5194442-6594 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the 5194442-6594 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ADGRG2 adhesion G protein-coupled receptor G2
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ANGPTL4 angiopoietin-like 4
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AP3S2 adaptor-related protein complex 3, sigma 2 subunit
ARHGAP35 Rho GTPase activating protein 35
BTN3A2 butyrophilin, subfamily 3, member A2
BTN3A3 butyrophilin, subfamily 3, member A3
C16ORF58 chromosome 16 open reading frame 58
C16ORF59 chromosome 16 open reading frame 59
C4ORF29 chromosome 4 open reading frame 29
C7ORF43 chromosome 7 open reading frame 43
CACFD1 calcium channel flower domain containing 1
CD22 CD22 molecule
CD47 CD47 molecule
CD58 CD58 molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CFLAR CASP8 and FADD-like apoptosis regulator
CREBZF CREB/ATF bZIP transcription factor
CRY2 cryptochrome circadian clock 2
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
DAGLA diacylglycerol lipase, alpha
DBP D site of albumin promoter (albumin D-box) binding protein
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
DUSP10 dual specificity phosphatase 10
EFNB1 ephrin-B1
ELAVL2 ELAV like neuron-specific RNA binding protein 2
EPB41L1 erythrocyte membrane protein band 4.1-like 1
EPHB2 EPH receptor B2
EPS8L1 EPS8-like 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FABP4 fatty acid binding protein 4, adipocyte
FUZ fuzzy planar cell polarity protein
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GMEB1 glucocorticoid modulatory element binding protein 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GSTA1 glutathione S-transferase alpha 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HNF1B HNF1 homeobox B
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ICOSLG inducible T-cell co-stimulator ligand
ITFG2 integrin alpha FG-GAP repeat containing 2
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KIAA0930 KIAA0930
LIMK2 LIM domain kinase 2
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAP2K5 mitogen-activated protein kinase kinase 5
MAPK14 mitogen-activated protein kinase 14
METTL7A methyltransferase like 7A
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MTM1 myotubularin 1
NMT1 N-myristoyltransferase 1
OSGIN1 oxidative stress induced growth inhibitor 1
P3H2 prolyl 3-hydroxylase 2
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PDPN podoplanin
PITX1 paired-like homeodomain 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD)
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PROSER1 proline and serine rich 1
PRUNE prune exopolyphosphatase
PVT1 Pvt1 oncogene (non-protein coding)
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RNF126P1 ring finger protein 126 pseudogene 1
SCAMP5 secretory carrier membrane protein 5
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SYNGR3 synaptogyrin 3
TEX15 testis expressed 15
TM7SF2 transmembrane 7 superfamily member 2
TMCC1 transmembrane and coiled-coil domain family 1
TMCO3 transmembrane and coiled-coil domains 3
TMEM242 transmembrane protein 242
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TOR1AIP1 torsin A interacting protein 1
TPD52L1 tumor protein D52-like 1
TRIM16 tripartite motif containing 16
TTC17 tetratricopeptide repeat domain 17
TTLL7 tubulin tyrosine ligase-like family member 7
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
UNC5B unc-5 homolog B (C. elegans)
USB1 U6 snRNA biogenesis 1
VEGFA vascular endothelial growth factor A
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
ZNF324 zinc finger protein 324
ZNF671 zinc finger protein 671
ZNF821 zinc finger protein 821
ZNF93 zinc finger protein 93

decreased expression

Symbol Name
AFAP1 actin filament associated protein 1
AGRP agouti related neuropeptide
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
BAG4 BCL2-associated athanogene 4
BCAS3 breast carcinoma amplified sequence 3
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BEX4 brain expressed, X-linked 4
BMP4 bone morphogenetic protein 4
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BTC betacellulin
C22ORF29 chromosome 22 open reading frame 29
C8ORF44 chromosome 8 open reading frame 44
CASZ1 castor zinc finger 1
CEL carboxyl ester lipase
CENPQ centromere protein Q
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CINP cyclin-dependent kinase 2 interacting protein
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CPB2 carboxypeptidase B2 (plasma)
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DKFZP434L187 uncharacterized LOC26082
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
ELP3 elongator acetyltransferase complex subunit 3
ERC2-IT1 ERC2 intronic transcript 1
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERMP1 endoplasmic reticulum metallopeptidase 1
FAM131B family with sequence similarity 131, member B
FAM53B family with sequence similarity 53, member B
FAM86C1 family with sequence similarity 86, member C1
FBXL7 F-box and leucine-rich repeat protein 7
FKBP10 FK506 binding protein 10, 65 kDa
FLT4 fms-related tyrosine kinase 4
FZD8 frizzled class receptor 8
GAL3ST4 galactose-3-O-sulfotransferase 4
GIPR gastric inhibitory polypeptide receptor
GRAMD1C GRAM domain containing 1C
GREB1L growth regulation by estrogen in breast cancer-like
GSN-AS1 GSN antisense RNA 1
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene)
GTPBP2 GTP binding protein 2
HOXA4 homeobox A4
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
IFI6 interferon, alpha-inducible protein 6
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IGFLR1 IGF-like family receptor 1
KDM4D lysine (K)-specific demethylase 4D
KLF3 Kruppel-like factor 3 (basic)
LIMS2 LIM and senescent cell antigen-like domains 2
LRRC61 leucine rich repeat containing 61
MAGEF1 melanoma antigen family F1
MCOLN1 mucolipin 1
MEOX1 mesenchyme homeobox 1
MFGE8 milk fat globule-EGF factor 8 protein
MTERF1 mitochondrial transcription termination factor 1
MXD3 MAX dimerization protein 3
NDE1 nudE neurodevelopment protein 1
NEK11 NIMA-related kinase 11
NLK nemo-like kinase
NME5 NME/NM23 family member 5
NOL12 nucleolar protein 12
NPIPB15 nuclear pore complex interacting protein family, member B15
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PARP16 poly (ADP-ribose) polymerase family, member 16
PDGFRL platelet-derived growth factor receptor-like
PLD3 phospholipase D family, member 3
PLEKHA6 pleckstrin homology domain containing, family A member 6
PRR15L proline rich 15-like
PRSS16 protease, serine, 16 (thymus)
PTX3 pentraxin 3, long
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
RGS2 regulator of G-protein signaling 2
RNF123 ring finger protein 123
RNF2 ring finger protein 2
SCAMP3 secretory carrier membrane protein 3
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SERGEF secretion regulating guanine nucleotide exchange factor
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC25A40 solute carrier family 25, member 40
SLC41A3 solute carrier family 41, member 3
SLITRK5 SLIT and NTRK-like family, member 5
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBX19 T-box 19
TENM4 teneurin transmembrane protein 4
TGFBI transforming growth factor, beta-induced, 68kDa
TMEM209 transmembrane protein 209
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNRC6B trinucleotide repeat containing 6B
TRIM25 tripartite motif containing 25
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
WDR25 WD repeat domain 25
WNT10B wingless-type MMTV integration site family, member 10B
ZBTB38 zinc finger and BTB domain containing 38
ZNF205 zinc finger protein 205
ZNF215 zinc finger protein 215
ZNF273 zinc finger protein 273
ZNF446 zinc finger protein 446