5186223-885 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the 5186223-885 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
AFAP1 actin filament associated protein 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ANKRD12 ankyrin repeat domain 12
ARID1A AT rich interactive domain 1A (SWI-like)
ASTN2 astrotactin 2
BEGAIN brain-enriched guanylate kinase-associated
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CBX8 chromobox homolog 8
CCPG1 cell cycle progression 1
COL10A1 collagen, type X, alpha 1
COL5A1 collagen, type V, alpha 1
COL9A3 collagen, type IX, alpha 3
COX11 COX11 cytochrome c oxidase copper chaperone
CPD carboxypeptidase D
CTBS chitobiase, di-N-acetyl-
CYHR1 cysteine/histidine-rich 1
DDO D-aspartate oxidase
DGAT1 diacylglycerol O-acyltransferase 1
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DST dystonin
DTNA dystrobrevin, alpha
ERP44 endoplasmic reticulum protein 44
EXOG endo/exonuclease (5'-3'), endonuclease G-like
F3 coagulation factor III (thromboplastin, tissue factor)
FAM107A family with sequence similarity 107, member A
FANCA Fanconi anemia, complementation group A
FBXO2 F-box protein 2
FGFR2 fibroblast growth factor receptor 2
GPR137 G protein-coupled receptor 137
HDAC4 histone deacetylase 4
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HLA-G major histocompatibility complex, class I, G
HSPB11 heat shock protein family B (small), member 11
IGH immunoglobulin heavy locus
ITM2B integral membrane protein 2B
LDHB lactate dehydrogenase B
MANEA mannosidase, endo-alpha
MCL1 myeloid cell leukemia 1
MCPH1 microcephalin 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MFAP3L microfibrillar-associated protein 3-like
MORC2 MORC family CW-type zinc finger 2
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MUC2 mucin 2, oligomeric mucus/gel-forming
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
MYOF myoferlin
NCAPH2 non-SMC condensin II complex, subunit H2
NCOA2 nuclear receptor coactivator 2
NPTX1 neuronal pentraxin I
NUDC nudC nuclear distribution protein
PCDH12 protocadherin 12
PCDH7 protocadherin 7
PCNX pecanex homolog (Drosophila)
PCNXL4 pecanex-like 4 (Drosophila)
PDLIM5 PDZ and LIM domain 5
PRKD3 protein kinase D3
PTPN2 protein tyrosine phosphatase, non-receptor type 2
RAB40A RAB40A, member RAS oncogene family
RAB40C RAB40C, member RAS oncogene family
RIT2 Ras-like without CAAX 2
RNF121 ring finger protein 121
RPS2 ribosomal protein S2
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
RRAGB Ras-related GTP binding B
RUNX1 runt-related transcription factor 1
SAMD4A sterile alpha motif domain containing 4A
SBNO2 strawberry notch homolog 2 (Drosophila)
SCAMP1 secretory carrier membrane protein 1
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC16A4 solute carrier family 16, member 4
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNX13 sorting nexin 13
SORT1 sortilin 1
SPG20 spastic paraplegia 20 (Troyer syndrome)
SPTBN1 spectrin, beta, non-erythrocytic 1
STEAP4 STEAP family member 4
SUGP1 SURP and G patch domain containing 1
SWAP70 SWAP switching B-cell complex 70kDa subunit
TBC1D2 TBC1 domain family, member 2
TBX3 T-box 3
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM209 transmembrane protein 209
TNPO2 transportin 2
TRAIP TRAF interacting protein
TUBB2B tubulin, beta 2B class IIb
USP12 ubiquitin specific peptidase 12
VAV2 vav 2 guanine nucleotide exchange factor
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WWOX WW domain containing oxidoreductase
ZBTB33 zinc finger and BTB domain containing 33
ZFPL1 zinc finger protein-like 1
ZNF223 zinc finger protein 223
ZNF277 zinc finger protein 277
ZNF3 zinc finger protein 3
ZW10 zw10 kinetochore protein

decreased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
ALS2CL ALS2 C-terminal like
ASPHD1 aspartate beta-hydroxylase domain containing 1
C19ORF54 chromosome 19 open reading frame 54
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC88C coiled-coil domain containing 88C
CDKL3 cyclin-dependent kinase-like 3
CENPT centromere protein T
CFD complement factor D (adipsin)
CHKB choline kinase beta
CISH cytokine inducible SH2-containing protein
CRLF1 cytokine receptor-like factor 1
CRYL1 crystallin, lambda 1
CSAD cysteine sulfinic acid decarboxylase
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DHDDS dehydrodolichyl diphosphate synthase
DMTN dematin actin binding protein
DNM1 dynamin 1
DUSP8 dual specificity phosphatase 8
EXO5 exonuclease 5
FAAH fatty acid amide hydrolase
GMIP GEM interacting protein
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GUSBP3 glucuronidase, beta pseudogene 3
HAUS2 HAUS augmin-like complex, subunit 2
HIRA histone cell cycle regulator
HIST1H2BF histone cluster 1, H2bf
HIST1H2BJ histone cluster 1, H2bj
HIST1H3B histone cluster 1, H3b
HOXC8 homeobox C8
HYI hydroxypyruvate isomerase (putative)
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
JMJD4 jumonji domain containing 4
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KIAA0894 KIAA0894 protein
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LOC100272216 uncharacterized LOC100272216
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LPIN2 lipin 2
LY6D lymphocyte antigen 6 complex, locus D
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MAN2C1 mannosidase, alpha, class 2C, member 1
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MRPS18C mitochondrial ribosomal protein S18C
NAG18 NAG18 mRNA
NPIPB15 nuclear pore complex interacting protein family, member B15
OXTR oxytocin receptor
PARD6A par-6 family cell polarity regulator alpha
PCBP4 poly(rC) binding protein 4
PCDHA5 protocadherin alpha 5
PDE12 phosphodiesterase 12
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PLEKHA6 pleckstrin homology domain containing, family A member 6
PRB3 proline-rich protein BstNI subfamily 3
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRPH peripherin
PTPN6 protein tyrosine phosphatase, non-receptor type 6
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RHOBTB2 Rho-related BTB domain containing 2
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF43 ring finger protein 43
SAMD9 sterile alpha motif domain containing 9
SARS2 seryl-tRNA synthetase 2, mitochondrial
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC12A8 solute carrier family 12, member 8
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNHG20 small nucleolar RNA host gene 20
SOWAHC sosondowah ankyrin repeat domain family member C
STAG3L1 stromal antigen 3-like 1 (pseudogene)
SYT17 synaptotagmin XVII
TCHH trichohyalin
TH tyrosine hydroxylase
TIGD6 tigger transposable element derived 6
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIM66 tripartite motif containing 66
TTC33 tetratricopeptide repeat domain 33
UBQLN4 ubiquilin 4
ULBP2 UL16 binding protein 2
USB1 U6 snRNA biogenesis 1
USP27X ubiquitin specific peptidase 27, X-linked
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VEGFC vascular endothelial growth factor C
VGF VGF nerve growth factor inducible
VWA1 von Willebrand factor A domain containing 1
WDR76 WD repeat domain 76
ZBTB48 zinc finger and BTB domain containing 48
ZNF134 zinc finger protein 134
ZNF160 zinc finger protein 160
ZNF34 zinc finger protein 34
ZNF35 zinc finger protein 35
ZNF692 zinc finger protein 692
ZNF76 zinc finger protein 76