5194442-6599 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the 5194442-6599 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ADAM22 ADAM metallopeptidase domain 22
ADARB1 adenosine deaminase, RNA-specific, B1
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
APLP1 amyloid beta (A4) precursor-like protein 1
ARTN artemin
AUTS2 autism susceptibility candidate 2
BAHCC1 BAH domain and coiled-coil containing 1
BIN1 bridging integrator 1
C14ORF93 chromosome 14 open reading frame 93
CASP3 caspase 3, apoptosis-related cysteine peptidase
CBR3 carbonyl reductase 3
CCDC22 coiled-coil domain containing 22
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CEP104 centrosomal protein 104kDa
CLCF1 cardiotrophin-like cytokine factor 1
CSF1 colony stimulating factor 1 (macrophage)
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DMC1 DNA meiotic recombinase 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DNM2 dynamin 2
DST dystonin
ESRRA estrogen-related receptor alpha
FDPS farnesyl diphosphate synthase
FSTL3 follistatin-like 3 (secreted glycoprotein)
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GCLM glutamate-cysteine ligase, modifier subunit
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GOSR2 golgi SNAP receptor complex member 2
GPR107 G protein-coupled receptor 107
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HIST1H4D histone cluster 1, H4d
HLA-F major histocompatibility complex, class I, F
HLA-G major histocompatibility complex, class I, G
HMGXB3 HMG box domain containing 3
HMHA1 histocompatibility (minor) HA-1
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ING1 inhibitor of growth family, member 1
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
JUN jun proto-oncogene
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KDM4B lysine (K)-specific demethylase 4B
LIG3 ligase III, DNA, ATP-dependent
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MED22 mediator complex subunit 22
MIR22HG MIR22 host gene
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
NCAPH2 non-SMC condensin II complex, subunit H2
OSGIN1 oxidative stress induced growth inhibitor 1
PAPOLA poly(A) polymerase alpha
PDE4DIP phosphodiesterase 4D interacting protein
PDGFB platelet-derived growth factor beta polypeptide
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PLCD1 phospholipase C, delta 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
POFUT1 protein O-fucosyltransferase 1
QKI QKI, KH domain containing, RNA binding
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RGS3 regulator of G-protein signaling 3
RNF2 ring finger protein 2
RPS4Y1 ribosomal protein S4, Y-linked 1
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
SCAMP1 secretory carrier membrane protein 1
SCAPER S-phase cyclin A-associated protein in the ER
SIRAL2 SIR2 antiphage like 2
SIRPA signal-regulatory protein alpha
SIRT3 sirtuin 3
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOWAHC sosondowah ankyrin repeat domain family member C
SPTBN1 spectrin, beta, non-erythrocytic 1
SQSTM1 sequestosome 1
STYK1 serine/threonine/tyrosine kinase 1
TCP10 t-complex 10
TCTN1 tectonic family member 1
TMEM161A transmembrane protein 161A
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRIM16 tripartite motif containing 16
TXNRD1 thioredoxin reductase 1
TYMS thymidylate synthetase
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
WDR48 WD repeat domain 48
YIPF2 Yip1 domain family, member 2
ZBTB17 zinc finger and BTB domain containing 17
ZMYM6 zinc finger, MYM-type 6
ZNF287 zinc finger protein 287
ZNF365 zinc finger protein 365
ZNF606 zinc finger protein 606
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ADGRG2 adhesion G protein-coupled receptor G2
AGMAT agmatine ureohydrolase (agmatinase)
ARC activity-regulated cytoskeleton-associated protein
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ATAD5 ATPase family, AAA domain containing 5
ATG2A autophagy related 2A
BAG4 BCL2-associated athanogene 4
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL9 B-cell CLL/lymphoma 9
BST2 bone marrow stromal cell antigen 2
C1ORF159 chromosome 1 open reading frame 159
C1ORF21 chromosome 1 open reading frame 21
C5AR1 complement component 5a receptor 1
CCP110 centriolar coiled coil protein 110kDa
CD53 CD53 molecule
CDK18 cyclin-dependent kinase 18
COMMD10 COMM domain containing 10
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CRISP2 cysteine-rich secretory protein 2
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYBA cytochrome b-245, alpha polypeptide
DGAT1 diacylglycerol O-acyltransferase 1
DGKG diacylglycerol kinase, gamma 90kDa
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EML4 echinoderm microtubule associated protein like 4
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERN2 endoplasmic reticulum to nucleus signaling 2
ETNK2 ethanolamine kinase 2
FAM120C family with sequence similarity 120C
FBRS fibrosin
FKBP10 FK506 binding protein 10, 65 kDa
GATA4 GATA binding protein 4
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GREB1L growth regulation by estrogen in breast cancer-like
GRTP1 growth hormone regulated TBC protein 1
HIRA histone cell cycle regulator
HIST1H2AJ histone cluster 1, H2aj
HIST2H2AA3 histone cluster 2, H2aa3
HOOK1 hook microtubule-tethering protein 1
IDI2-AS1 IDI2 antisense RNA 1
IFI6 interferon, alpha-inducible protein 6
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KIAA0125 KIAA0125
KLF3 Kruppel-like factor 3 (basic)
KLF7 Kruppel-like factor 7 (ubiquitous)
KLK5 kallikrein-related peptidase 5
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LOC257152 uncharacterized LOC257152
LY6G5C lymphocyte antigen 6 complex, locus G5C
LYPD1 LY6/PLAUR domain containing 1
MEFV Mediterranean fever
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MPDU1 mannose-P-dolichol utilization defect 1
MUC3B mucin 3B, cell surface associated
NDE1 nudE neurodevelopment protein 1
NKX3-2 NK3 homeobox 2
NR1D2 nuclear receptor subfamily 1, group D, member 2
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
ONECUT2 one cut homeobox 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDLIM2 PDZ and LIM domain 2 (mystique)
PLA2G3 phospholipase A2, group III
PMCH pro-melanin-concentrating hormone
POMT2 protein-O-mannosyltransferase 2
PRKCD protein kinase C, delta
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
SAYSD1 SAYSVFN motif domain containing 1
SIGLEC15 sialic acid binding Ig-like lectin 15
SKA1 spindle and kinetochore associated complex subunit 1
SLC25A40 solute carrier family 25, member 40
SMA4 glucuronidase, beta pseudogene
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
TARP TCR gamma alternate reading frame protein
TCTN2 tectonic family member 2
TDRD1 tudor domain containing 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMLHE trimethyllysine hydroxylase, epsilon
TRAIP TRAF interacting protein
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
UCN urocortin
VAX2 ventral anterior homeobox 2
VN1R1 vomeronasal 1 receptor 1
ZBTB44 zinc finger and BTB domain containing 44
ZNF639 zinc finger protein 639
ZNF76 zinc finger protein 76
ZNF85 zinc finger protein 85
ZSCAN31 zinc finger and SCAN domain containing 31