5194442-6558 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the 5194442-6558 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
AMT aminomethyltransferase
ANKRD12 ankyrin repeat domain 12
ANXA1 annexin A1
ARHGAP4 Rho GTPase activating protein 4
ARTN artemin
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATXN2L ataxin 2-like
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BICD1 bicaudal D homolog 1 (Drosophila)
BIN1 bridging integrator 1
BMP7 bone morphogenetic protein 7
C21ORF2 chromosome 21 open reading frame 2
C3ORF52 chromosome 3 open reading frame 52
CA4 carbonic anhydrase IV
CCDC9 coiled-coil domain containing 9
CCPG1 cell cycle progression 1
CDK12 cyclin-dependent kinase 12
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CRTC1 CREB regulated transcription coactivator 1
DDIT3 DNA-damage-inducible transcript 3
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DST dystonin
ESR1 estrogen receptor 1
ETV5 ets variant 5
EXOC7 exocyst complex component 7
FAM155A family with sequence similarity 155, member A
FOSL1 FOS-like antigen 1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GCLM glutamate-cysteine ligase, modifier subunit
GLIPR1 GLI pathogenesis-related 1
GLRX glutaredoxin (thioltransferase)
GPR137 G protein-coupled receptor 137
GRB10 growth factor receptor-bound protein 10
HLA-C major histocompatibility complex, class I, C
HLA-DMA major histocompatibility complex, class II, DM alpha
HMOX1 heme oxygenase 1
HSPA1L heat shock 70kDa protein 1-like
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IL15RA interleukin 15 receptor, alpha
IL1R1 interleukin 1 receptor, type I
IRS2 insulin receptor substrate 2
JAG2 jagged 2
KAT8 K(lysine) acetyltransferase 8
KDM5A lysine (K)-specific demethylase 5A
LHX6 LIM homeobox 6
LINC00341 long intergenic non-protein coding RNA 341
LRP12 low density lipoprotein receptor-related protein 12
LYN LYN proto-oncogene, Src family tyrosine kinase
MAP1S microtubule-associated protein 1S
MAP2K7 mitogen-activated protein kinase kinase 7
MCM3AP minichromosome maintenance complex component 3 associated protein
MED16 mediator complex subunit 16
MEF2A myocyte enhancer factor 2A
MINK1 misshapen-like kinase 1
MIR22HG MIR22 host gene
MT1F metallothionein 1F
NCR1 natural cytotoxicity triggering receptor 1
NDRG1 N-myc downstream regulated 1
NFYA nuclear transcription factor Y, alpha
NMT2 N-myristoyltransferase 2
NOL12 nucleolar protein 12
NT5DC3 5'-nucleotidase domain containing 3
OSGIN1 oxidative stress induced growth inhibitor 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PADI1 peptidyl arginine deiminase, type I
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDHB3 protocadherin beta 3
PDE3B phosphodiesterase 3B, cGMP-inhibited
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RAB35 RAB35, member RAS oncogene family
RALGDS ral guanine nucleotide dissociation stimulator
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RARA retinoic acid receptor, alpha
RBM19 RNA binding motif protein 19
RGS12 regulator of G-protein signaling 12
ROM1 retinal outer segment membrane protein 1
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SETD1A SET domain containing 1A
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPTAN1 spectrin, alpha, non-erythrocytic 1
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TJAP1 tight junction associated protein 1 (peripheral)
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRABD TraB domain containing
TSC22D4 TSC22 domain family, member 4
TSPAN9 tetraspanin 9
TXNRD1 thioredoxin reductase 1
USP34 ubiquitin specific peptidase 34
ZNF141 zinc finger protein 141
ZNF189 zinc finger protein 189
ZNF43 zinc finger protein 43
ZSCAN12 zinc finger and SCAN domain containing 12

decreased expression

Symbol Name
AGBL5 ATP/GTP binding protein-like 5
AIDA axin interactor, dorsalization associated
ALDH18A1 aldehyde dehydrogenase 18 family, member A1
ARAF A-Raf proto-oncogene, serine/threonine kinase
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C14ORF93 chromosome 14 open reading frame 93
C1ORF56 chromosome 1 open reading frame 56
C4ORF19 chromosome 4 open reading frame 19
CCDC121 coiled-coil domain containing 121
CCP110 centriolar coiled coil protein 110kDa
CD34 CD34 molecule
CDK5 cyclin-dependent kinase 5
CFAP44 cilia and flagella associated protein 44
CHRM3 cholinergic receptor, muscarinic 3
CLMN calmin (calponin-like, transmembrane)
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DDA1 DET1 and DDB1 associated 1
DTX2 deltex 2, E3 ubiquitin ligase
ECHDC1 ethylmalonyl-CoA decarboxylase 1
EFNA1 ephrin-A1
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
FSTL3 follistatin-like 3 (secreted glycoprotein)
GAMT guanidinoacetate N-methyltransferase
GDE1 glycerophosphodiester phosphodiesterase 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLI3 GLI family zinc finger 3
GOLGA8B golgin A8 family, member B
HIST1H2AM histone cluster 1, H2am
HIST1H2BC histone cluster 1, H2bc
HLA-J major histocompatibility complex, class I, J (pseudogene)
HOXC4 homeobox C4
HPN hepsin
IGBP1 immunoglobulin (CD79A) binding protein 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCNK12 potassium channel, two pore domain subfamily K, member 12
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KCTD15 potassium channel tetramerization domain containing 15
KLHDC3 kelch domain containing 3
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LMBR1L limb development membrane protein 1-like
LMO2 LIM domain only 2 (rhombotin-like 1)
LOC100131532 uncharacterized LOC100131532
LOC642236 FSHD region gene 1 pseudogene
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAN2A1 mannosidase, alpha, class 2A, member 1
MB myoglobin
METTL16 methyltransferase like 16
MRPL2 mitochondrial ribosomal protein L2
MVD mevalonate (diphospho) decarboxylase
NAV2 neuron navigator 2
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
ODF2 outer dense fiber of sperm tails 2
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PARG poly (ADP-ribose) glycohydrolase
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLA2G10 phospholipase A2, group X
PLP2 proteolipid protein 2 (colonic epithelium-enriched)
PLTP phospholipid transfer protein
POGK pogo transposable element with KRAB domain
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PTDSS2 phosphatidylserine synthase 2
RNF43 ring finger protein 43
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SCML2 sex comb on midleg-like 2 (Drosophila)
SH3GLB2 SH3-domain GRB2-like endophilin B2
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC44A1 solute carrier family 44 (choline transporter), member 1
ST20 suppressor of tumorigenicity 20
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
ST5 suppression of tumorigenicity 5
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
THBS3 thrombospondin 3
TICAM1 toll-like receptor adaptor molecule 1
TMEM120B transmembrane protein 120B
TMEM230 transmembrane protein 230
TMEM53 transmembrane protein 53
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
TSPAN1 tetraspanin 1
TTPAL tocopherol (alpha) transfer protein-like
TUBA3C tubulin, alpha 3c
VIPR1 vasoactive intestinal peptide receptor 1
VPS9D1 VPS9 domain containing 1
WDR4 WD repeat domain 4
YIPF5 Yip1 domain family, member 5
ZBTB22 zinc finger and BTB domain containing 22
ZNF205 zinc finger protein 205
ZNF253 zinc finger protein 253
ZNF606 zinc finger protein 606
ZNF623 zinc finger protein 623
ZNF665 zinc finger protein 665