5194442-6553 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the 5194442-6553 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABR active BCR-related
ADM adrenomedullin
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BMP4 bone morphogenetic protein 4
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
C1ORF116 chromosome 1 open reading frame 116
CARD8 caspase recruitment domain family, member 8
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDH7 cadherin 7, type 2
CDK13 cyclin-dependent kinase 13
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CHD3 chromodomain helicase DNA binding protein 3
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLCN6 chloride channel, voltage-sensitive 6
CLCN7 chloride channel, voltage-sensitive 7
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CRYBA2 crystallin, beta A2
DENND2A DENN/MADD domain containing 2A
DEPTOR DEP domain containing MTOR-interacting protein
ESRRG estrogen-related receptor gamma
FABP4 fatty acid binding protein 4, adipocyte
FAM174B family with sequence similarity 174, member B
FKBP1B FK506 binding protein 1B, 12.6 kDa
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GCLM glutamate-cysteine ligase, modifier subunit
GEMIN8 gem (nuclear organelle) associated protein 8
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GTPBP4 GTP binding protein 4
HIP1 huntingtin interacting protein 1
HIST1H3G histone cluster 1, H3g
HMOX1 heme oxygenase 1
HOMER2 homer scaffolding protein 2
HOOK1 hook microtubule-tethering protein 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ICAM1 intercellular adhesion molecule 1
IL11 interleukin 11
IL15RA interleukin 15 receptor, alpha
IQSEC2 IQ motif and Sec7 domain 2
ITFG2 integrin alpha FG-GAP repeat containing 2
KDM4D lysine (K)-specific demethylase 4D
LAMP1 lysosomal-associated membrane protein 1
LPP LIM domain containing preferred translocation partner in lipoma
LYN LYN proto-oncogene, Src family tyrosine kinase
MAPT microtubule-associated protein tau
MX1 MX dynamin-like GTPase 1
NINL ninein-like
NOTCH1 notch 1
NPEPL1 aminopeptidase-like 1
NPR3 natriuretic peptide receptor 3
NT5M 5',3'-nucleotidase, mitochondrial
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OSGIN1 oxidative stress induced growth inhibitor 1
PER1 period circadian clock 1
PHLDA3 pleckstrin homology-like domain, family A, member 3
PIDD1 p53-induced death domain protein 1
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLIN2 perilipin 2
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRMT2 protein arginine methyltransferase 2
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
PTPRU protein tyrosine phosphatase, receptor type, U
RANBP1 RAN binding protein 1
SBNO2 strawberry notch homolog 2 (Drosophila)
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC35G2 solute carrier family 35, member G2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMG5 SMG5 nonsense mediated mRNA decay factor
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SQSTM1 sequestosome 1
SUGP1 SURP and G patch domain containing 1
TBC1D19 TBC1 domain family, member 19
TBX2 T-box 2
TMEM132A transmembrane protein 132A
TRIM16 tripartite motif containing 16
TRIM66 tripartite motif containing 66
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSC22D4 TSC22 domain family, member 4
TUBA3C tubulin, alpha 3c
URI1 URI1, prefoldin-like chaperone
USB1 U6 snRNA biogenesis 1
ZFHX3 zinc finger homeobox 3
ZNF473 zinc finger protein 473
ZNF76 zinc finger protein 76
ZNF778 zinc finger protein 778

decreased expression

Symbol Name
AARSD1 alanyl-tRNA synthetase domain containing 1
ACADSB acyl-CoA dehydrogenase, short/branched chain
AMT aminomethyltransferase
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BATF3 basic leucine zipper transcription factor, ATF-like 3
BAX BCL2-associated X protein
BEX1 brain expressed, X-linked 1
BOLA1 bolA family member 1
CAMKMT calmodulin-lysine N-methyltransferase
CCL22 chemokine (C-C motif) ligand 22
CCP110 centriolar coiled coil protein 110kDa
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNGB3 cyclic nucleotide gated channel beta 3
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CUZD1 CUB and zona pellucida-like domains 1
CXCL3 chemokine (C-X-C motif) ligand 3
CYTH3 cytohesin 3
DPY19L2P2 DPY19L2 pseudogene 2
EDIL3 EGF-like repeats and discoidin I-like domains 3
EHF ets homologous factor
ELP6 elongator acetyltransferase complex subunit 6
ERCC5 excision repair cross-complementation group 5
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM120C family with sequence similarity 120C
FANCF Fanconi anemia, complementation group F
FER fer (fps/fes related) tyrosine kinase
FPGT fucose-1-phosphate guanylyltransferase
GMPR guanosine monophosphate reductase
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GTF2I general transcription factor IIi
H1F0 H1 histone family, member 0
HIRA histone cell cycle regulator
HIST1H3C histone cluster 1, H3c
HLX H2.0-like homeobox
HOXA1 homeobox A1
IFNB1 interferon, beta 1, fibroblast
INCENP inner centromere protein antigens 135/155kDa
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGA10 integrin, alpha 10
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KIRREL kin of IRRE like (Drosophila)
KLF7 Kruppel-like factor 7 (ubiquitous)
KLHL12 kelch-like family member 12
KLHL25 kelch-like family member 25
KRT86 keratin 86, type II
LNPEP leucyl/cystinyl aminopeptidase
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAPK12 mitogen-activated protein kinase 12
MB myoglobin
MBTPS2 membrane-bound transcription factor peptidase, site 2
MKS1 Meckel syndrome, type 1
MMP13 matrix metallopeptidase 13
MOXD1 monooxygenase, DBH-like 1
NARFL nuclear prelamin A recognition factor-like
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
NYNRIN NYN domain and retroviral integrase containing
PACS1 phosphofurin acidic cluster sorting protein 1
PADI1 peptidyl arginine deiminase, type I
PARD6A par-6 family cell polarity regulator alpha
PCDHGB5 protocadherin gamma subfamily B, 5
PECR peroxisomal trans-2-enoyl-CoA reductase
PLAG1 pleiomorphic adenoma gene 1
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
POMT2 protein-O-mannosyltransferase 2
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RGS2 regulator of G-protein signaling 2
RNF122 ring finger protein 122
RNF2 ring finger protein 2
RPL13P5 ribosomal protein L13 pseudogene 5
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
RPS17P5 ribosomal protein S17 pseudogene 5
SEPP1 selenoprotein P, plasma, 1
SERGEF secretion regulating guanine nucleotide exchange factor
SH2D2A SH2 domain containing 2A
SIPA1 signal-induced proliferation-associated 1
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SLN sarcolipin
SPAG16 sperm associated antigen 16
SYT17 synaptotagmin XVII
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TMEM177 transmembrane protein 177
TMEM38B transmembrane protein 38B
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TRDMT1 tRNA aspartic acid methyltransferase 1
TTF2 transcription termination factor, RNA polymerase II
UNC119 unc-119 homolog (C. elegans)
USP6 ubiquitin specific peptidase 6
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae)
ZNF226 zinc finger protein 226
ZNF276 zinc finger protein 276
ZNF415 zinc finger protein 415
ZNF573 zinc finger protein 573