
CRELD1 cysteine-rich with EGF-like domains 1
CTTN cortactin
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DIO2 deiodinase, iodothyronine, type II
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DND1 DND microRNA-mediated repression inhibitor 1
DOHH deoxyhypusine hydroxylase/monooxygenase
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EDRF1 erythroid differentiation regulatory factor 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FECH ferrochelatase
FLJ42627 uncharacterized LOC645644
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GSPT1 G1 to S phase transition 1
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
HIPK2 homeodomain interacting protein kinase 2
HIST1H3B histone cluster 1, H3b
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
INHBE inhibin, beta E
JUN jun proto-oncogene
KIAA0894 KIAA0894 protein
KLF9 Kruppel-like factor 9
KLHL24 kelch-like family member 24
LDLR low density lipoprotein receptor
LLGL1 lethal giant larvae homolog 1 (Drosophila)
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MAP1B microtubule-associated protein 1B
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED9 mediator complex subunit 9
MIR22HG MIR22 host gene
MYO10 myosin X
N4BP2L2 NEDD4 binding protein 2-like 2
NOP16 NOP16 nucleolar protein
NRP1 neuropilin 1
OGFR opioid growth factor receptor
OSGIN1 oxidative stress induced growth inhibitor 1
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PAPOLA poly(A) polymerase alpha
PDE12 phosphodiesterase 12
PDLIM5 PDZ and LIM domain 5
PGAP3 post-GPI attachment to proteins 3
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLD2 phospholipase D2
PLXDC1 plexin domain containing 1
PPARD peroxisome proliferator-activated receptor delta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PSPH phosphoserine phosphatase
REPS1 RALBP1 associated Eps domain containing 1
RGCC regulator of cell cycle
SBNO1 strawberry notch homolog 1 (Drosophila)
SCAI suppressor of cancer cell invasion
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SLC12A8 solute carrier family 12, member 8
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
STYK1 serine/threonine/tyrosine kinase 1
SYNM synemin, intermediate filament protein
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRAK1 trafficking protein, kinesin binding 1
TRIB3 tribbles pseudokinase 3
TRIM66 tripartite motif containing 66
TXNRD1 thioredoxin reductase 1
UNKL unkempt family zinc finger-like
VLDLR very low density lipoprotein receptor
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
ZBTB43 zinc finger and BTB domain containing 43
ZNF227 zinc finger protein 227
ZNF350 zinc finger protein 350
ZNF770 zinc finger protein 770

decreased expression

Symbol Name
ABHD10 abhydrolase domain containing 10
ADGRA3 adhesion G protein-coupled receptor A3
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AIM1 absent in melanoma 1
ARHGAP12 Rho GTPase activating protein 12
ARID5B AT rich interactive domain 5B (MRF1-like)
ARMCX1 armadillo repeat containing, X-linked 1
ATP7B ATPase, Cu++ transporting, beta polypeptide
B3GNT1
BAHCC1 BAH domain and coiled-coil containing 1
BAMBI BMP and activin membrane-bound inhibitor
BEX4 brain expressed, X-linked 4
C1ORF106 chromosome 1 open reading frame 106
C3ORF52 chromosome 3 open reading frame 52
C4ORF19 chromosome 4 open reading frame 19
C4ORF27 chromosome 4 open reading frame 27
C6ORF47 chromosome 6 open reading frame 47
CARD8 caspase recruitment domain family, member 8
CEP97 centrosomal protein 97kDa
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLDN9 claudin 9
CLEC16A C-type lectin domain family 16, member A
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
DEPDC1 DEP domain containing 1
EFNB2 ephrin-B2
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
EPN3 epsin 3
EXTL2 exostosin-like glycosyltransferase 2
EYA2 EYA transcriptional coactivator and phosphatase 2
FAM63A family with sequence similarity 63, member A
FBXL2 F-box and leucine-rich repeat protein 2
GSTM1 glutathione S-transferase mu 1
HAUS6 HAUS augmin-like complex, subunit 6
HOXA5 homeobox A5
HOXC6 homeobox C6
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFT140 intraflagellar transport 140
INHBB inhibin, beta B
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1
KLHL2 kelch-like family member 2
KRT15 keratin 15, type I
LIMA1 LIM domain and actin binding 1
LY6G5C lymphocyte antigen 6 complex, locus G5C
LYPD3 LY6/PLAUR domain containing 3
MANEA mannosidase, endo-alpha
MANSC1 MANSC domain containing 1
MATK megakaryocyte-associated tyrosine kinase
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha)
MED23 mediator complex subunit 23
MMD monocyte to macrophage differentiation-associated
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MNS1 meiosis-specific nuclear structural 1
MPI mannose phosphate isomerase
MT1HL1 metallothionein 1H-like 1
NAV2 neuron navigator 2
NMI N-myc (and STAT) interactor
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
NTHL1 nth endonuclease III-like 1 (E. coli)
NUP62CL nucleoporin 62kDa C-terminal like
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PARD6A par-6 family cell polarity regulator alpha
PCOLCE2 procollagen C-endopeptidase enhancer 2
PEX11A peroxisomal biogenesis factor 11 alpha
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PLD3 phospholipase D family, member 3
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRICKLE3 prickle homolog 3 (Drosophila)
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRR15L proline rich 15-like
RIC8B RIC8 guanine nucleotide exchange factor B
SAV1 salvador family WW domain containing protein 1
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SGK1 serum/glucocorticoid regulated kinase 1
SGMS1 sphingomyelin synthase 1
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC31A2 solute carrier family 31 (copper transporter), member 2
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SOBP sine oculis binding protein homolog (Drosophila)
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SP140L SP140 nuclear body protein-like
SSFA2 sperm specific antigen 2
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SYNJ2BP synaptojanin 2 binding protein
TESK2 testis-specific kinase 2
TGFB3 transforming growth factor, beta 3
TMEM62 transmembrane protein 62
TNRC6B trinucleotide repeat containing 6B
TNS3 tensin 3
TRAF5 TNF receptor-associated factor 5
TRIM45 tripartite motif containing 45
TRIM52 tripartite motif containing 52
UNC13B unc-13 homolog B (C. elegans)
VAV3 vav 3 guanine nucleotide exchange factor
WDR19 WD repeat domain 19
ZBTB10 zinc finger and BTB domain containing 10
ZNF22 zinc finger protein 22